Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6LD41

- Q6LD41_HUMAN

UniProt

Q6LD41 - Q6LD41_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Insulin-like growth factor-I

Gene

IGF1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. blood vessel remodeling Source: Ensembl
  2. branching morphogenesis of an epithelial tube Source: Ensembl
  3. cell development Source: Ensembl
  4. chondroitin sulfate proteoglycan biosynthetic process Source: Ensembl
  5. exocrine pancreas development Source: Ensembl
  6. extrinsic apoptotic signaling pathway in absence of ligand Source: Ensembl
  7. glial cell differentiation Source: Ensembl
  8. inner ear development Source: Ensembl
  9. insulin-like growth factor receptor signaling pathway Source: Ensembl
  10. lung alveolus development Source: Ensembl
  11. lung lobe morphogenesis Source: Ensembl
  12. lung vasculature development Source: Ensembl
  13. mammary gland development Source: Ensembl
  14. multicellular organism growth Source: Ensembl
  15. negative regulation of androgen receptor signaling pathway Source: Ensembl
  16. negative regulation of apoptotic process Source: Ensembl
  17. negative regulation of cell proliferation Source: Ensembl
  18. negative regulation of ERK1 and ERK2 cascade Source: Ensembl
  19. positive regulation of cerebellar granule cell precursor proliferation Source: Ensembl
  20. positive regulation of myoblast proliferation Source: Ensembl
  21. positive regulation of phosphatidylinositol 3-kinase signaling Source: Ensembl
  22. positive regulation of protein kinase B signaling Source: Ensembl
  23. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  24. prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis Source: Ensembl
  25. prostate gland growth Source: Ensembl
  26. prostate gland stromal morphogenesis Source: Ensembl
  27. regulation of establishment or maintenance of cell polarity Source: Ensembl
  28. regulation of protein phosphorylation Source: Ensembl
  29. Type II pneumocyte differentiation Source: Ensembl
  30. Type I pneumocyte differentiation Source: Ensembl
  31. water homeostasis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor-IImported
Gene namesi
Name:IGF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ6LD41.
ExpressionAtlasiQ6LD41. baseline and differential.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000233362.

Sequencei

Sequence statusi: Fragment.

Q6LD41 [UniParc]FASTAAdd to Basket

« Hide

        10         20
MGKISSLPTQ LFKCCFCDFL K
Length:21
Mass (Da):2,410
Last modified:July 5, 2004 - v1
Checksum:i5B299F1B0919B084
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei21 – 211Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S85346 Genomic DNA. Translation: AAB21519.1.
UniGeneiHs.160562.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S85346 Genomic DNA. Translation: AAB21519.1 .
UniGenei Hs.160562.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000233362.

Miscellaneous databases

ChiTaRSi IGF1. human.

Gene expression databases

Bgeei Q6LD41.
ExpressionAtlasi Q6LD41. baseline and differential.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Structure and function of a human insulin-like growth factor-I gene promoter."
    Kim S.W., Lajara R., Rotwein P.
    Mol. Endocrinol. 5:1964-1972(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6LD41_HUMAN
AccessioniPrimary (citable) accession number: Q6LD41
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.