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Q6LM08

- Q6LM08_PHOPR

UniProt

Q6LM08 - Q6LM08_PHOPR

Protein

Alanine racemase

Gene

ALR

Organism
Photobacterium profundum (Photobacterium sp. (strain SS9))
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei72 – 721Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei171 – 1711SubstrateUniRule annotation
    Active sitei297 – 2971Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei345 – 3451Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPPRO298386-WGS:GSSB-3378-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:ALRImported
    Ordered Locus Names:PBPRA3385Imported
    OrganismiPhotobacterium profundum (Photobacterium sp. (strain SS9))Imported
    Taxonomic identifieri74109 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
    ProteomesiUP000000593: Chromosome 1

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei72 – 721N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi298386.PBPRA3385.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6LM08.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000279190.
    KOiK01775.
    OMAiHVANSYI.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6LM08-1 [UniParc]FASTAAdd to Basket

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    MKLKLSLVAL ALMGQTTANA APLLVDFDNN EREERVQSSN AWLEIDTQAF    50
    SGNIQLLQNQ LKADTKICAI MKADAYGNGI AGLMPSIIAN QVPCVGITSN 100
    EEARVVRKHG FIGKIMRVRA ASKNEIEGGL QYQMEELIGT KAQADQIIEI 150
    ARANGTTIPV HLALNTSGMG RNGLDLTTYE GQVEGVEIAG DPNLEIVGMM 200
    THFPNEGLDE IKRKVKRFKV ETKWLMDSTD LKRKDVTLHV ANSYITLNLP 250
    EAHLDMVRPG GMLYGDYPAT APYQRIVSFK THVASLHHFP AGSTIGYGST 300
    AVLERDSVLA NLPIGYSDGF ARSLGNKAEV LINGQRARVM GMVSMNTTMV 350
    DVTDIVDVQT NEEVVIFGRQ GFEEITGEET EEKSNRILPE HYTVWGATNP 400
    RIYR 404
    Length:404
    Mass (Da):44,408
    Last modified:July 5, 2004 - v1
    Checksum:iBC0E50D155592F87
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR378673 Genomic DNA. Translation: CAG21670.1.
    RefSeqiYP_131472.1. NC_006370.1.

    Genome annotation databases

    EnsemblBacteriaiCAG21670; CAG21670; PBPRA3385.
    GeneIDi3125459.
    KEGGippr:PBPRA3385.
    PATRICi22937837. VBIPhoPro109272_3514.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR378673 Genomic DNA. Translation: CAG21670.1 .
    RefSeqi YP_131472.1. NC_006370.1.

    3D structure databases

    ProteinModelPortali Q6LM08.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 298386.PBPRA3385.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAG21670 ; CAG21670 ; PBPRA3385 .
    GeneIDi 3125459.
    KEGGi ppr:PBPRA3385.
    PATRICi 22937837. VBIPhoPro109272_3514.

    Phylogenomic databases

    HOGENOMi HOG000279190.
    KOi K01775.
    OMAi HVANSYI.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci PPRO298386-WGS:GSSB-3378-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SS9Imported.

    Entry informationi

    Entry nameiQ6LM08_PHOPR
    AccessioniPrimary (citable) accession number: Q6LM08
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3