Cyp17a1

Functionⁱ

GO - Molecular functionⁱ

17-alpha-hydroxyprogesterone aldolase activity Source: InterPro
heme binding Source: InterPro
iron ion binding Source: InterPro
steroid 17-alpha-monooxygenase activity Source: InterPro

GO - Biological processⁱ

sex differentiation Source: InterPro
steroid biosynthetic process Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: 17 alpha-hydroxylase-17,20-desmolaseImported Automatic assertion inferred from database entriesⁱ EMBL:AAA85653.1
Gene namesⁱ	Name:Cyp17a1Imported Automatic assertion inferred from database entriesⁱ RGD:2456 Synonyms:CYP17Imported Automatic assertion inferred from database entriesⁱ EMBL:AAA85653.1
Organismⁱ	Rattus norvegicus (Rat)Imported Automatic assertion inferred from database entriesⁱ EMBL:AAA85653.1
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Organism-specific databases

RGDⁱ	2456. Cyp17a1.

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q6LCX9.

PaxDbⁱ

Q6LCX9.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000020035.

Bgeeⁱ

ENSRNOG00000020035.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000027160.

STRINGⁱ

10116.ENSRNOP00000027160.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6LCX9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG0156. Eukaryota. COG2124. LUCA.

eggNOGⁱ

KOG0156. Eukaryota.
COG2124. LUCA.

Family and domain databases

Gene3Dⁱ	1.10.630.10. 1 hit.
InterProⁱ	IPR033282. CYP17A1. IPR001128. Cyt_P450. [Graphical view]
PANTHERⁱ	PTHR24289:SF4. PTHR24289:SF4. 1 hit.
Pfamⁱ	PF00067. p450. 1 hit. [Graphical view]
SUPFAMⁱ	SSF48264. SSF48264. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q6LCX9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
VKKKIQKEID QYVGFSRTPT FNDRSHLLML EATIREVLRI RPVAPMLIPH 

KANVDS

Length:56

Mass (Da):6,502

Last modified:July 5, 2004 - v1

Checksum:ⁱC11665548F6ACC82

GO

Experimental Info

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Non-terminal residueⁱ	1 – 1	1	Imported Automatic assertion inferred from database entriesⁱ EMBL:AAA85653.1
Non-terminal residueⁱ	56 – 56	1	Imported Automatic assertion inferred from database entriesⁱ EMBL:AAA85653.1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U14953 Genomic DNA. Translation: AAA85653.1.
PIRⁱ	I56605.
UniGeneⁱ	Rn.10172.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U14953 Genomic DNA. Translation: AAA85653.1.
PIRⁱ	I56605.
UniGeneⁱ	Rn.10172.

3D structure databases

ProteinModelPortalⁱ	Q6LCX9.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000027160.

STRINGⁱ

10116.ENSRNOP00000027160.

Proteomic databases

PaxDbⁱ	Q6LCX9.

PaxDbⁱ

Q6LCX9.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Organism-specific databases

RGDⁱ	2456. Cyp17a1.

Phylogenomic databases

eggNOGⁱ	KOG0156. Eukaryota. COG2124. LUCA.

eggNOGⁱ

KOG0156. Eukaryota.
COG2124. LUCA.

Gene expression databases

Bgeeⁱ	ENSRNOG00000020035.

Bgeeⁱ

ENSRNOG00000020035.

Family and domain databases

Gene3Dⁱ	1.10.630.10. 1 hit.
InterProⁱ	IPR033282. CYP17A1. IPR001128. Cyt_P450. [Graphical view]
PANTHERⁱ	PTHR24289:SF4. PTHR24289:SF4. 1 hit.
Pfamⁱ	PF00067. p450. 1 hit. [Graphical view]
SUPFAMⁱ	SSF48264. SSF48264. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

Q6LCX9_RAT

Accessionⁱ

Primary (citable) accession number: Q6LCX9

Entry historyⁱ

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	September 7, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Unreviewed (UniProtKB/TrEMBL)

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - Q6LCX9 (Q6LCX9_RAT)

UniProt

Q6LCX9 - Q6LCX9_RAT

Your basket is currently empty.

17 alpha-hydroxylase-17,20-desmolase

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6LCX9 (Q6LCX9_RAT)

UniProt

Q6LCX9 - Q6LCX9_RAT

Your basket is currently empty.

17 alpha-hydroxylase-17,20-desmolase

Cyp17a1

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ