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Q6LCR5

- Q6LCR5_RAT

UniProt

Q6LCR5 - Q6LCR5_RAT

Protein

DNA-directed RNA polymerase

Gene

Polr1a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro

    Keywords - Molecular functioni

    NucleotidyltransferaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    Transcription

    Enzyme and pathway databases

    ReactomeiREACT_206206. RNA Polymerase I Transcription Initiation.
    REACT_218876. RNA Polymerase I Promoter Escape.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-directed RNA polymeraseUniRule annotation (EC:2.7.7.6UniRule annotation)
    Gene namesi
    Name:Polr1aImported
    Synonyms:Rpo1-4Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi620824. Polr1a.

    Subcellular locationi

    GO - Cellular componenti

    1. DNA-directed RNA polymerase I complex Source: Ensembl

    Keywords - Cellular componenti

    DNA-directed RNA polymeraseUniRule annotationImported

    Expressioni

    Gene expression databases

    GenevestigatoriQ6LCR5.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6LCR5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RNA polymerase beta' chain family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000205401.
    InParanoidiQ6LCR5.

    Family and domain databases

    InterProiIPR015699. DNA-dir_RNA_pol1_lsu.
    IPR007066. RNA_pol_Rpb1_3.
    [Graphical view]
    PANTHERiPTHR19376:SF11. PTHR19376:SF11. 1 hit.
    PfamiPF04983. RNA_pol_Rpb1_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q6LCR5-1 [UniParc]FASTAAdd to Basket

    « Hide

    AHFPQSELGR AEAYVLACTD QQYLVPKDGQ PLAGLIQDHM VSGANMTIRG   50
    CFFTREQYME LVYRGLTDKV GRVKLFPPAI LKPFPL 86
    Length:86
    Mass (Da):9,655
    Last modified:July 5, 2004 - v1
    Checksum:i1FBC864CE073E33B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei86 – 861Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33459 mRNA. Translation: AAC99958.1.
    UniGeneiRn.24877.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33459 mRNA. Translation: AAC99958.1 .
    UniGenei Rn.24877.

    3D structure databases

    ProteinModelPortali Q6LCR5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    RGDi 620824. Polr1a.

    Phylogenomic databases

    HOGENOMi HOG000205401.
    InParanoidi Q6LCR5.

    Enzyme and pathway databases

    Reactomei REACT_206206. RNA Polymerase I Transcription Initiation.
    REACT_218876. RNA Polymerase I Promoter Escape.

    Gene expression databases

    Genevestigatori Q6LCR5.

    Family and domain databases

    InterProi IPR015699. DNA-dir_RNA_pol1_lsu.
    IPR007066. RNA_pol_Rpb1_3.
    [Graphical view ]
    PANTHERi PTHR19376:SF11. PTHR19376:SF11. 1 hit.
    Pfami PF04983. RNA_pol_Rpb1_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Wang D., Stetler D.A.
      Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LiverImported.

    Entry informationi

    Entry nameiQ6LCR5_RAT
    AccessioniPrimary (citable) accession number: Q6LCR5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)