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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Photobacterium profundum (strain SS9)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:PBPRA0819
OrganismiPhotobacterium profundum (strain SS9)
Taxonomic identifieri298386 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
Proteomesi
  • UP000000593 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 374374Ribosomal RNA large subunit methyltransferase GPRO_0000366469Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi298386.PBPRA0819.

Structurei

3D structure databases

ProteinModelPortaliQ6LTZ3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiEOG67X1ZC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6LTZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPALTLHDR TLKLNRFPIR KIETLQAWDA ADEYLINHTH DMELDPQRPI
60 70 80 90 100
LILNDSFGAL SCWFAERANV TTVTDSFVAK QGCIANLTAN QLPSVNIIDC
110 120 130 140 150
LAELPKNPQL VLIKLPKNNR LLTWQLQQLC HLLPEDCRVI GAAKVKDIHT
160 170 180 190 200
STLKLCDKYL GETKTSLAVK KARLVFIKPN ASLAKPMPEA KAWDVPEHGI
210 220 230 240 250
RLSNHANVFS GESLDIGARL LLNHIPQDFK YKDIIDLGCG NGVIGIKAAR
260 270 280 290 300
RNPQAKITCV DESFMAAASC TENAKQNLEA PEQLTAIVTD CLADIEHSSA
310 320 330 340 350
DLVLCNPPFH QQTTITDHIA WQMFCDAKQV LRPKGELIVI GNRQLGYDDK
360 370
LKRLFGNVEI IAQNDKFIVY QSVK
Length:374
Mass (Da):41,755
Last modified:July 5, 2004 - v1
Checksum:iBF8E711F7888A1D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378665 Genomic DNA. Translation: CAG19232.1.
RefSeqiWP_011217570.1. NC_006370.1.

Genome annotation databases

EnsemblBacteriaiCAG19232; CAG19232; PBPRA0819.
KEGGippr:PBPRA0819.
PATRICi22932357. VBIPhoPro109272_0900.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378665 Genomic DNA. Translation: CAG19232.1.
RefSeqiWP_011217570.1. NC_006370.1.

3D structure databases

ProteinModelPortaliQ6LTZ3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi298386.PBPRA0819.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAG19232; CAG19232; PBPRA0819.
KEGGippr:PBPRA0819.
PATRICi22932357. VBIPhoPro109272_0900.

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiEOG67X1ZC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1253 / SS9.

Entry informationi

Entry nameiRLMG_PHOPR
AccessioniPrimary (citable) accession number: Q6LTZ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 5, 2004
Last modified: May 11, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.