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Unreviewed, UniProtKB/TrEMBL Q6LEQ2 (Q6LEQ2_RAT)

Last modified January 19, 2010. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Cytochrome P450 3A EMBL BAA06233.1
Gene names
Name: Cyp3a3 RGD 2478
Synonyms: CYP EMBL BAA06233.1
OrganismRattus norvegicus (Rat) EMBL BAA06233.1
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

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Protein attributes

Sequence length502 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Sequence similarities

Belongs to the cytochrome P450 family.

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Sequences

Sequence LengthMass (Da)Tools
Q6LEQ2-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 274AF811DD7C6A4B

FASTA50257,724
        10         20         30         40         50         60 
MDLLSALTLE TWVLLAVVLV LLYGFGTRTH GLFKKQGIPG PKPLPFFGTV LNYYMGLWKF 

        70         80         90        100        110        120 
DVECHKKYGK IWGLFDGQMP LFAITDTEMI KNVLVKECFS VFTNRRYFGP VGIMGKAISV 

       130        140        150        160        170        180 
SKDEEWKRYR ALLSPTFTSG RLKEMFPVIE QYGDILVKYL RQEKGKPVPV KEVFGAYSMD 

       190        200        210        220        230        240 
VITSTSFGVN VDSLNNPKDP FVEKAKKLLR IDFFDPLFLS VVLFPFLTPV YEMLNICMFP 

       250        260        270        280        290        300 
KDSIEFFKKF VYRMKETRLD SVQKHRVDFL QLMMNAHNDS KDKESHTALS DMEITAQSII 

       310        320        330        340        350        360 
FIFAGYEPTS STLSFVLHSL ATHPDTQKKL QEEIDRALPN KAPPTYDTVM EMEYLDMVLN 

       370        380        390        400        410        420 
ETLRLYPIGN RLERVCKKDV EINGVFMPKG SVVMIPSYAL HRDPQHWPEP EEFRPERFSK 

       430        440        450        460        470        480 
ENKGSIDPYV YLPFGNGPRN CIGMRFALMN MKLALTKVLQ NFSFQPCKET QIPLKLSRQG 

       490        500 
LLQPTKPIIL KVVPRDEIIT GS

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References

[1]"cDNA cloning and characterization of a novel member of steroid-induced cytochrome P450 3A in rats."
Kirita S., Matsubara T.
Arch. Biochem. Biophys. 307:253-258(1993) [PubMed: 8274011] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Sprague-Dawley EMBL BAA06233.1.
Tissue: Liver EMBL BAA06233.1.
[2]"A major glucocorticoid-inducible P450 in rat liver is not P450 3A1."
Komori M., Oda Y.
J. Biochem. 116:114-120(1994) [PubMed: 7528203] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Sprague-Dawley EMBL BAA06233.1.
Tissue: Liver EMBL BAA06233.1.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		D29967 mRNA. Translation: BAA06233.1.
IPIIPI00324932.
UniGeneRn.91120

3D structure databases

SMRQ6LEQ2. Positions 30-495.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6LEQ2.

Proteomic databases

PRIDEQ6LEQ2.

Genome annotation databases

EnsemblENSRNOT00000051244; ENSRNOP00000041138; ENSRNOG00000032560; Rattus norvegicus. [Genome view]
UCSCNM_013105. rat.

Phylogenomic databases

HOVERGENQ6LEQ2.
InParanoidQ6LEQ2.

Gene expression databases

ArrayExpressQ6LEQ2.
GenevestigatorQ6LEQ2.

Family and domain databases

InterProIPR001128. Cyt_P450.
IPR017973. Cyt_P450_C.
IPR017972. Cyt_P450_CS.
IPR008072. Cyt_P450_E_CYP3A.
IPR002402. Cyt_P450_E_grp-II.
[Graphical view]
Gene3DG3DSA:1.10.630.10. Cyt_P450. 1 hit.
PANTHERPTHR19383. Cyt_P450. 1 hit.
PfamPF00067. p450. 1 hit.
[Graphical view]
PRINTSPR00464. EP450II.
PR01689. EP450IICYP3A.
PR00385. P450.
PROSITEPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ6LEQ2_RAT
AccessionPrimary (citable) accession number: Q6LEQ2
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 19, 2010
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information