Q6LXB3 (APGM_METMP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	MMP1439

Organism

Methanococcus maripaludis (strain S2 / LL) [Complete proteome] [HAMAP]

Taxonomic identifier

267377 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 406	406	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_0000138138

Sequences

	Sequence		Length	Mass (Da)
	Q6LXB3 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4251A8FEA058080C	FASTA	406	44,464
	10 20 30 40 50 60 MKAVIFVVDG LGDRPDKNGN TPLKEAKTPV MDRMAKEGIC GLMNSVDIGV RPGSDTAHLA 70 80 90 100 110 120 LLGYDPYTTY TGRGPFEACG VGVTVKPGDI AFRCNFSSVD ENFIVTDRRA GRIENTSELE 130 140 150 160 170 180 KELDGLKIDD VEIIFKESGG YRAALVLRGP GLSDKITDAD PKKEGKKVKE IHPLDDSKEA 190 200 210 220 230 240 KKTAEIVNKL LKIAYEKLDK HPVNEERRKQ NLPVANMIVP RGVGQVPEIM QFTEKTGLKG 250 260 270 280 290 300 ACIAGTGLIK GIAKMVGLDV IDVEGCDGTP DSDFMAKACA IVETLENYDF ILVNVKGADE 310 320 330 340 350 360 AGHDGNYELK KQVIEKVDEM LDYITKNISK DEVYFVLSGD HSTPIEEMDH SADPLPVVLW 370 380 390 400 GKSVRVDDVE KFDEFSTYKG GLNWIKGVHI MPILLDLMGL AKKYGA

References

[1]

"Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis." Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J., Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M., Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A., Moore B.C. , Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D., Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W., Olson M.V., Leigh J.A. J. Bacteriol. 186:6956-6969(2004) [PubMed: 15466049] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S2 / LL.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950229 Genomic DNA. Translation: CAF30995.1.
RefSeq	NP_988559.1. NC_005791.1.
3D structure databases
ProteinModelPortal	Q6LXB3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2761971.
GenomeReviews	Gene locus MMP1439 in contig BX950229_GR.
KEGG	mmp:MMP1439.
NMPDR	fig|267377.1.peg.1439.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG463247.
OMA	DIAFRCN.
ProtClustDB	PRK04024.
Enzyme and pathway databases
BioCyc	MMAR267377:MMP1439-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METMP

Accession

Primary (citable) accession number: Q6LXB3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program