Q6LXC6 (DCD_METMP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	MMP1426

Organism

Methanococcus maripaludis (strain S2 / LL) [Complete proteome] [HAMAP]

Taxonomic identifier

267377 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	206 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 206	206	Probable deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000156031

Sequences

	Sequence		Length	Mass (Da)
	Q6LXC6 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 31B12943F0942043	FASTA	206	23,388
	10 20 30 40 50 60 MILSDKDIFN YVTSKRVLIE PFNSKFVGPC SYDVTLGSEF IKYNEDVYDV KKTLNHSKFK 70 80 90 100 110 120 IENSVMVCPL NHHLDETIIK NYKEKYNVDC VVSGGLLGTT NEYVELPNDV CAQYQGRSSF 130 140 150 160 170 180 GRVFLQTHQT AGWIDSGFKG KITLEIVAYD KPVILYKNQR VGQLIFSKTL SPADIGYSDR 190 200 KCSKYAGQTS VMASLIKKDF ETNEEE

References

[1]

"Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis." Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J., Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M., Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A., Moore B.C. , Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D., Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W., Olson M.V., Leigh J.A. J. Bacteriol. 186:6956-6969(2004) [PubMed: 15466049] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S2 / LL.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950229 Genomic DNA. Translation: CAF30982.1.
RefSeq	NP_988546.1. NC_005791.1.
3D structure databases
ProteinModelPortal	Q6LXC6.
SMR	Q6LXC6. Positions 1-199.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2761835.
GenomeReviews	Gene locus MMP1426 in contig BX950229_GR.
KEGG	mmp:MMP1426.
NMPDR	fig|267377.1.peg.1426.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553199.
OMA	HQTAGWI.
ProtClustDB	CLSK876187.
Enzyme and pathway databases
BioCyc	MMAR267377:MMP1426-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METMP

Accession

Primary (citable) accession number: Q6LXC6

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	July 5, 2004
Last modified:	November 16, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program