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Q6LCX9

- Q6LCX9_RAT

UniProt

Q6LCX9 - Q6LCX9_RAT

Protein
Submitted name:

17 alpha-hydroxylase-17,20-desmolase

Gene

Cyp17a1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. heme binding Source: Ensembl
    2. iron ion binding Source: InterPro
    3. steroid 17-alpha-monooxygenase activity Source: Ensembl

    GO - Biological processi

    1. glucocorticoid biosynthetic process Source: Ensembl
    2. hormone biosynthetic process Source: Ensembl
    3. progesterone metabolic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    17 alpha-hydroxylase-17,20-desmolaseImported
    Gene namesi
    Name:Cyp17a1Imported
    Synonyms:CYP17Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi2456. Cyp17a1.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: Ensembl
    2. mitochondrion Source: Ensembl
    3. neuronal cell body Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriQ6LCX9.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6LCX9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    InParanoidiQ6LCX9.

    Family and domain databases

    Gene3Di1.10.630.10. 1 hit.
    InterProiIPR001128. Cyt_P450.
    [Graphical view]
    PfamiPF00067. p450. 1 hit.
    [Graphical view]
    SUPFAMiSSF48264. SSF48264. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q6LCX9-1 [UniParc]FASTAAdd to Basket

    « Hide

    VKKKIQKEID QYVGFSRTPT FNDRSHLLML EATIREVLRI RPVAPMLIPH   50
    KANVDS 56
    Length:56
    Mass (Da):6,502
    Last modified:July 5, 2004 - v1
    Checksum:iC11665548F6ACC82
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei56 – 561Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U14953 Genomic DNA. Translation: AAA85653.1.
    PIRiI56605.
    UniGeneiRn.10172.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U14953 Genomic DNA. Translation: AAA85653.1 .
    PIRi I56605.
    UniGenei Rn.10172.

    3D structure databases

    ProteinModelPortali Q6LCX9.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 2456. Cyp17a1.

    Phylogenomic databases

    InParanoidi Q6LCX9.

    Gene expression databases

    Genevestigatori Q6LCX9.

    Family and domain databases

    Gene3Di 1.10.630.10. 1 hit.
    InterProi IPR001128. Cyt_P450.
    [Graphical view ]
    Pfami PF00067. p450. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48264. SSF48264. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The rat 17 alpha-hydroxylase-17,20-desmolase (CYP17) active site: computerized homology modeling and site directed mutagenesis."
      Buczko E., Koh Y.C., Miyagawa Y., Dufau M.L.
      J. Steroid Biochem. Mol. Biol. 52:209-218(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ6LCX9_RAT
    AccessioniPrimary (citable) accession number: Q6LCX9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)