Reviewed, UniProtKB/Swiss-Prot Q6LLD4 (ACKA2_PHOPR)

Names and origin

Protein names

Recommended name:
    Acetate kinase 2
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 2

Gene names

Name:	ackA2
Ordered Locus Names:	PBPRB0074

Organism

Photobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]

Taxonomic identifier

74109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase 2 HAMAP MF_00020		PRO_0000107600

Sequences

	Sequence		Length	Mass (Da)
	Q6LLD4-1 [UniParc]. Last modified March 1, 2005. Version 2. Checksum: 11D6C6BC23EEABF4	FASTA	397	42,876
	10 20 30 40 50 60 MSNSLVLVIN SGSSSLKFAL IDTVSGEATL NGIGECFGLA DANVSWKIDG KKHEFQLSDN 70 80 90 100 110 120 GNHHKQAIDR IVALLEEQGI KQDIVAVGHR VVHGGEKFTQ TVKIDETVLQ EIENLSDLAP 130 140 150 160 170 180 LHNPAHVVGM RAAIAAFPAL SQYAVFDTAF HQTMPAKAFT GAISSKLYDD YGIRRYGFHG 190 200 210 220 230 240 TSHYFVSREA AKVINKPIEK SSFISVHLGN GASVCAIKDG QSVDTSMGFT PLSGLMMGTR 250 260 270 280 290 300 CGDLDPGIIE FLLKKGWSTE QVFKELNSNS GFLGVSGLTS DCRGVIEAME EGHAGATLAF 310 320 330 340 350 360 EIFTYRVAKY IASYMVALDE LDGIIFTGGI GENSLPIRRQ ILKSLKIFGY REDEVANADA 370 380 390 RFGKGGVITQ ANTPIAMVIP TNEEWVIAKE SMALLHA

References

[1]

"Life at depth: Photobacterium profundum genome sequence and expression analysis." Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G. Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CR378675 Genomic DNA. Translation: CAG21947.1. Different initiation.
3D structure databases
ModBase	Search...
Genome annotation databases
GenomeReviews	Gene locus PBPRB0074 in contig CR354532_GR.
KEGG	ppr:PBPRB0074.
NMPDR	fig|298386.1.peg.77.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6LLD4.
Enzyme and pathway databases
BioCyc	PPRO298386:PBPRB0074-MON.
BRENDA	2.7.2.1. 263915.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA2_PHOPR

Accession

Primary (citable) accession number: Q6LLD4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	March 1, 2005
Last modified:	September 22, 2009
This is version 33 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)