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Protein

DNA-directed RNA polymerase subunit A''

Gene

rpoA2

Organism
Methanococcus maripaludis (strain S2 / LL)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit A''UniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:rpoA2UniRule annotation
Ordered Locus Names:MMP1364
OrganismiMethanococcus maripaludis (strain S2 / LL)
Taxonomic identifieri267377 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000590 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000499281 – 386DNA-directed RNA polymerase subunit A''Add BLAST386

Interactioni

Protein-protein interaction databases

STRINGi267377.MMP1364.

Structurei

3D structure databases

ProteinModelPortaliQ6LXI7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

CDDicd06528. RNAP_A''. 1 hit.
HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6LXI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQMADLEKKL ENSVLPPLLK RELSEKILRE EISEEYLVDE IISETTRAYE
60 70 80 90 100
RTLVEPGEAV GVVAAQSIGE PGTQMTMRTF HYAGVAELNV TLGLPRMIEI
110 120 130 140 150
VDARKEPSTP TMTIYLNDEF KGNREKAATV AKNIESTNVE SVSEDISVDL
160 170 180 190 200
VNECITIILN NQQLESRGLT VPDVIDAIKS KMKLKIEDHE NVLNLKIKTP
210 220 230 240 250
SLKALRKRLP KVRAIHLKGV QNIKRVIIRK EVDEYILYSE GSNIKEVFDI
260 270 280 290 300
EGVDTTKTTT NNIVEIQDVL GIEAARNAII YEMDATLGNQ GLTVDKRHLM
310 320 330 340 350
MVADLMCTDG VVKPIGRHGI GGEKASVLAR AAFEETVKHL YSASMRGYVD
360 370 380
ELGGVVENII VGKPISMGTG CIDICIDKSY EEGKEL
Length:386
Mass (Da):42,795
Last modified:July 5, 2004 - v1
Checksum:i5C77DAEDB6FAA0E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950229 Genomic DNA. Translation: CAF30920.1.
RefSeqiWP_011171308.1. NC_005791.1.

Genome annotation databases

EnsemblBacteriaiCAF30920; CAF30920; MMP1364.
GeneIDi2762458.
KEGGimmp:MMP1364.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950229 Genomic DNA. Translation: CAF30920.1.
RefSeqiWP_011171308.1. NC_005791.1.

3D structure databases

ProteinModelPortaliQ6LXI7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267377.MMP1364.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAF30920; CAF30920; MMP1364.
GeneIDi2762458.
KEGGimmp:MMP1364.

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

CDDicd06528. RNAP_A''. 1 hit.
HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRPOA2_METMP
AccessioniPrimary (citable) accession number: Q6LXI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.