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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Photobacterium profundum (strain SS9)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:PBPRA1064
OrganismiPhotobacterium profundum (strain SS9)
Taxonomic identifieri298386 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
Proteomesi
  • UP000000593 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420641 – 576Arginine--tRNA ligaseAdd BLAST576

Proteomic databases

PRIDEiQ6LTA1.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi298386.PBPRA1064.

Structurei

3D structure databases

ProteinModelPortaliQ6LTA1.
SMRiQ6LTA1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6LTA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALINDK VSQALEAAGA PAGSPAAVRQ SAKIQFGDYQ ANGVMGVAKK
60 70 80 90 100
LGTNPREFAQ KVIDVLDLDG IAEKVEIAGP GFINIFLDKS WLAARAEEAL
110 120 130 140 150
TDDRIGVAAE KQQNIVVDYS APNVAKEMHV GHLRSTIIGD AVVRTLEFLG
160 170 180 190 200
HNVVRANHIG DWGTQFGMLI ANLERVQNET GEVSMELADL EGFYRESKKL
210 220 230 240 250
YDEDEEFAVR ARAFVVKLQS GDEYCAEMWK KLVDVTMVQN QINYDRLNVS
260 270 280 290 300
LTRDNVMGES MYNYMLPGIV ADLKEKGLAV ESDGAQVVFL DEYKNKDGDP
310 320 330 340 350
MGVIIQKRDG GFLYTTTDIA CAKYRFEQLN ADRVLYFIDS RQHQHLMQAW
360 370 380 390 400
SIVRKAGYVP EEVTLEHHAF GMMLGKDGRP FKTRAGGTVR LADLLDESEV
410 420 430 440 450
RAAKLIEAKN PDLDTAEKDK IAKTVAMAAV KYADLSKHRT TDYIFDWDNM
460 470 480 490 500
LAFEGNTAPY MQYAYTRVAS IFKRADVNLA DLTHPIVIND EKEQALLSTL
510 520 530 540 550
LQFEEAVLNV SREGQPHLMC TYLFELAGKF SSFYEACPIL NAEEAVKQSR
560 570
LKLALLTAKT IKQGLDLLGI ETLERM
Length:576
Mass (Da):64,249
Last modified:July 5, 2004 - v1
Checksum:iBB7B31D5B0E4BDED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378666 Genomic DNA. Translation: CAG19475.1.
RefSeqiWP_011217808.1. NC_006370.1.

Genome annotation databases

EnsemblBacteriaiCAG19475; CAG19475; PBPRA1064.
KEGGippr:PBPRA1064.

Similar proteinsi

Entry informationi

Entry nameiSYR_PHOPR
AccessioniPrimary (citable) accession number: Q6LTA1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: August 30, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families