Unreviewed, UniProtKB/TrEMBL Q6LC83 (Q6LC83_HUMAN)

Names and origin

Protein names

Submitted name:
    Cyclin dependent protein kinase EMBL AAB50213.1
Submitted name:
    Cyclin-dependent kinase 4, isoform CRA_b EMBL EAW97059.1

Gene names

Name:	CDK4 EMBL EAW97059.1
ORF Names:	hCG_40151 EMBL EAW97059.1

Organism

Homo sapiens (Human) EMBL AAB50213.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Cyclin EMBL AAB50213.1 Kinase EMBL AAB50213.1 Transferase
Gene Ontology (GO)
Biological process	protein amino acid phosphorylation Inferred from electronic annotation. Source: InterPro regulation of cell cycle Inferred from electronic annotation. Source: Compara regulation of cell proliferation Inferred from electronic annotation. Source: Compara signal transduction Inferred from electronic annotation. Source: Compara
Cellular component	cyclin-dependent protein kinase holoenzyme complex Inferred from electronic annotation. Source: Compara transcription factor complex Inferred from electronic annotation. Source: Compara
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro cyclin-dependent protein kinase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6LC83-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F02FB3349583BEDF	FASTA	229	25,906
	10 20 30 40 50 60 MDVCATSRTD REIKVTLVFE HVDQDLRTYL DKAPPPGLPA ETIKDLMRQF LRGLDFLHAN 70 80 90 100 110 120 CIVHRDLKPE NILVTSGGTV KLADFGLARI YSYQMALTPV VVTLWYRAPE VLLQSTYATP 130 140 150 160 170 180 VDMWSVGCIF AEMFRRKPLF CGNSEADQLG KIFDLIGLPP EDDWPRDVSL PRGAFPPRGP 190 200 210 220 RPVQSVVPEM EESGAQLLLE MLTFNPHKRI SAFRALQHSY LHKDEGNPE

References

[1]	"A "double adaptor" method for improved shotgun library construction." Andersson B., Wentland M.A., Ricafrente J.Y., Liu W., Gibbs R.A. Anal. Biochem. 236:107-113(1996) [PubMed: 8619474] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL AAB50213.1.
[2]	"Large-scale concatenation cDNA sequencing." Yu W., Andersson B., Worley K.C., Muzny D.M., Ding Y., Liu W., Ricafrente J.Y., Wentland M.A., Lennon G., Gibbs R.A. Genome Res. 7:353-358(1997) [PubMed: 9110174] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL AAB50213.1.
[3]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U79269 mRNA. Translation: AAB50213.1. CH471054 Genomic DNA. Translation: EAW97059.1.
IPI	IPI00007811.
UniGene	Hs.95577
3D structure databases
HSSP	HSSP built from PDB template 1KE8 based on UniProtKB P24941.
SMR	Q6LC83. Positions 2-225.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6LC83.
Genome annotation databases
Ensembl	ENST00000257904; ENSP00000257904; ENSG00000135446; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:1773. CDK4.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q6LC83.
Gene expression databases
ArrayExpress	Q6LC83.
Bgee	Q6LC83.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017442. Se/Thr_prot_kinase-like_dom. IPR008271. Ser/Thr_prot_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6LC83_HUMAN

Accession

Primary (citable) accession number: Q6LC83

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 19, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.