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Q6LML1

- GLSA_PHOPR

UniProt

Q6LML1 - GLSA_PHOPR

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Protein
Glutaminase
Gene
glsA, PBPRA3151
Organism
Photobacterium profundum (Photobacterium sp. (strain SS9))
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei115 – 1151Substrate By similarity
Binding sitei159 – 1591Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei190 – 1901Substrate By similarity
Binding sitei242 – 2421Substrate By similarity
Binding sitei260 – 2601Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPPRO298386-WGS:GSSB-3145-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:PBPRA3151
OrganismiPhotobacterium profundum (Photobacterium sp. (strain SS9))
Taxonomic identifieri74109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
ProteomesiUP000000593: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminaseUniRule annotation
PRO_1000048339Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi298386.PBPRA3151.

Structurei

3D structure databases

ProteinModelPortaliQ6LML1.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6LML1-1 [UniParc]FASTAAdd to Basket

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MKPTKELLAG ILDEVRPLIG QGKVADYIPA LAGISATKLG IAVCYNDGEI    50
IQAGDTQERF SIQSISKVMS LTLAMSLYEP EEIWRRVGKE PSGHAFNSMI 100
QLELENGIPR NPFINAGALV VSDLLHSRLA APQYRMLELV RKLSCNPHLT 150
YDKAVAASEM QHSDRNASIA YLMRSFGNFE NEVMPVLTNY FSYCSLNMSC 200
IDLARTFSYL ANKGLPLGAK KTIISQTQSK QMNALLATCG LYDGAGEFAY 250
RVGMPGKSGV GGGIVAIVPG EMSITVWSPE LDPSGNSLAG TAALELLAER 300
IGRSIF 306
Length:306
Mass (Da):33,101
Last modified:July 5, 2004 - v1
Checksum:i6BF7AD30710013D4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR378673 Genomic DNA. Translation: CAG21466.1.
RefSeqiYP_131268.1. NC_006370.1.

Genome annotation databases

EnsemblBacteriaiCAG21466; CAG21466; PBPRA3151.
GeneIDi3125380.
KEGGippr:PBPRA3151.
PATRICi22937363. VBIPhoPro109272_3306.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR378673 Genomic DNA. Translation: CAG21466.1 .
RefSeqi YP_131268.1. NC_006370.1.

3D structure databases

ProteinModelPortali Q6LML1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 298386.PBPRA3151.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG21466 ; CAG21466 ; PBPRA3151 .
GeneIDi 3125380.
KEGGi ppr:PBPRA3151.
PATRICi 22937363. VBIPhoPro109272_3306.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci PPRO298386-WGS:GSSB-3145-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SS9.

Entry informationi

Entry nameiGLSA_PHOPR
AccessioniPrimary (citable) accession number: Q6LML1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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