Reviewed, UniProtKB/Swiss-Prot Q6LVS4 (UBIC_PHOPR)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	PBPRA0162

Organism

Photobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]

Taxonomic identifier

74109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity HAMAP MF_01632.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000240552
Sites
	Binding site	82	1	Substrate By similarity
	Binding site	120	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6LVS4-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: ADB8B8573D2FEF16	FASTA	180	20,515
	10 20 30 40 50 60 MSKFKQLYKP LLDNAQWETP LSLAIEGTAF GHWLLEPNSL SRRLQRHCDE FTVSLIEQKK 70 80 90 100 110 120 IDSTMLSADE RELIGDVDCL LRKVVLMGDG QPWVFARTLI PLSTLTGQES DLEQLGEMPL 130 140 150 160 170 180 GFRVFTDRSA RRDALEVANT GTQAQPLWAR RSRLWINNKP LLVAELFLAQ APVYSKEKQC

References

[1]

"Life at depth: Photobacterium profundum genome sequence and expression analysis." Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G. Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR378663 Genomic DNA. Translation: CAG18601.1.
RefSeq	YP_128403.1.
3D structure databases
SMR	Q6LVS4. Positions 28-174.
ModBase	Search...
Genome annotation databases
GeneID	3124988.
KEGG	ppr:PBPRA0162.
NMPDR	fig|298386.1.peg.2384.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644467.
OMA	QPWVFAR.
PhylomeDB	Q6LVS4.
Enzyme and pathway databases
BioCyc	PPRO298386:PBPRA0162-MONOMER.
BRENDA	4.1.3.40. 263915.
Family and domain databases
HAMAP	MF_01632. UbiC. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_PHOPR

Accession

Primary (citable) accession number: Q6LVS4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	July 5, 2004
Last modified:	February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)