Reviewed,
UniProtKB/Swiss-Prot Q6LUW9 (OTCC_PHOPR)
Last modified
November 3, 2009.
Version 41.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Ornithine carbamoyltransferase, catabolic Short name=OTCase EC=2.1.3.3 | ||||
| Gene names |
| ||||
| Organism | Photobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 74109 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium |
Protein attributes
| Sequence length | 336 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. HAMAP MF_01109 |
| Pathway | Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 2/2. HAMAP MF_01109 |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the ATCase/OTCase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Arginine metabolism |
| Cellular component | Cytoplasm |
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | arginine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | ornithine carbamoyltransferase complex Inferred from electronic annotation. Source: InterPro |
| Molecular function | amino acid binding Inferred from electronic annotation. Source: InterPro ornithine carbamoyltransferase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 336 | 336 | Ornithine carbamoyltransferase, catabolic HAMAP MF_01109 | PRO_0000112980 | |||||
Regions | |||||||||
| Region | 57 – 61 | 5 | Carbamoyl phosphate binding By similarity | ||||||
| Region | 274 – 277 | 4 | Ornithine binding By similarity | ||||||
Sites | |||||||||
| Binding site | 108 | 1 | Carbamoyl phosphate By similarity | ||||||
| Binding site | 135 | 1 | Carbamoyl phosphate By similarity | ||||||
| Site | 32 | 1 | Important for structural integrity By similarity | ||||||
| Site | 148 | 1 | Important for structural integrity By similarity | ||||||
Sequences
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References
| [1] | "Life at depth: Photobacterium profundum genome sequence and expression analysis." Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G. Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CR378664 Genomic DNA. Translation: CAG18906.1. | |
| RefSeq | YP_128708.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1AKM based on UniProtKB P04391. |
| SMR | Q6LUW9. Positions 7-336. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 3122547. |
| GenomeReviews | Gene locus PBPRA0475 in contig CR354531_GR. |
| KEGG | ppr:PBPRA0475. |
| NMPDR | fig|298386.1.peg.2704. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q6LUW9. |
| OMA | NPNVKFM. |
Enzyme and pathway databases | |
| BioCyc | PPRO298386:PBPRA0475-MON. |
| BRENDA | 2.1.3.3. 263915. |
Family and domain databases | |
| HAMAP | MF_01109. [Tree] |
| InterPro | IPR006132. Asp/Orn_carbamoyltranf_P_bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn_bd. IPR002292. Orn_carbamltrans. [Graphical view] |
| Pfam | PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view] |
| PRINTS | PR00100. AOTCASE. PR00102. OTCASE. |
| TIGRFAMs | TIGR00658. orni_carb_tr. 1 hit. |
| PROSITE | PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | OTCC_PHOPR | ||||||||
| Accession | Primary (citable) accession number: Q6LUW9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


