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Q6LD41

- Q6LD41_HUMAN

UniProt

Q6LD41 - Q6LD41_HUMAN

Protein
Submitted name:

Insulin-like growth factor-I

Gene

IGF1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. blood vessel remodeling Source: Ensembl
    2. branching morphogenesis of an epithelial tube Source: Ensembl
    3. cell development Source: Ensembl
    4. chondroitin sulfate proteoglycan biosynthetic process Source: Ensembl
    5. exocrine pancreas development Source: Ensembl
    6. extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
    7. glial cell differentiation Source: Ensembl
    8. inner ear development Source: Ensembl
    9. insulin-like growth factor receptor signaling pathway Source: Ensembl
    10. lung alveolus development Source: Ensembl
    11. lung lobe morphogenesis Source: Ensembl
    12. lung vasculature development Source: Ensembl
    13. mammary gland development Source: Ensembl
    14. multicellular organism growth Source: Ensembl
    15. negative regulation of androgen receptor signaling pathway Source: Ensembl
    16. negative regulation of apoptotic process Source: Ensembl
    17. negative regulation of cell proliferation Source: Ensembl
    18. negative regulation of ERK1 and ERK2 cascade Source: Ensembl
    19. positive regulation of cerebellar granule cell precursor proliferation Source: Ensembl
    20. positive regulation of myoblast proliferation Source: Ensembl
    21. positive regulation of phosphatidylinositol 3-kinase signaling Source: Ensembl
    22. positive regulation of protein kinase B signaling Source: Ensembl
    23. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    24. prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Source: Ensembl
    25. prostate gland growth Source: Ensembl
    26. prostate gland stromal morphogenesis Source: Ensembl
    27. regulation of establishment or maintenance of cell polarity Source: Ensembl
    28. regulation of protein phosphorylation Source: Ensembl
    29. Type II pneumocyte differentiation Source: Ensembl
    30. Type I pneumocyte differentiation Source: Ensembl
    31. water homeostasis Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Insulin-like growth factor-IImported
    Gene namesi
    Name:IGF1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ6LD41.
    BgeeiQ6LD41.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000233362.

    Sequencei

    Sequence statusi: Fragment.

    Q6LD41-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGKISSLPTQ LFKCCFCDFL K                                  21
    Length:21
    Mass (Da):2,410
    Last modified:July 5, 2004 - v1
    Checksum:i5B299F1B0919B084
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei21 – 211Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S85346 Genomic DNA. Translation: AAB21519.1.
    UniGeneiHs.160562.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S85346 Genomic DNA. Translation: AAB21519.1 .
    UniGenei Hs.160562.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000233362.

    Miscellaneous databases

    ChiTaRSi IGF1. human.

    Gene expression databases

    ArrayExpressi Q6LD41.
    Bgeei Q6LD41.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Structure and function of a human insulin-like growth factor-I gene promoter."
      Kim S.W., Lajara R., Rotwein P.
      Mol. Endocrinol. 5:1964-1972(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6LD41_HUMAN
    AccessioniPrimary (citable) accession number: Q6LD41
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.