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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Photobacterium profundum (strain SS9)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei68L-glutamineUniRule annotation1
Binding sitei213L-glutamineUniRule annotation1
Binding sitei232ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi36 – 38ATPUniRule annotation3
Nucleotide bindingi42 – 48ATPUniRule annotation7
Nucleotide bindingi262 – 263ATPUniRule annotation2
Nucleotide bindingi270 – 272ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:PBPRA1034
OrganismiPhotobacterium profundum (strain SS9)
Taxonomic identifieri298386 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
Proteomesi
  • UP000000593 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002428721 – 555Glutamine--tRNA ligaseAdd BLAST555

Proteomic databases

PRIDEiQ6LTD1.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi298386.PBPRA1034.

Structurei

3D structure databases

ProteinModelPortaliQ6LTD1.
SMRiQ6LTD1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi35 – 45"HIGH" regionUniRule annotationAdd BLAST11
Motifi269 – 273"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6LTD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSESEARPT NFIRQIIDAD LDSGKHKSVH TRFPPEPNGY LHIGHAKSIC
60 70 80 90 100
LNFGIAQDYQ GQCNLRFDDT NPEKEDIEYV ESIKNDVNWL GFDWSGEICY
110 120 130 140 150
SSNYFDKLYG FAVELINKGL AYVDELSPEQ MREYRGNLTE PGKPSPYRDR
160 170 180 190 200
SVAENLELFE KMKNGEVEEG IMSLRAKIDM ASSFMVLRDP VIYRVRFATH
210 220 230 240 250
HQTGDKWCIY PMYDFTHCIS DALEGITHSI CTLEFQDNRR LYDWVLDNIT
260 270 280 290 300
IDCQPRQYEF SRLNLEYTVM SKRKLNQLVT DNLVSGWDDP RMPTVSGLRR
310 320 330 340 350
RGFTSASIRE FCKRIGVTKQ ENTIEMSSLE SCIRDDLNEN APRAMAVLDP
360 370 380 390 400
VKIVIENFTG DTEVLTVSNH PNNSEMGTRE VPFTREIWIE REDFREEANK
410 420 430 440 450
KYKRLVLGKE VRLRGAYVIK AERIEKDAEG NITTIFCSYD NETLGVNPSD
460 470 480 490 500
GRKVKGVIHW VSADAGLPAE IRLYDRLFTV ANPAAADDFV TVINPESLTV
510 520 530 540 550
LNGFVEPSLK VAEAEKAFQF ERIGYFCVDS KDSSAEKLVF NRTVGLRDTW

AKMGE
Length:555
Mass (Da):63,594
Last modified:July 5, 2004 - v1
Checksum:iA589F55D8C022BA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378666 Genomic DNA. Translation: CAG19445.1.

Genome annotation databases

EnsemblBacteriaiCAG19445; CAG19445; PBPRA1034.
KEGGippr:PBPRA1034.

Similar proteinsi

Entry informationi

Entry nameiSYQ_PHOPR
AccessioniPrimary (citable) accession number: Q6LTD1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families