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Reviewed, UniProtKB/Swiss-Prot Q6LLK0 (HEM6_PHOPR)

Last modified June 16, 2009. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: PBPRA3572
OrganismPhotobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]
Taxonomic identifier74109 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium

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Protein attributes

Sequence length301 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 301301Coproporphyrinogen-III oxidase, aerobic
PRO_0000109906

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Sequences

Sequence LengthMass (Da)Tools
Q6LLK0-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 8CB41B4D7D89CA61

FASTA30134,737
        10         20         30         40         50         60 
MEHVDKHAVK AFLLSLQDQI CQSLESQDKS AAFEQDEWQR EQGGGGRSRV LRQGSVFEQA 

        70         80         90        100        110        120 
GVNFSHVFGT KMPASATAHR PELAGRSFEA MGVSLVIHPN NPYIPTSHAN VRFFIAEKEG 

       130        140        150        160        170        180 
EAPVWWFGGG FDLTPFYPFE EDCQHWHNTA KYLCAPFGDD IYEQHKVWCD KYFFLPHRNE 

       190        200        210        220        230        240 
TRGVGGLFFD DLNEWGFEKS FAYTQAVGNG FIDGYLPIVQ RRQDTPYGER EREFQLYRRG 

       250        260        270        280        290        300 
RYVEFNLVYD RGTLFGLQSG GRTESILMSM PPLARWEYCY EPKAGSAEAD LYENYLQPRE 


W

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References

[1]"Life at depth: Photobacterium profundum genome sequence and expression analysis."
Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G.
Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CR378674 Genomic DNA. Translation: CAG21828.1.
RefSeqYP_131630.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3124200.
GenomeReviewsGene locus PBPRA3572 in contig CR354531_GR.
KEGGppr:PBPRA3572.
NMPDRfig|298386.1.peg.5748.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ6LLK0.
OMAQ6LLK0. VKAYLLD.

Enzyme and pathway databases

BioCycPPRO298386:PBPRA3572-MON.
BRENDA1.3.3.3. 263915.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_PHOPR
AccessionPrimary (citable) accession number: Q6LLK0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: July 5, 2004
Last modified: June 16, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents