Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.





(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Submitted name:




Mus musculus (Mouse)
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli


GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. core promoter sequence-specific DNA binding Source: Ensembl
  3. DNA binding Source: MGI
  4. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: Ensembl
  5. sequence-specific DNA binding Source: MGI
  6. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. cell differentiation Source: MGI
  2. central nervous system development Source: Ensembl
  3. detection of glucose Source: Ensembl
  4. digestive tract development Source: MGI
  5. endocrine pancreas development Source: MGI
  6. exocrine pancreas development Source: MGI
  7. glucose homeostasis Source: MGI
  8. glucose metabolic process Source: MGI
  9. insulin secretion Source: Ensembl
  10. liver development Source: MGI
  11. morphogenesis of embryonic epithelium Source: MGI
  12. negative regulation of cell proliferation Source: MGI
  13. negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Source: MGI
  14. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  15. negative regulation of type B pancreatic cell apoptotic process Source: MGI
  16. nitric oxide mediated signal transduction Source: Ensembl
  17. organ regeneration Source: Ensembl
  18. organ senescence Source: Ensembl
  19. pancreas development Source: MGI
  20. positive regulation of cell death Source: Ensembl
  21. positive regulation of cell proliferation Source: MGI
  22. positive regulation of DNA binding Source: Ensembl
  23. positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: MGI
  24. positive regulation of transcription, DNA-templated Source: MGI
  25. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  26. regulation of cell proliferation Source: MGI
  27. regulation of transcription from RNA polymerase II promoter Source: MGI
  28. response to chlorate Source: Ensembl
  29. response to cytokine Source: Ensembl
  30. response to drug Source: Ensembl
  31. response to fatty acid Source: Ensembl
  32. response to glucocorticoid Source: Ensembl
  33. response to iron(II) ion Source: Ensembl
  34. response to leucine Source: Ensembl
  35. response to nicotine Source: Ensembl
  36. response to vitamin Source: Ensembl
  37. response to wounding Source: Ensembl
  38. smoothened signaling pathway Source: Ensembl
  39. stem cell differentiation Source: Ensembl
  40. transdifferentiation Source: Ensembl
  41. type B pancreatic cell differentiation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Gene namesi
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:102851. Pdx1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. intracellular Source: MGI
  3. nuclear speck Source: MGI
  4. nucleus Source: MGI
Complete GO annotation...


Gene expression databases

ExpressionAtlasiQ6LEB3. baseline and differential.

Family & Domainsi

Keywords - Domaini


Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.


Sequence statusi: Fragment.

Q6LEB3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20 
Mass (Da):3,311
Last modified:July 5, 2004 - v1

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei27 – 271Imported

Sequence databases

Select the link destinations:
Links Updated
L26239 mRNA. Translation: AAA53037.1.


Sequence databases

Select the link destinations:
Links Updated
L26239 mRNA. Translation: AAA53037.1 .
UniGenei Mm.389714.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:102851. Pdx1.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q6LEB3.
ExpressionAtlasi Q6LEB3. baseline and differential.
Genevestigatori Q6LEB3.

Family and domain databases

Gene3Di 1 hit.
InterProi IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
ProtoNeti Search...


  1. "Unpublished."
    Palis J.
    Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases
    Strain: CD-1Imported.
    Tissue: Early somite stage visceral yolk sacImported.

Entry informationi

Entry nameiQ6LEB3_MOUSE
AccessioniPrimary (citable) accession number: Q6LEB3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 7, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.