Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6LDV5

- Q6LDV5_RAT

UniProt

Q6LDV5 - Q6LDV5_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Rat 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase

Gene

Pfkfb1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. 6-phosphofructo-2-kinase activity Source: InterPro
  2. ATP binding Source: InterPro
  3. fructose-2,6-bisphosphate 2-phosphatase activity Source: Ensembl

GO - Biological processi

  1. fructose 2,6-bisphosphate metabolic process Source: Ensembl
  2. fructose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Rat 6-phosphofructo 2-kinase/fructose 2,6-bisphosphataseImported
Gene namesi
Name:Pfkfb1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3307. Pfkfb1.

Subcellular locationi

GO - Cellular componenti

  1. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ6LDV5. baseline and differential.
GenevestigatoriQ6LDV5.

Structurei

3D structure databases

ProteinModelPortaliQ6LDV5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG005628.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003094. 6Pfruct_kin.
IPR013079. 6Phosfructo_kin.
IPR016260. Bifunct_6PFK/fruc_bisP_Ptase.
IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR027417. P-loop_NTPase.
IPR001345. PG/BPGM_mutase_AS.
[Graphical view]
PANTHERiPTHR10606. PTHR10606. 1 hit.
PfamiPF01591. 6PF2K. 1 hit.
PF00300. His_Phos_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000709. 6PFK_2-Ptase. 1 hit.
PRINTSiPR00991. 6PFRUCTKNASE.
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF53254. SSF53254. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6LDV5 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
AENIKQVKLG SPDYIDCDQE KVLEDFLKRI ECYEINYQPL DEELDSHLSY
60 70 80 90 100
IKIFDVGTRY MVNRVQDHVQ SRTAYYLMNI HVTPRSIYLC RHGESELNLR
110 120 130 140 150
GRIGGDSGLS ARGKQYAYAL ANFIRSQGIS SLKVWTSHMK RTIQTAEALG
160 170 180 190 200
VPYEQWKALN EIDAGVCEEM TYEEIQEHYP EEFALRDQDK YRYRYPKGES
210 220 230 240 250
YEDLVQRLEP VIMELERQEN VLVICHQAVM RCLLAYFLDK SSDELPYLKC
260 270 280 290 300
PLHTVLKLTP VAYGCRVESI YLNVEAVNTH RDKPENVDIT REAEEALDTV

PAHY
Length:304
Mass (Da):35,404
Last modified:July 5, 2004 - v1
Checksum:i5D64BBEF657DF00F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M15685 mRNA. Translation: AAA40624.1.
UniGeneiRn.10115.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M15685 mRNA. Translation: AAA40624.1 .
UniGenei Rn.10115.

3D structure databases

ProteinModelPortali Q6LDV5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 3307. Pfkfb1.

Phylogenomic databases

HOVERGENi HBG005628.

Gene expression databases

ExpressionAtlasi Q6LDV5. baseline and differential.
Genevestigatori Q6LDV5.

Family and domain databases

Gene3Di 3.40.50.1240. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR003094. 6Pfruct_kin.
IPR013079. 6Phosfructo_kin.
IPR016260. Bifunct_6PFK/fruc_bisP_Ptase.
IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR027417. P-loop_NTPase.
IPR001345. PG/BPGM_mutase_AS.
[Graphical view ]
PANTHERi PTHR10606. PTHR10606. 1 hit.
Pfami PF01591. 6PF2K. 1 hit.
PF00300. His_Phos_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF000709. 6PFK_2-Ptase. 1 hit.
PRINTSi PR00991. 6PFRUCTKNASE.
SMARTi SM00855. PGAM. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF53254. SSF53254. 1 hit.
PROSITEi PS00175. PG_MUTASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation of a cDNA clone for rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase."
    Colosa A.D., Lively M.O., El-Maghrabi M.R., Pilkis S.J.
    Biochem. Biophys. Res. Commun. 143:1092-1098(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6LDV5_RAT
AccessioniPrimary (citable) accession number: Q6LDV5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)