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Q6LCR5

- Q6LCR5_RAT

UniProt

Q6LCR5 - Q6LCR5_RAT

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Protein

DNA-directed RNA polymerase

Gene

Polr1a

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. DNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseUniRule annotationImported, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

ReactomeiREACT_206206. RNA Polymerase I Transcription Initiation.
REACT_218876. RNA Polymerase I Promoter Escape.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymeraseUniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:Polr1aImported
Synonyms:Rpo1-4Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620824. Polr1a.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. DNA-directed RNA polymerase I complex Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

DNA-directed RNA polymeraseUniRule annotationImported

Expressioni

Gene expression databases

ExpressionAtlasiQ6LCR5. baseline and differential.
GenevestigatoriQ6LCR5.

Structurei

3D structure databases

ProteinModelPortaliQ6LCR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000205401.

Family and domain databases

InterProiIPR015699. DNA-dir_RNA_pol1_lsu.
IPR007066. RNA_pol_Rpb1_3.
[Graphical view]
PANTHERiPTHR19376:SF11. PTHR19376:SF11. 1 hit.
PfamiPF04983. RNA_pol_Rpb1_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q6LCR5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
AHFPQSELGR AEAYVLACTD QQYLVPKDGQ PLAGLIQDHM VSGANMTIRG
60 70 80
CFFTREQYME LVYRGLTDKV GRVKLFPPAI LKPFPL
Length:86
Mass (Da):9,655
Last modified:July 5, 2004 - v1
Checksum:i1FBC864CE073E33B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei86 – 861Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U33459 mRNA. Translation: AAC99958.1.
UniGeneiRn.24877.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U33459 mRNA. Translation: AAC99958.1 .
UniGenei Rn.24877.

3D structure databases

ProteinModelPortali Q6LCR5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 620824. Polr1a.

Phylogenomic databases

HOGENOMi HOG000205401.

Enzyme and pathway databases

Reactomei REACT_206206. RNA Polymerase I Transcription Initiation.
REACT_218876. RNA Polymerase I Promoter Escape.

Gene expression databases

ExpressionAtlasi Q6LCR5. baseline and differential.
Genevestigatori Q6LCR5.

Family and domain databases

InterProi IPR015699. DNA-dir_RNA_pol1_lsu.
IPR007066. RNA_pol_Rpb1_3.
[Graphical view ]
PANTHERi PTHR19376:SF11. PTHR19376:SF11. 1 hit.
Pfami PF04983. RNA_pol_Rpb1_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Wang D., Stetler D.A.
    Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LiverImported.

Entry informationi

Entry nameiQ6LCR5_RAT
AccessioniPrimary (citable) accession number: Q6LCR5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)