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Reviewed, UniProtKB/Swiss-Prot Q6LTD1 (SYQ_PHOPR)

Last modified February 9, 2010. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Glutaminyl-tRNA synthetase
    EC=6.1.1.18
Alternative name(s):
    Glutamine--tRNA ligase
      Short name=GlnRS
Gene names
Name: glnS
Ordered Locus Names: PBPRA1034
OrganismPhotobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]
Taxonomic identifier74109 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium

Protein attributes

Sequence length555 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP MF_00126

Subunit structure

Monomer By similarity. HAMAP MF_00126

Subcellular location

Cytoplasm HAMAP MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 555555Glutaminyl-tRNA synthetase HAMAP MF_00126
PRO_0000242872

Regions

Motif35 – 4511"HIGH" region HAMAP MF_00126
Motif269 – 2735"KMSKS" region HAMAP MF_00126

Sites

Binding site2721ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6LTD1-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: A589F55D8C022BA5

FASTA55563,594
        10         20         30         40         50         60 
MMSESEARPT NFIRQIIDAD LDSGKHKSVH TRFPPEPNGY LHIGHAKSIC LNFGIAQDYQ 

        70         80         90        100        110        120 
GQCNLRFDDT NPEKEDIEYV ESIKNDVNWL GFDWSGEICY SSNYFDKLYG FAVELINKGL 

       130        140        150        160        170        180 
AYVDELSPEQ MREYRGNLTE PGKPSPYRDR SVAENLELFE KMKNGEVEEG IMSLRAKIDM 

       190        200        210        220        230        240 
ASSFMVLRDP VIYRVRFATH HQTGDKWCIY PMYDFTHCIS DALEGITHSI CTLEFQDNRR 

       250        260        270        280        290        300 
LYDWVLDNIT IDCQPRQYEF SRLNLEYTVM SKRKLNQLVT DNLVSGWDDP RMPTVSGLRR 

       310        320        330        340        350        360 
RGFTSASIRE FCKRIGVTKQ ENTIEMSSLE SCIRDDLNEN APRAMAVLDP VKIVIENFTG 

       370        380        390        400        410        420 
DTEVLTVSNH PNNSEMGTRE VPFTREIWIE REDFREEANK KYKRLVLGKE VRLRGAYVIK 

       430        440        450        460        470        480 
AERIEKDAEG NITTIFCSYD NETLGVNPSD GRKVKGVIHW VSADAGLPAE IRLYDRLFTV 

       490        500        510        520        530        540 
ANPAAADDFV TVINPESLTV LNGFVEPSLK VAEAEKAFQF ERIGYFCVDS KDSSAEKLVF 

       550 
NRTVGLRDTW AKMGE 

« Hide

References

[1]"Life at depth: Photobacterium profundum genome sequence and expression analysis."
Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G.
Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR378666 Genomic DNA. Translation: CAG19445.1.
RefSeqYP_129247.1.

3D structure databases

SMRQ6LTD1. Positions 10-549.
ModBaseSearch...

Genome annotation databases

GeneID3122893.
KEGGppr:PBPRA1034.
NMPDRfig|298386.1.peg.3269.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG334108.
OMARMPTIAG.
PhylomeDBQ6LTD1.

Enzyme and pathway databases

BioCycPPRO298386:PBPRA1034-MONOMER.
BRENDA6.1.1.18. 263915.

Family and domain databases

HAMAPMF_00126. Gln_tRNA_synth.
[Tree]
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth_Ic.
IPR000924. Glu/Gln-tRNA-synth_Ic.
IPR020061. Glu/Gln-tRNA-synth_Ic_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ic_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ic_codon-bd.
IPR020060. Glu/Gln-tRNA-synth_Ic_N.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
[Graphical view]
Gene3DG3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit.
G3DSA:2.40.240.10. Rbsml_L25/Gln-tRNA_synth_b-brl. 1 hit.
PANTHERPTHR10119:SF3. GlnS. 1 hit.
PTHR10119. Glu_tRNA-synt_1c. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_PHOPR
AccessionPrimary (citable) accession number: Q6LTD1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents