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Protein

Annexin

Gene

ANXA4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium, Calcium/phospholipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:ANXA4Imported
Synonyms:PIG28Imported
ORF Names:hCG_39482Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000196975.15.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24832.

PTM / Processingi

Proteomic databases

MaxQBiQ6LES2.

Expressioni

Gene expression databases

BgeeiENSG00000196975.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PADI4Q9UM075EBI-10250835,EBI-1042511

Protein-protein interaction databases

IntActiQ6LES2. 1 interactor.
MINTiMINT-4998726.

Structurei

3D structure databases

SMRiQ6LES2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
HOGENOMiHOG000158803.
HOVERGENiHBG061815.
KOiK17093.
OMAiILCGGDD.
OrthoDBiEOG091G0H6H.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiView protein in InterPro
IPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR002391. ANX4.
PANTHERiPTHR10502:SF166. PTHR10502:SF166. 1 hit.
PfamiView protein in Pfam
PF00191. Annexin. 4 hits.
PRINTSiPR00196. ANNEXIN.
SMARTiView protein in SMART
SM00335. ANX. 4 hits.
PROSITEiView protein in PROSITE
PS00223. ANNEXIN. 3 hits.

Sequencei

Sequence statusi: Fragment.

Q6LES2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMATKGGTV KAASGFNAME DAQTLRKAMK GLGTDEDAII SVLAYRNTAQ
60 70 80 90 100
RQEIRTAYKS TIGRDLIDDL KSELSGNFEQ VIVGMMTPTV LYDVQELRRA
110 120 130 140 150
MKGAGTDEGC LIEILASRTP EEIRRISQTY QQQYGRSLED DIRSDTSFMF
160 170 180 190 200
QRVLVSLSAG GRDEGNYLDD ALVRQDAQDL YEAGEKKWGT DEVKFLTVLC
210 220 230 240 250
SRNRNHLLHV FDEYKRISQK DIEQSIKSET SGSFEDALLA IVKCMRNKSA
260 270 280 290 300
YFAEKLYKSM KGLGTDDNTL IRVMVSRAEI DMLDIRAHFK RLYGKSLYSF
310 320
IKGDTSGDYR KVLLVLCGGD D
Length:321
Mass (Da):36,085
Last modified:July 5, 2004 - v1
Checksum:i59CFD538867E76B5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei321Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY453398 mRNA. Translation: AAS47515.1.
AC019206 Genomic DNA. Translation: AAY14864.1.
AK315511 mRNA. Translation: BAG37892.1.
CR407681 mRNA. Translation: CAG28609.1.
CH471053 Genomic DNA. Translation: EAW99844.1.
RefSeqiNP_001144.1. NM_001153.4.
NP_001307627.1. NM_001320698.1.
XP_016859432.1. XM_017003943.1.
UniGeneiHs.422986.

Genome annotation databases

GeneIDi307.
KEGGihsa:307.
UCSCiuc002sfr.5. human.

Similar proteinsi

Entry informationi

Entry nameiQ6LES2_HUMAN
AccessioniPrimary (citable) accession number: Q6LES2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 27, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.