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Q6LDU6

- Q6LDU6_RAT

UniProt

Q6LDU6 - Q6LDU6_RAT

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Protein
Submitted name:

Rat pre-pro-insulin-like growth factor

Gene

Igf1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. blood vessel remodeling Source: Ensembl
  2. bone mineralization involved in bone maturation Source: Ensembl
  3. branching morphogenesis of an epithelial tube Source: Ensembl
  4. cell activation Source: Ensembl
  5. chondroitin sulfate proteoglycan biosynthetic process Source: Ensembl
  6. exocrine pancreas development Source: Ensembl
  7. extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
  8. glial cell differentiation Source: Ensembl
  9. inner ear development Source: Ensembl
  10. insulin-like growth factor receptor signaling pathway Source: Ensembl
  11. lung alveolus development Source: Ensembl
  12. lung lobe morphogenesis Source: Ensembl
  13. lung vasculature development Source: Ensembl
  14. mammary gland development Source: Ensembl
  15. multicellular organism growth Source: Ensembl
  16. muscle hypertrophy Source: Ensembl
  17. myoblast differentiation Source: Ensembl
  18. myoblast proliferation Source: Ensembl
  19. myotube cell development Source: Ensembl
  20. negative regulation of androgen receptor signaling pathway Source: Ensembl
  21. negative regulation of cell proliferation Source: Ensembl
  22. negative regulation of ERK1 and ERK2 cascade Source: Ensembl
  23. negative regulation of extrinsic apoptotic signaling pathway Source: Ensembl
  24. negative regulation of smooth muscle cell apoptotic process Source: Ensembl
  25. phosphatidylinositol-mediated signaling Source: Ensembl
  26. positive regulation of activated T cell proliferation Source: Ensembl
  27. positive regulation of calcineurin-NFAT signaling cascade Source: Ensembl
  28. positive regulation of cardiac muscle hypertrophy Source: Ensembl
  29. positive regulation of cerebellar granule cell precursor proliferation Source: Ensembl
  30. positive regulation of DNA binding Source: Ensembl
  31. positive regulation of epithelial cell proliferation Source: Ensembl
  32. positive regulation of fibroblast proliferation Source: Ensembl
  33. positive regulation of glucose import Source: Ensembl
  34. positive regulation of glycogen biosynthetic process Source: Ensembl
  35. positive regulation of glycolytic process Source: Ensembl
  36. positive regulation of insulin-like growth factor receptor signaling pathway Source: Ensembl
  37. positive regulation of MAPK cascade Source: Ensembl
  38. positive regulation of mitosis Source: Ensembl
  39. positive regulation of myoblast proliferation Source: Ensembl
  40. positive regulation of osteoblast differentiation Source: Ensembl
  41. positive regulation of phosphatidylinositol 3-kinase signaling Source: Ensembl
  42. positive regulation of protein import into nucleus, translocation Source: Ensembl
  43. positive regulation of protein kinase B signaling Source: Ensembl
  44. positive regulation of Ras protein signal transduction Source: Ensembl
  45. positive regulation of smooth muscle cell migration Source: Ensembl
  46. positive regulation of smooth muscle cell proliferation Source: Ensembl
  47. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  48. positive regulation of tyrosine phosphorylation of Stat5 protein Source: Ensembl
  49. prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Source: Ensembl
  50. prostate gland growth Source: Ensembl
  51. prostate gland stromal morphogenesis Source: Ensembl
  52. regulation of establishment or maintenance of cell polarity Source: Ensembl
  53. regulation of multicellular organism growth Source: Ensembl
  54. skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration Source: Ensembl
  55. Type II pneumocyte differentiation Source: Ensembl
  56. Type I pneumocyte differentiation Source: Ensembl
  57. water homeostasis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Rat pre-pro-insulin-like growth factorImported
Gene namesi
Name:Igf1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2868. Igf1.

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ6LDU6. baseline and differential.
GenevestigatoriQ6LDU6.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000233362.

Sequencei

Sequence statusi: Fragment.

Q6LDU6 [UniParc]FASTAAdd to Basket

« Hide

        10         20
MGKISSLPTQ LFKICLCDFL KIKIHIM
Length:27
Mass (Da):3,122
Last modified:July 5, 2004 - v1
Checksum:iAC140DCF34E60929
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei27 – 271Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M17594 mRNA. Translation: AAA41390.1.
UniGeneiRn.201887.
Rn.228346.
Rn.6282.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M17594 mRNA. Translation: AAA41390.1 .
UniGenei Rn.201887.
Rn.228346.
Rn.6282.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 2868. Igf1.

Phylogenomic databases

HOGENOMi HOG000233362.

Gene expression databases

ExpressionAtlasi Q6LDU6. baseline and differential.
Genevestigatori Q6LDU6.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6LDU6_RAT
AccessioniPrimary (citable) accession number: Q6LDU6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)