Q6LH17 (Q6LH17_PHOPR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Ordered Locus Names:

PBPRB1551

Organism

Photobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]

Taxonomic identifier

74109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium

Protein attributes

Sequence length	403 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6LH17 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 3401098633FE6CF1	FASTA	403	43,712
	10 20 30 40 50 60 MSELYDVIII GGGAGGMSAG VYAARGKMKT LIIEEKRKAG GQAATTDEME NYPGILSATG 70 80 90 100 110 120 PELMDAFRAH CDKFGVEFTK GIVNKIDVAD DGYLKTLTTT KGEVFQAKSI IIGTGASPLI 130 140 150 160 170 180 LGVPGENEFR GKGVSYCATC DADFFEELDI VVVGSGNTAV EESLFLTKFV NKITMIVRRD 190 200 210 220 230 240 HGILAADRTA QEQAFANDKI NFVWNSVLDE ITGDELVNGV NVKNIKTGEI SHIESDGVFM 250 260 270 280 290 300 FVGTVPKTDF IKGLIDLNSH GYIVTNDKQE TNIPGIYAVG DVTEKFLRQV VTAAGDGAVA 310 320 330 340 350 360 AVAADRYIEE EDNWRKSVVD FDGTALVAFW APQNQDSIDV INQLEAQNKG QAGKNVVTID 370 380 390 400 IFKNQKIAKQ FNVSEIPVVI RFDAGQEAKR VNVKDLNELE TLY

References

[1]

"Life at depth: Photobacterium profundum genome sequence and expression analysis." Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G. Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR378679 Genomic DNA. Translation: CAG23413.1.
RefSeq	YP_133213.1. NC_006371.1.
3D structure databases
ProteinModelPortal	Q6LH17.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3120805.
GenomeReviews	Gene locus PBPRB1551 in contig CR354532_GR.
KEGG	ppr:PBPRB1551.
NMPDR	fig|298386.1.peg.1667.
PATRIC	22941784. VBIPhoPro109272_5449.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG669726.
OMA	GEEREFP.
PhylomeDB	Q6LH17.
Enzyme and pathway databases
BioCyc	PPRO298386:PBPRB1551-MONOMER.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. IPR012336. Thioredoxin-like_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6LH17_PHOPR

Accession

Primary (citable) accession number: Q6LH17

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)