Reviewed, UniProtKB/Swiss-Prot Q6LTD1 (SYQ_PHOPR)

Names and origin

Protein names

Recommended name:
    Glutaminyl-tRNA synthetase
    EC=6.1.1.18
Alternative name(s):
    Glutamine--tRNA ligase
      Short name=GlnRS

Gene names

Name:	glnS
Ordered Locus Names:	PBPRA1034

Organism

Photobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]

Taxonomic identifier

74109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium

Protein attributes

Sequence length	555 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP MF_00126
Subunit structure	Monomer By similarity. HAMAP MF_00126
Subcellular location	Cytoplasm HAMAP MF_00126.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glutaminyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro glutamyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glutamine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 555	555	Glutaminyl-tRNA synthetase HAMAP MF_00126		PRO_0000242872
Regions
	Motif	35 – 45	11	"HIGH" region HAMAP MF_00126
	Motif	269 – 273	5	"KMSKS" region HAMAP MF_00126
Sites
	Binding site	272	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6LTD1-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: A589F55D8C022BA5	FASTA	555	63,594
	10 20 30 40 50 60 MMSESEARPT NFIRQIIDAD LDSGKHKSVH TRFPPEPNGY LHIGHAKSIC LNFGIAQDYQ 70 80 90 100 110 120 GQCNLRFDDT NPEKEDIEYV ESIKNDVNWL GFDWSGEICY SSNYFDKLYG FAVELINKGL 130 140 150 160 170 180 AYVDELSPEQ MREYRGNLTE PGKPSPYRDR SVAENLELFE KMKNGEVEEG IMSLRAKIDM 190 200 210 220 230 240 ASSFMVLRDP VIYRVRFATH HQTGDKWCIY PMYDFTHCIS DALEGITHSI CTLEFQDNRR 250 260 270 280 290 300 LYDWVLDNIT IDCQPRQYEF SRLNLEYTVM SKRKLNQLVT DNLVSGWDDP RMPTVSGLRR 310 320 330 340 350 360 RGFTSASIRE FCKRIGVTKQ ENTIEMSSLE SCIRDDLNEN APRAMAVLDP VKIVIENFTG 370 380 390 400 410 420 DTEVLTVSNH PNNSEMGTRE VPFTREIWIE REDFREEANK KYKRLVLGKE VRLRGAYVIK 430 440 450 460 470 480 AERIEKDAEG NITTIFCSYD NETLGVNPSD GRKVKGVIHW VSADAGLPAE IRLYDRLFTV 490 500 510 520 530 540 ANPAAADDFV TVINPESLTV LNGFVEPSLK VAEAEKAFQF ERIGYFCVDS KDSSAEKLVF 550 NRTVGLRDTW AKMGE

References

[1]

"Life at depth: Photobacterium profundum genome sequence and expression analysis." Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G. Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR378666 Genomic DNA. Translation: CAG19445.1.
RefSeq	YP_129247.1.
3D structure databases
SMR	Q6LTD1. Positions 10-549.
ModBase	Search...
Genome annotation databases
GeneID	3122893.
KEGG	ppr:PBPRA1034.
NMPDR	fig|298386.1.peg.3269.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG334108.
OMA	RMPTIAG.
PhylomeDB	Q6LTD1.
Enzyme and pathway databases
BioCyc	PPRO298386:PBPRA1034-MONOMER.
BRENDA	6.1.1.18. 263915.
Family and domain databases
HAMAP	MF_00126. Gln_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR004514. Gln-tRNA-synth_Ic. IPR000924. Glu/Gln-tRNA-synth_Ic. IPR020061. Glu/Gln-tRNA-synth_Ic_a-bdl. IPR020058. Glu/Gln-tRNA-synth_Ic_cat-dom. IPR020059. Glu/Gln-tRNA-synth_Ic_codon-bd. IPR020060. Glu/Gln-tRNA-synth_Ic_N. IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl. IPR011035. Ribosomal_L25/Gln-tRNA_synth. [Graphical view]
Gene3D	G3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit. G3DSA:2.40.240.10. Rbsml_L25/Gln-tRNA_synth_b-brl. 1 hit.
PANTHER	PTHR10119:SF3. GlnS. 1 hit. PTHR10119. Glu_tRNA-synt_1c. 1 hit.
Pfam	PF00749. tRNA-synt_1c. 1 hit. PF03950. tRNA-synt_1c_C. 1 hit. [Graphical view]
PRINTS	PR00987. TRNASYNTHGLU.
TIGRFAMs	TIGR00440. glnS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYQ_PHOPR

Accession

Primary (citable) accession number: Q6LTD1

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	July 5, 2004
Last modified:	February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)