Reviewed,
UniProtKB/Swiss-Prot Q6LWL8 (FWDB_METMP)
Last modified
November 3, 2009.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Tungsten-containing formylmethanofuran dehydrogenase 2 subunit B EC=1.2.99.5 Alternative name(s): Tungsten-containing formylmethanofuran dehydrogenase II subunit B | ||||
| Gene names |
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| Organism | Methanococcus maripaludis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 39152 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus |
Protein attributes
| Sequence length | 434 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes the reversible oxidation of CO2 and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile By similarity. |
| Catalytic activity | Formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor. |
| Cofactor | Tungsten By similarity. |
| Pathway | |
| Subunit structure | This enzyme is composed of six subunits fwdA, fwdC, fwdD, fwdE, fwdF and fwdG By similarity. |
| Sequence similarities | Belongs to the fwdB family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Methanogenesis |
| Coding sequence diversity | Selenocysteine |
| Ligand | Selenium Tungsten |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | methanogenesis Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | formylmethanofuran dehydrogenase activity Inferred from electronic annotation. Source: EC selenium bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis." Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J., Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M., Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A., Moore B.C. Leigh J.A.J. Bacteriol. 186:6956-6969(2004) [PubMed: 15466049] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S2 / LL. |
Cross-references
Sequence databases | |
|---|---|
| BX950229 Genomic DNA. Translation: CAF31247.1. | |
| RefSeq | NP_988811.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2762359. |
| GenomeReviews | Gene locus MMP1691 in contig BX950229_GR. |
| KEGG | mmp:MMP1691. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q6LWL8. |
| OMA | NVVCPFC. |
Enzyme and pathway databases | |
| BRENDA | 1.2.99.5. 20956. |
Family and domain databases | |
| InterPro | IPR016457. Formylmethanofuran_DH_bsu. [Graphical view] |
| PIRSF | PIRSF005646. FwdB. 1 hit. |
| TIGRFAMs | TIGR03129. one_C_dehyd_B. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | FWDB_METMP | ||||||||
| Accession | Primary (citable) accession number: Q6LWL8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


