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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Photobacterium profundum (strain SS9)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:PBPRA2850
OrganismiPhotobacterium profundum (strain SS9)
Taxonomic identifieri298386 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
Proteomesi
  • UP000000593 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001877901 – 196Peptidyl-tRNA hydrolaseAdd BLAST196

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi298386.PBPRA2850

Structurei

3D structure databases

ProteinModelPortaliQ6LNA9
SMRiQ6LNA9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004796
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6LNA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNNIRLLVG LANPGAEYAK TRHNAGAWVV QELARVHNVS LREESKYFGV
60 70 80 90 100
TGRITTNGQD LRLLIPTTYM NLSGKSVAAL ANFFQIKPEE ILIAHDELDL
110 120 130 140 150
PPGVAKFKKG GGHGGHNGLR DTISKMGNNK EFYRLRVGIG HPGDKNKVAN
160 170 180 190
FVLGKAPVKE QECIDAAVDE AVRCMDILLK DGLNKAQNRL HSFKAE
Length:196
Mass (Da):21,485
Last modified:July 5, 2004 - v1
Checksum:iFC9E133C20776302
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378672 Genomic DNA Translation: CAG21217.1
RefSeqiWP_011219489.1, NC_006370.1

Genome annotation databases

EnsemblBacteriaiCAG21217; CAG21217; PBPRA2850
KEGGippr:PBPRA2850

Similar proteinsi

Entry informationi

Entry nameiPTH_PHOPR
AccessioniPrimary (citable) accession number: Q6LNA9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health