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Protein
Submitted name:

Transforming growth factor-alpha

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

  1. activation of MAPK activity Source: Ensembl
  2. negative regulation of apoptotic process Source: Ensembl
  3. positive regulation of epidermal growth factor-activated receptor activity Source: Ensembl
  4. positive regulation of epithelial cell proliferation Source: Ensembl
  5. positive regulation of mitotic nuclear division Source: Ensembl
  6. response to drug Source: Ensembl
  7. wound healing Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming growth factor-alphaImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. basolateral plasma membrane Source: Ensembl
  2. cell surface Source: Ensembl
  3. cytoplasmic vesicle Source: Ensembl
  4. extracellular space Source: Ensembl
  5. nucleus Source: Ensembl
  6. perinuclear region of cytoplasm Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ6LC37.
ExpressionAtlasiQ6LC37. baseline and differential.
GenevestigatoriQ6LC37.

Sequencei

Sequence statusi: Fragment.

Q6LC37-1 [UniParc]FASTAAdd to basket

« Hide

        10 
HEKPSALLKG RTACCHSET
Length:19
Mass (Da):2,068
Last modified:July 5, 2004 - v1
Checksum:iE37CC4FF4C92FE5B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei19 – 191Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89794 Genomic DNA. Translation: AAC53174.1.
UniGeneiMm.137222.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89794 Genomic DNA. Translation: AAC53174.1.
UniGeneiMm.137222.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiQ6LC37.
ExpressionAtlasiQ6LC37. baseline and differential.
GenevestigatoriQ6LC37.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Integration of HTLV-1 provirus into mouse transforming growth factor-alpha gene."
    Fang J., Kushida S., Feng R., Tanaka M., Kikukawa H., Kawamura T., Uchida K., Miwa M.
    Biochem. Biophys. Res. Commun. 233:792-795(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C3H/HeJImported.

Entry informationi

Entry nameiQ6LC37_MOUSE
AccessioniPrimary (citable) accession number: Q6LC37
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 1, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.