Reviewed, UniProtKB/Swiss-Prot Q6LTZ3 (RLMG_PHOPR)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA large subunit methyltransferase G
    EC=2.1.1.52
Alternative name(s):
    rRNA (guanine-N(2)-)-methyltransferase rlmG
    23S rRNA m2G1835 methyltransferase

Gene names

Name:	rlmG
Ordered Locus Names:	PBPRA0819

Organism

Photobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]

Taxonomic identifier

74109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium

Protein attributes

Sequence length	374 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(2)-methylguanine. HAMAP MF_01859
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 374	374	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366469

Sequences

	Sequence		Length	Mass (Da)
	Q6LTZ3-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: BF8E711F7888A1D5	FASTA	374	41,755
	10 20 30 40 50 60 MKPALTLHDR TLKLNRFPIR KIETLQAWDA ADEYLINHTH DMELDPQRPI LILNDSFGAL 70 80 90 100 110 120 SCWFAERANV TTVTDSFVAK QGCIANLTAN QLPSVNIIDC LAELPKNPQL VLIKLPKNNR 130 140 150 160 170 180 LLTWQLQQLC HLLPEDCRVI GAAKVKDIHT STLKLCDKYL GETKTSLAVK KARLVFIKPN 190 200 210 220 230 240 ASLAKPMPEA KAWDVPEHGI RLSNHANVFS GESLDIGARL LLNHIPQDFK YKDIIDLGCG 250 260 270 280 290 300 NGVIGIKAAR RNPQAKITCV DESFMAAASC TENAKQNLEA PEQLTAIVTD CLADIEHSSA 310 320 330 340 350 360 DLVLCNPPFH QQTTITDHIA WQMFCDAKQV LRPKGELIVI GNRQLGYDDK LKRLFGNVEI 370 IAQNDKFIVY QSVK

References

[1]

"Life at depth: Photobacterium profundum genome sequence and expression analysis." Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G. Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR378665 Genomic DNA. Translation: CAG19232.1.
RefSeq	YP_129034.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3122084.
GenomeReviews	Gene locus PBPRA0819 in contig CR354531_GR.
KEGG	ppr:PBPRA0819.
NMPDR	fig|298386.1.peg.3047.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6LTZ3.
OMA	NRHLGYH.
Enzyme and pathway databases
BioCyc	PPRO298386:PBPRA0819-MON.
Family and domain databases
HAMAP	MF_01859. [Tree]
InterPro	IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_PHOPR

Accession

Primary (citable) accession number: Q6LTZ3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 5, 2004
Last modified:	November 3, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)