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Protein
Submitted name:

Cyclin dependent protein kinase

Gene

CDK4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

CyclinImported, KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin dependent protein kinaseImported
Submitted name:
Cyclin-dependent kinase 4, isoform CRA_bImported
Gene namesi
Name:CDK4Imported
ORF Names:hCG_40151Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiQ6LC83.

Expressioni

Gene expression databases

BgeeiENSG00000135446.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000257904.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 221221Protein kinaseInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0594. Eukaryota.
ENOG410XPP3. LUCA.
HOVERGENiHBG014652.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6LC83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVCATSRTD REIKVTLVFE HVDQDLRTYL DKAPPPGLPA ETIKDLMRQF
60 70 80 90 100
LRGLDFLHAN CIVHRDLKPE NILVTSGGTV KLADFGLARI YSYQMALTPV
110 120 130 140 150
VVTLWYRAPE VLLQSTYATP VDMWSVGCIF AEMFRRKPLF CGNSEADQLG
160 170 180 190 200
KIFDLIGLPP EDDWPRDVSL PRGAFPPRGP RPVQSVVPEM EESGAQLLLE
210 220
MLTFNPHKRI SAFRALQHSY LHKDEGNPE
Length:229
Mass (Da):25,906
Last modified:July 5, 2004 - v1
Checksum:iF02FB3349583BEDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U79269 mRNA. Translation: AAB50213.1.
CH471054 Genomic DNA. Translation: EAW97059.1.
UniGeneiHs.95577.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U79269 mRNA. Translation: AAB50213.1.
CH471054 Genomic DNA. Translation: EAW97059.1.
UniGeneiHs.95577.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000257904.

Proteomic databases

PeptideAtlasiQ6LC83.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0594. Eukaryota.
ENOG410XPP3. LUCA.
HOVERGENiHBG014652.

Miscellaneous databases

ChiTaRSiCDK4. human.

Gene expression databases

BgeeiENSG00000135446.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6LC83_HUMAN
AccessioniPrimary (citable) accession number: Q6LC83
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.