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Protein

Probable transaldolase

Gene

tal

Organism
Methanococcus maripaludis (strain S2 / LL)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei83Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

BioCyciMMAR267377:G1G3S-1350-MONOMER.
UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:MMP1308
OrganismiMethanococcus maripaludis (strain S2 / LL)
Taxonomic identifieri267377 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000590 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000604721 – 215Probable transaldolaseAdd BLAST215

Interactioni

Protein-protein interaction databases

STRINGi267377.MMP1308.

Structurei

3D structure databases

ProteinModelPortaliQ6LXP1.
SMRiQ6LXP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3B subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG05061. Archaea.
COG0176. LUCA.
HOGENOMiHOG000226073.
KOiK00616.
OMAiVRHPMHV.
OrthoDBiPOG093Z08KS.

Family and domain databases

CDDicd00956. Transaldolase_FSA. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00494. Transaldolase_3b. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR001585. TAL/FSA.
IPR022999. Transaldolase_3B.
IPR004731. Transaldolase_3B/F6P_aldolase.
IPR018225. Transaldolase_AS.
IPR033919. TSA/FSA_arc/bac.
PANTHERiPTHR10683. PTHR10683. 2 hits.
PfamiView protein in Pfam
PF00923. TAL_FSA. 1 hit.
TIGRFAMsiTIGR00875. fsa_talC_mipB. 1 hit.
PROSITEiView protein in PROSITE
PS01054. TRANSALDOLASE_1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6LXP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFFLDTANV EKIKEFNALG LVDGVTTNPS LIKKEGRDFY EVIKEICSIV
60 70 80 90 100
DGPVSAEVIA LDSEGMVKEA RELVKLAENV VVKIPMTKEG MKAVNILSKE
110 120 130 140 150
GIKTNVTLIF SANQALLAAK AGASYVSPFV GRLDDVGQDG MFLISEVMQV
160 170 180 190 200
FGAYGIETEV IVASVRHPIH VLESAKMGAD IATIPFDVLD KLFNHPLTDN
210
GIAKFLSDWE AHMNR
Length:215
Mass (Da):23,442
Last modified:July 5, 2004 - v1
Checksum:i5A40602AD6242F59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950229 Genomic DNA. Translation: CAF30864.1.
RefSeqiWP_011171252.1. NC_005791.1.

Genome annotation databases

EnsemblBacteriaiCAF30864; CAF30864; MMP1308.
GeneIDi2762583.
KEGGimmp:MMP1308.
PATRICifig|267377.15.peg.1343.

Similar proteinsi

Entry informationi

Entry nameiTAL_METMP
AccessioniPrimary (citable) accession number: Q6LXP1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome