SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6LL68

- BGAL_PHOPR

UniProt

Q6LL68 - BGAL_PHOPR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Beta-galactosidase

Gene
lacZ, PBPRB0034
Organism
Photobacterium profundum (Photobacterium sp. (strain SS9))
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

Cofactori

Binds 2 magnesium ions per monomer By similarity.UniRule annotation
Binds 1 sodium ion per monomer By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei99 – 991Substrate By similarity
Metal bindingi197 – 1971Sodium By similarity
Binding sitei197 – 1971Substrate By similarity
Sitei352 – 3521Transition state stabilizer By similarity
Sitei386 – 3861Transition state stabilizer By similarity
Metal bindingi411 – 4111Magnesium 1 By similarity
Metal bindingi413 – 4131Magnesium 1 By similarity
Active sitei456 – 4561Proton donor By similarity
Metal bindingi456 – 4561Magnesium 1 By similarity
Binding sitei456 – 4561Substrate By similarity
Active sitei532 – 5321Nucleophile By similarity
Metal bindingi592 – 5921Magnesium 2 By similarity
Metal bindingi596 – 5961Sodium; via carbonyl oxygen By similarity
Metal bindingi599 – 5991Sodium By similarity
Binding sitei599 – 5991Substrate By similarity
Binding sitei1004 – 10041Substrate By similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro
  3. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding, Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase (EC:3.2.1.23)
Short name:
Beta-gal
Alternative name(s):
Lactase
Gene namesi
Name:lacZ
Ordered Locus Names:PBPRB0034
OrganismiPhotobacterium profundum (Photobacterium sp. (strain SS9))
Taxonomic identifieri74109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaePhotobacterium
ProteomesiUP000000593: Chromosome 2

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10301030Beta-galactosidaseUniRule annotationPRO_0000367005Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi298386.PBPRB0034.

Structurei

3D structure databases

ProteinModelPortaliQ6LL68.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni532 – 5354Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000252443.
KOiK01190.
OMAiNPPFVPK.
OrthoDBiEOG6XWV0T.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_01687. Beta_gal.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023933. Glyco_hydro_2_beta_Galsidase.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6LL68-1 [UniParc]FASTAAdd to Basket

« Hide

MALSDIIQRR DWENPQSVNI HCLKAHSPLA SYRDINHARD GIHAQRQSLN     50
GQWKFKLFDA PEQVEGEFID VQFNDSAWGD ITVPSNWQLQ GYDKPIYANV 100
KYPFEVNPPY VPADNPTGCY RTRLTLTEAD LESTQRIIFD GVNSAFHLWC 150
NGDWVGYSQD SRLPAEFDLS QYLTAGENTL AVMVIRWSDG SYLEDQDMWW 200
LSGIFRDVTL LSKPKQCIED VFITPDLDAC YRDGSLSIVT HISAPETSQV 250
HVQLFDGSQA VTEPSIARPH NRRIDERGSY DDVVFQTLHV REPQQWTAET 300
PNLYRVVVSL LDAEGNHLES EAYQVGFRKV EVKDGQLQLN GKPLLIRGVN 350
RHEHHPELGH VMTEEDMVRD ICLMKQYNFN AVRTAHYPNH PRWYELCDQY 400
GLYVCDEANI ETHGMIPMNR LSADPQWAHA YMSRYTQMVM RDKNHPSIII 450
WSLGNESGHG SSHNAMYAWS KQFDPSRPVQ YEGGGANTTA TDIICPMYAR 500
VNTTVEDEAV PKWPIKQWIS LPNEQRPLIL CEYAHAMGNS LGNFNEYWDA 550
FREFPRLQGG FIWDWVDQGL SQWDNDGKHF WAYGGDFGDT INDRQFCING 600
LIFPDRTPHP TLEEVKFCQR MITVALTQQD KQQCHLTVTN EYVFRSTDNE 650
QLHWSVLENG VEVQSGQCTL AIDAGSQQTV DIALDFQPKA DAKYHLNTDI 700
CLISATPWAQ AGHVSATEQF TLSNTSSLTL PKISILSAPQ LSEQGRDILV 750
SNLDKKHQWQ WNVESGLLTS WMVDGQSQLL HAPEDNFFRA PLDNDIGVSE 800
IDNIDPNAWV CRWDAAGIGR WERECVSCTS ESLSQAVKVT STFAYHHNGG 850
VQAITVWTYT LDNQGEMHID VDVTLADHLP PMPRIGLELA LPLPSDNTTV 900
TWQGLGPFEN YPDRLAAARF GQHTQSLDAM HTPYIFPTDS GLRSGTQWLN 950
VGNLECTGDF LFSVSRFSQQ QLTEAKHTNE LTLEDKIYLR IDHQHMGVGG 1000
DDSWSPSVHE EFQLTDNTYR FSIMLKPRHN 1030
Length:1,030
Mass (Da):117,266
Last modified:July 5, 2004 - v1
Checksum:i6A859CAEA1AF7939
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR378675 Genomic DNA. Translation: CAG21907.1.
RefSeqiYP_131707.1. NC_006371.1.

Genome annotation databases

EnsemblBacteriaiCAG21907; CAG21907; PBPRB0034.
GeneIDi3120206.
KEGGippr:PBPRB0034.
PATRICi22938410. VBIPhoPro109272_3773.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR378675 Genomic DNA. Translation: CAG21907.1 .
RefSeqi YP_131707.1. NC_006371.1.

3D structure databases

ProteinModelPortali Q6LL68.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 298386.PBPRB0034.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAG21907 ; CAG21907 ; PBPRB0034 .
GeneIDi 3120206.
KEGGi ppr:PBPRB0034.
PATRICi 22938410. VBIPhoPro109272_3773.

Phylogenomic databases

eggNOGi COG3250.
HOGENOMi HOG000252443.
KOi K01190.
OMAi NPPFVPK.
OrthoDBi EOG6XWV0T.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_01687. Beta_gal.
InterProi IPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023933. Glyco_hydro_2_beta_Galsidase.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view ]
PRINTSi PR00132. GLHYDRLASE2.
SMARTi SM01038. Bgal_small_N. 1 hit.
[Graphical view ]
SUPFAMi SSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEi PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SS9.

Entry informationi

Entry nameiBGAL_PHOPR
AccessioniPrimary (citable) accession number: Q6LL68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi