ID   Q6LEE2_HUMAN            Unreviewed;        43 AA.
AC   Q6LEE2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=4a-carbinolamine dehydratase {ECO:0000313|EMBL:AAA35670.1};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAA35670.1};
RN   [1] {ECO:0000313|EMBL:AAA35670.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Blood {ECO:0000313|EMBL:AAA35670.1};
RX   PubMed=8352282;
RA   Citron B.A., Kaufman S., Milstien S., Naylor E.W., Greene C.L., Davis M.D.;
RT   "Mutation in the 4a-carbinolamine dehydratase gene leads to mild
RT   hyperphenylalaninemia with defective cofactor metabolism.";
RL   Am. J. Hum. Genet. 53:768-774(1993).
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DR   EMBL; L15410; AAA35670.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6LEE2; -.
DR   PeptideAtlas; Q6LEE2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1360.20; Transcriptional coactivator/pterin dehydratase; 1.
DR   InterPro; IPR036428; PCD_sf.
DR   SUPFAM; SSF55248; PCD-like; 1.
PE   4: Predicted;
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAA35670.1"
FT   NON_TER         43
FT                   /evidence="ECO:0000313|EMBL:AAA35670.1"
SQ   SEQUENCE   43 AA;  5111 MW;  AF402223C50AF4EF CRC64;
     GKAHRLSAEE RDQLLPNLRA VGWNELEGRD AIFKQFHFKD FNR
//