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Q6LCX9

- Q6LCX9_RAT

UniProt

Q6LCX9 - Q6LCX9_RAT

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Protein
Submitted name: 17 alpha-hydroxylase-17,20-desmolase
Gene
Cyp17a1, CYP17
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. heme binding Source: Ensembl
  2. iron ion binding Source: InterPro
  3. steroid 17-alpha-monooxygenase activity Source: Ensembl

GO - Biological processi

  1. glucocorticoid biosynthetic process Source: Ensembl
  2. hormone biosynthetic process Source: Ensembl
  3. progesterone metabolic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
17 alpha-hydroxylase-17,20-desmolaseImported
Gene namesi
Name:Cyp17a1Imported
Synonyms:CYP17Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2456. Cyp17a1.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: Ensembl
  2. mitochondrion Source: Ensembl
  3. neuronal cell body Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ6LCX9.

Structurei

3D structure databases

ProteinModelPortaliQ6LCX9.

Family & Domainsi

Phylogenomic databases

InParanoidiQ6LCX9.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
SUPFAMiSSF48264. SSF48264. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q6LCX9-1 [UniParc]FASTAAdd to Basket

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VKKKIQKEID QYVGFSRTPT FNDRSHLLML EATIREVLRI RPVAPMLIPH   50
KANVDS 56
Length:56
Mass (Da):6,502
Last modified:July 5, 2004 - v1
Checksum:iC11665548F6ACC82
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei56 – 561Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U14953 Genomic DNA. Translation: AAA85653.1.
PIRiI56605.
UniGeneiRn.10172.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U14953 Genomic DNA. Translation: AAA85653.1 .
PIRi I56605.
UniGenei Rn.10172.

3D structure databases

ProteinModelPortali Q6LCX9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 2456. Cyp17a1.

Phylogenomic databases

InParanoidi Q6LCX9.

Gene expression databases

Genevestigatori Q6LCX9.

Family and domain databases

Gene3Di 1.10.630.10. 1 hit.
InterProi IPR001128. Cyt_P450.
[Graphical view ]
Pfami PF00067. p450. 1 hit.
[Graphical view ]
SUPFAMi SSF48264. SSF48264. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The rat 17 alpha-hydroxylase-17,20-desmolase (CYP17) active site: computerized homology modeling and site directed mutagenesis."
    Buczko E., Koh Y.C., Miyagawa Y., Dufau M.L.
    J. Steroid Biochem. Mol. Biol. 52:209-218(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6LCX9_RAT
AccessioniPrimary (citable) accession number: Q6LCX9
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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