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Q6LDV5

- Q6LDV5_RAT

UniProt

Q6LDV5 - Q6LDV5_RAT

Protein
Submitted name:

Rat 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase

Gene

Pfkfb1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 6-phosphofructo-2-kinase activity Source: InterPro
    2. ATP binding Source: InterPro
    3. fructose-2,6-bisphosphate 2-phosphatase activity Source: Ensembl

    GO - Biological processi

    1. fructose 2,6-bisphosphate metabolic process Source: Ensembl
    2. fructose metabolic process Source: InterPro

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Rat 6-phosphofructo 2-kinase/fructose 2,6-bisphosphataseImported
    Gene namesi
    Name:Pfkfb1Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi3307. Pfkfb1.

    Subcellular locationi

    GO - Cellular componenti

    1. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriQ6LDV5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6LDV5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG005628.
    InParanoidiQ6LDV5.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR003094. 6Pfruct_kin.
    IPR013079. 6Phosfructo_kin.
    IPR016260. Bifunct_6PFK/fruc_bisP_Ptase.
    IPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    IPR027417. P-loop_NTPase.
    IPR001345. PG/BPGM_mutase_AS.
    [Graphical view]
    PANTHERiPTHR10606. PTHR10606. 1 hit.
    PfamiPF01591. 6PF2K. 1 hit.
    PF00300. His_Phos_1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000709. 6PFK_2-Ptase. 1 hit.
    PRINTSiPR00991. 6PFRUCTKNASE.
    SMARTiSM00855. PGAM. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF53254. SSF53254. 1 hit.
    PROSITEiPS00175. PG_MUTASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6LDV5-1 [UniParc]FASTAAdd to Basket

    « Hide

    AENIKQVKLG SPDYIDCDQE KVLEDFLKRI ECYEINYQPL DEELDSHLSY    50
    IKIFDVGTRY MVNRVQDHVQ SRTAYYLMNI HVTPRSIYLC RHGESELNLR 100
    GRIGGDSGLS ARGKQYAYAL ANFIRSQGIS SLKVWTSHMK RTIQTAEALG 150
    VPYEQWKALN EIDAGVCEEM TYEEIQEHYP EEFALRDQDK YRYRYPKGES 200
    YEDLVQRLEP VIMELERQEN VLVICHQAVM RCLLAYFLDK SSDELPYLKC 250
    PLHTVLKLTP VAYGCRVESI YLNVEAVNTH RDKPENVDIT REAEEALDTV 300
    PAHY 304
    Length:304
    Mass (Da):35,404
    Last modified:July 5, 2004 - v1
    Checksum:i5D64BBEF657DF00F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M15685 mRNA. Translation: AAA40624.1.
    UniGeneiRn.10115.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M15685 mRNA. Translation: AAA40624.1 .
    UniGenei Rn.10115.

    3D structure databases

    ProteinModelPortali Q6LDV5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 3307. Pfkfb1.

    Phylogenomic databases

    HOVERGENi HBG005628.
    InParanoidi Q6LDV5.

    Gene expression databases

    Genevestigatori Q6LDV5.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR003094. 6Pfruct_kin.
    IPR013079. 6Phosfructo_kin.
    IPR016260. Bifunct_6PFK/fruc_bisP_Ptase.
    IPR013078. His_Pase_superF_clade-1.
    IPR029033. His_PPase_superfam.
    IPR027417. P-loop_NTPase.
    IPR001345. PG/BPGM_mutase_AS.
    [Graphical view ]
    PANTHERi PTHR10606. PTHR10606. 1 hit.
    Pfami PF01591. 6PF2K. 1 hit.
    PF00300. His_Phos_1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000709. 6PFK_2-Ptase. 1 hit.
    PRINTSi PR00991. 6PFRUCTKNASE.
    SMARTi SM00855. PGAM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF53254. SSF53254. 1 hit.
    PROSITEi PS00175. PG_MUTASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation of a cDNA clone for rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase."
      Colosa A.D., Lively M.O., El-Maghrabi M.R., Pilkis S.J.
      Biochem. Biophys. Res. Commun. 143:1092-1098(1987) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6LDV5_RAT
    AccessioniPrimary (citable) accession number: Q6LDV5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)