Q6LG56 (UXUA_PHOPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mannonate dehydratase
EC=4.2.1.8

Alternative name(s):
D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	PBPRB1874

Organism

Photobacterium profundum (Photobacterium sp. (strain SS9)) [Complete proteome] [HAMAP]

Taxonomic identifier

74109 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Photobacterium

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 394	394	Mannonate dehydratase HAMAP MF_00106		PRO_0000170680

Sequences

	Sequence		Length	Mass (Da)
	Q6LG56 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 3FC577902993CA4C	FASTA	394	44,802
	10 20 30 40 50 60 MEQTWRWYGP NDPVSLNDIR QAGATGIVNA LHHIPNGEVW TKEEILIRKA LIEDKGLTWS 70 80 90 100 110 120 VVESVPVHEE IKTQTGNYQL WIDNYKQTLR NLAECGIDTV CYNFMPVLDW TRTDLEFEMD 130 140 150 160 170 180 DGSKALRFDQ IAFAAFELHI LKRPSAEGAY SDEEQAQAKI YFDNMSDADI AKLTGNIIAG 190 200 210 220 230 240 LPGAEEGYTL QEFQAQLDLY DGITKDKLRE HMVYFLKELM PICDANGLKM AVHPDDPPRP 250 260 270 280 290 300 ILGLPRIVST IEDIDWLTAE VPSQMNGITM CTGSYGARGD NDLVNMIRQH GDRIYFTHLR 310 320 330 340 350 360 STQREDNQLS FHEAAHLDGD VDMYNVVMEI LKEEQRRDDA GDVRLIPMRP DHGHQMLDDL 370 380 390 NKKTNPGYSA IGRLKGLAEV RGLEMALKRA FFTK

References

[1]

"Life at depth: Photobacterium profundum genome sequence and expression analysis." Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M., Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C., Bartlett D.H., Valle G. Science 307:1459-1461(2005) [PubMed: 15746425] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SS9.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR378680 Genomic DNA. Translation: CAG23724.1.
RefSeq	YP_133524.1. NC_006371.1.
3D structure databases
ProteinModelPortal	Q6LG56.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3120501.
GenomeReviews	Gene locus PBPRB1874 in contig CR354532_GR.
KEGG	ppr:PBPRB1874.
NMPDR	fig|298386.1.peg.1995.
PATRIC	22942504. VBIPhoPro109272_5795.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG585927.
OMA	VHEEIKT.
PhylomeDB	Q6LG56.
ProtClustDB	PRK03906.
Enzyme and pathway databases
BioCyc	PPRO298386:PBPRB1874-MONOMER.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KO	K01686.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR00695. UxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_PHOPR

Accession

Primary (citable) accession number: Q6LG56

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program