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Q6LM08 (Q6LM08_PHOPR) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Name:ALR EMBL CAG21670.1
Ordered Locus Names:PBPRA3385 EMBL CAG21670.1
OrganismPhotobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP] EMBL CAG21670.1
Taxonomic identifier74109 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site721Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2971Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1711Substrate By similarity HAMAP-Rule MF_01201
Binding site3451Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue721N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q6LM08 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: BC0E50D155592F87

FASTA40444,408
        10         20         30         40         50         60 
MKLKLSLVAL ALMGQTTANA APLLVDFDNN EREERVQSSN AWLEIDTQAF SGNIQLLQNQ 

        70         80         90        100        110        120 
LKADTKICAI MKADAYGNGI AGLMPSIIAN QVPCVGITSN EEARVVRKHG FIGKIMRVRA 

       130        140        150        160        170        180 
ASKNEIEGGL QYQMEELIGT KAQADQIIEI ARANGTTIPV HLALNTSGMG RNGLDLTTYE 

       190        200        210        220        230        240 
GQVEGVEIAG DPNLEIVGMM THFPNEGLDE IKRKVKRFKV ETKWLMDSTD LKRKDVTLHV 

       250        260        270        280        290        300 
ANSYITLNLP EAHLDMVRPG GMLYGDYPAT APYQRIVSFK THVASLHHFP AGSTIGYGST 

       310        320        330        340        350        360 
AVLERDSVLA NLPIGYSDGF ARSLGNKAEV LINGQRARVM GMVSMNTTMV DVTDIVDVQT 

       370        380        390        400 
NEEVVIFGRQ GFEEITGEET EEKSNRILPE HYTVWGATNP RIYR 

« Hide

References

[1]"Life at depth: Photobacterium profundum genome sequence and expression analysis."
Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G.
Science 307:1459-1461(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SS9.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR378673 Genomic DNA. Translation: CAG21670.1.
RefSeqYP_131472.1. NC_006370.1.

3D structure databases

ProteinModelPortalQ6LM08.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING298386.PBPRA3385.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG21670; CAG21670; PBPRA3385.
GeneID3125459.
KEGGppr:PBPRA3385.
PATRIC22937837. VBIPhoPro109272_3514.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000279190.
KOK01775.
OMAHVANSYI.
OrthoDBEOG6PP9NJ.
ProtClustDBPRK13340.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6LM08_PHOPR
AccessionPrimary (citable) accession number: Q6LM08
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)