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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Photobacterium profundum (Photobacterium sp. (strain SS9))
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei515 – 5151UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPPRO298386-WGS:GSSB-3321-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PBPRA3328
OrganismiPhotobacterium profundum (Photobacterium sp. (strain SS9))
Taxonomic identifieri74109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
ProteomesiUP000000593 Componenti: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Glucose-6-phosphate isomerasePRO_0000180701Add
BLAST

Proteomic databases

PRIDEiQ6LM51.

Interactioni

Protein-protein interaction databases

STRINGi298386.PBPRA3328.

Structurei

3D structure databases

ProteinModelPortaliQ6LM51.
SMRiQ6LM51. Positions 19-550.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6LM51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKNINPTHT QAWKDLTAHY EDAQDLQLSD LFANDSERFN KFSATFGSDI
60 70 80 90 100
LLDYSKNLIT EETLTKLFAL AEQTELKAAI AEMFSGEKIN KTEDRAVLHS
110 120 130 140 150
ALRNRSNTPV VVDGEDVMPK VNAVLEKMKA FTARIVDGDW KGYTGQEITD
160 170 180 190 200
VVNVGIGGSD LGPYMVSEAL VPYKTRLNMH FVSNVDGTHI AETLKDLNPE
210 220 230 240 250
TTLFLIASKT FTTQETMTNA HSARDWFLAT AQDQAHVAKH FAALSTNVGS
260 270 280 290 300
VSEFGIDTDN MFEFWDWVGG RYSLCSAIGL SICLSIGFDN FVELLDGAHE
310 320 330 340 350
MDQHFAQAPL EENLPVILAL IGIWYNNFHG AESEAILPYD QYLHRFAAYF
360 370 380 390 400
QQGNMESNGK CVDRGGNPVD YQTGPIIWGE PGTNGQHAFY QLIHQGTKLI
410 420 430 440 450
PCDFIAPSIS HNPLTDHHPK LMANFFAQTE ALAFGKTKEQ VEAEFVAAGK
460 470 480 490 500
TLDEVKDLVP FKVFDGNRPT NSILIKQVTP KVLGSLMALY EQKIFTQGVI
510 520 530 540 550
WNIFSFDQWG VELGKQLANQ ILPELNDADS IAGHDSSTNG LINAYKQWRK
Length:550
Mass (Da):61,190
Last modified:July 5, 2004 - v1
Checksum:i20D3C88BEDBD1246
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378673 Genomic DNA. Translation: CAG21626.1.
RefSeqiYP_131428.1. NC_006370.1.

Genome annotation databases

KEGGippr:PBPRA3328.
PATRICi22937723. VBIPhoPro109272_3470.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR378673 Genomic DNA. Translation: CAG21626.1.
RefSeqiYP_131428.1. NC_006370.1.

3D structure databases

ProteinModelPortaliQ6LM51.
SMRiQ6LM51. Positions 19-550.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi298386.PBPRA3328.

Proteomic databases

PRIDEiQ6LM51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGippr:PBPRA3328.
PATRICi22937723. VBIPhoPro109272_3470.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciPPRO298386-WGS:GSSB-3321-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SS9.

Entry informationi

Entry nameiG6PI_PHOPR
AccessioniPrimary (citable) accession number: Q6LM51
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: April 1, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.