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Protein

Annexin

Gene

ANXA4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalcium, Calcium/phospholipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:ANXA4Imported
Synonyms:PIG28Imported
ORF Names:hCG_39482Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000196975.15

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24832

PTM / Processingi

Proteomic databases

MaxQBiQ6LES2
PRIDEiQ6LES2

Expressioni

Gene expression databases

BgeeiENSG00000196975
ExpressionAtlasiQ6LES2 baseline and differential

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PADI4Q9UM075EBI-10250835,EBI-1042511

Protein-protein interaction databases

IntActiQ6LES2, 1 interactor

Structurei

3D structure databases

SMRiQ6LES2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0819 Eukaryota
ENOG410XPUN LUCA
HOGENOMiHOG000158803
HOVERGENiHBG061815
KOiK17093
OMAiRANFKRL
OrthoDBiEOG091G0H6H

Family and domain databases

Gene3Di1.10.220.10, 4 hits
InterProiView protein in InterPro
IPR001464 Annexin
IPR018502 Annexin_repeat
IPR018252 Annexin_repeat_CS
IPR037104 Annexin_sf
IPR002391 ANX4
PANTHERiPTHR10502:SF28 PTHR10502:SF28, 1 hit
PfamiView protein in Pfam
PF00191 Annexin, 4 hits
PRINTSiPR00196 ANNEXIN
SMARTiView protein in SMART
SM00335 ANX, 4 hits
PROSITEiView protein in PROSITE
PS00223 ANNEXIN, 3 hits

Sequencei

Sequence statusi: Fragment.

Q6LES2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMATKGGTV KAASGFNAME DAQTLRKAMK GLGTDEDAII SVLAYRNTAQ
60 70 80 90 100
RQEIRTAYKS TIGRDLIDDL KSELSGNFEQ VIVGMMTPTV LYDVQELRRA
110 120 130 140 150
MKGAGTDEGC LIEILASRTP EEIRRISQTY QQQYGRSLED DIRSDTSFMF
160 170 180 190 200
QRVLVSLSAG GRDEGNYLDD ALVRQDAQDL YEAGEKKWGT DEVKFLTVLC
210 220 230 240 250
SRNRNHLLHV FDEYKRISQK DIEQSIKSET SGSFEDALLA IVKCMRNKSA
260 270 280 290 300
YFAEKLYKSM KGLGTDDNTL IRVMVSRAEI DMLDIRAHFK RLYGKSLYSF
310 320
IKGDTSGDYR KVLLVLCGGD D
Length:321
Mass (Da):36,085
Last modified:July 5, 2004 - v1
Checksum:i59CFD538867E76B5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei321Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY453398 mRNA Translation: AAS47515.1
AC019206 Genomic DNA Translation: AAY14864.1
AK315511 mRNA Translation: BAG37892.1
CR407681 mRNA Translation: CAG28609.1
CH471053 Genomic DNA Translation: EAW99844.1
RefSeqiNP_001144.1, NM_001153.4
NP_001307627.1, NM_001320698.1
XP_016859432.1, XM_017003943.1
UniGeneiHs.422986

Genome annotation databases

GeneIDi307
KEGGihsa:307
UCSCiuc002sfr.5 human

Similar proteinsi

Entry informationi

Entry nameiQ6LES2_HUMAN
AccessioniPrimary (citable) accession number: Q6LES2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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