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Submitted name:

Rat pre-pro-insulin-like growth factor



Rattus norvegicus (Rat)
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Biological processi

    1. blood vessel remodeling Source: Ensembl
    2. bone mineralization involved in bone maturation Source: Ensembl
    3. branching morphogenesis of an epithelial tube Source: Ensembl
    4. chondroitin sulfate proteoglycan biosynthetic process Source: Ensembl
    5. exocrine pancreas development Source: Ensembl
    6. extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
    7. glial cell differentiation Source: Ensembl
    8. inner ear development Source: Ensembl
    9. insulin-like growth factor receptor signaling pathway Source: Ensembl
    10. lung alveolus development Source: Ensembl
    11. lung lobe morphogenesis Source: Ensembl
    12. lung vasculature development Source: Ensembl
    13. mammary gland development Source: Ensembl
    14. multicellular organism growth Source: Ensembl
    15. muscle hypertrophy Source: Ensembl
    16. myoblast differentiation Source: Ensembl
    17. myoblast proliferation Source: Ensembl
    18. myotube cell development Source: Ensembl
    19. negative regulation of androgen receptor signaling pathway Source: Ensembl
    20. negative regulation of cell proliferation Source: Ensembl
    21. negative regulation of ERK1 and ERK2 cascade Source: Ensembl
    22. negative regulation of extrinsic apoptotic signaling pathway Source: Ensembl
    23. negative regulation of smooth muscle cell apoptotic process Source: Ensembl
    24. phosphatidylinositol-mediated signaling Source: Ensembl
    25. positive regulation of activated T cell proliferation Source: Ensembl
    26. positive regulation of calcineurin-NFAT signaling cascade Source: Ensembl
    27. positive regulation of cardiac muscle hypertrophy Source: Ensembl
    28. positive regulation of cerebellar granule cell precursor proliferation Source: Ensembl
    29. positive regulation of DNA binding Source: Ensembl
    30. positive regulation of epithelial cell proliferation Source: Ensembl
    31. positive regulation of fibroblast proliferation Source: Ensembl
    32. positive regulation of glucose import Source: Ensembl
    33. positive regulation of glycogen biosynthetic process Source: Ensembl
    34. positive regulation of glycolytic process Source: Ensembl
    35. positive regulation of insulin-like growth factor receptor signaling pathway Source: Ensembl
    36. positive regulation of MAPK cascade Source: Ensembl
    37. positive regulation of mitosis Source: Ensembl
    38. positive regulation of myoblast proliferation Source: Ensembl
    39. positive regulation of osteoblast differentiation Source: Ensembl
    40. positive regulation of phosphatidylinositol 3-kinase signaling Source: Ensembl
    41. positive regulation of protein import into nucleus, translocation Source: Ensembl
    42. positive regulation of protein kinase B signaling Source: Ensembl
    43. positive regulation of Ras protein signal transduction Source: Ensembl
    44. positive regulation of smooth muscle cell migration Source: Ensembl
    45. positive regulation of smooth muscle cell proliferation Source: Ensembl
    46. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    47. positive regulation of tyrosine phosphorylation of Stat5 protein Source: Ensembl
    48. prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Source: Ensembl
    49. prostate gland growth Source: Ensembl
    50. prostate gland stromal morphogenesis Source: Ensembl
    51. regulation of establishment or maintenance of cell polarity Source: Ensembl
    52. regulation of multicellular organism growth Source: Ensembl
    53. skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration Source: Ensembl
    54. Type II pneumocyte differentiation Source: Ensembl
    55. Type I pneumocyte differentiation Source: Ensembl
    56. water homeostasis Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Rat pre-pro-insulin-like growth factorImported
    Gene namesi
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi2868. Igf1.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl


    Gene expression databases


    Family & Domainsi

    Phylogenomic databases



    Sequence statusi: Fragment.

    Q6LDU6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKISSLPTQ LFKICLCDFL KIKIHIM                            27
    Mass (Da):3,122
    Last modified:July 5, 2004 - v1

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei27 – 271Imported

    Sequence databases

    Select the link destinations:
    Links Updated
    M17594 mRNA. Translation: AAA41390.1.


    Sequence databases

    Select the link destinations:
    Links Updated
    M17594 mRNA. Translation: AAA41390.1 .
    UniGenei Rn.201887.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 2868. Igf1.

    Phylogenomic databases

    HOGENOMi HOG000233362.
    InParanoidi Q6LDU6.

    Gene expression databases

    ArrayExpressi Q6LDU6.
    Genevestigatori Q6LDU6.

    Family and domain databases

    ProtoNeti Search...


    1. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6LDU6_RAT
    AccessioniPrimary (citable) accession number: Q6LDU6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)