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Q6LBZ1 (Q6LBZ1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismHomo sapiens (Human) EMBL CAA25017.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length176 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Secreted By similarity SAAS SAAS000074.

Ontologies

Keywords
   Biological processLipid transport SAAS SAAS000074
Transport
   Cellular componentSecreted SAAS SAAS000074
   PTMLipoprotein EMBL CAA25017.1
Gene Ontology (GO)
   Biological_processaging

Inferred from electronic annotation. Source: Ensembl

artery morphogenesis

Inferred from electronic annotation. Source: Ensembl

cellular calcium ion homeostasis

Inferred from electronic annotation. Source: Ensembl

cellular response to cholesterol

Inferred from electronic annotation. Source: Ensembl

cellular response to growth factor stimulus

Inferred from electronic annotation. Source: Ensembl

cellular response to interleukin-1

Inferred from electronic annotation. Source: Ensembl

cholesterol catabolic process

Inferred from electronic annotation. Source: Ensembl

cholesterol efflux

Inferred from electronic annotation. Source: Ensembl

cholesterol homeostasis

Inferred from electronic annotation. Source: Ensembl

lipoprotein biosynthetic process

Inferred from electronic annotation. Source: Ensembl

lipoprotein catabolic process

Inferred from electronic annotation. Source: Ensembl

low-density lipoprotein particle remodeling

Inferred from electronic annotation. Source: Ensembl

maintenance of location in cell

Inferred from electronic annotation. Source: Ensembl

negative regulation of inflammatory response

Inferred from electronic annotation. Source: Ensembl

negative regulation of neuron apoptotic process

Inferred from electronic annotation. Source: Ensembl

oligodendrocyte differentiation

Inferred from electronic annotation. Source: Ensembl

peripheral nervous system axon regeneration

Inferred from electronic annotation. Source: Ensembl

positive regulation of axon extension

Inferred from electronic annotation. Source: Ensembl

positive regulation of cholesterol esterification

Inferred from electronic annotation. Source: Ensembl

regulation of gene expression

Inferred from electronic annotation. Source: Ensembl

response to dietary excess

Inferred from electronic annotation. Source: Ensembl

response to ethanol

Inferred from electronic annotation. Source: Ensembl

response to insulin

Inferred from electronic annotation. Source: Ensembl

response to oxidative stress

Inferred from electronic annotation. Source: Ensembl

response to retinoic acid

Inferred from electronic annotation. Source: Ensembl

vasodilation

Inferred from electronic annotation. Source: Ensembl

very-low-density lipoprotein particle remodeling

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentGolgi apparatus

Inferred from electronic annotation. Source: Ensembl

dendrite

Inferred from electronic annotation. Source: Ensembl

extrinsic component of external side of plasma membrane

Inferred from electronic annotation. Source: Ensembl

late endosome

Inferred from electronic annotation. Source: Ensembl

low-density lipoprotein particle

Inferred from electronic annotation. Source: Ensembl

neuronal cell body

Inferred from electronic annotation. Source: Ensembl

   Molecular_functioncholesterol transporter activity

Inferred from electronic annotation. Source: Ensembl

hydroxyapatite binding

Inferred from electronic annotation. Source: Ensembl

lipoprotein particle binding

Inferred from electronic annotation. Source: Ensembl

phosphatidylcholine-sterol O-acyltransferase activator activity

Inferred from electronic annotation. Source: Ensembl

phospholipid binding

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL CAA25017.1
Non-terminal residue1761 EMBL CAA25017.1

Sequences

Sequence LengthMass (Da)Tools
Q6LBZ1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: FD7312DD136F055E

FASTA17619,910
        10         20         30         40         50         60 
QVQEELLSSQ VTQELRALMD ETMKELKAYK SELEEQLTPV AEETRARLSK ELQAAQARLG 

        70         80         90        100        110        120 
ADMEDVCGRL VQYRGEVQAM LGQSTEELRV RLASHLRKLR KRLLRDADDL QKRLAVYQAG 

       130        140        150        160        170 
AREGAERGLS AIRERLGPLV EQGRVRAATV GSLAGQPLQE RAQAWGERLR ARMEEM 

« Hide

References

[1]"The isolation of cDNA clones for human apolipoprotein E and the detection of apoE RNA in hepatic and extra-hepatic tissues."
Wallis S.C., Rogne S., Gill L., Markham A., Edge M., Woods D., Williamson R., Humphries S.
EMBO J. 2:2369-2373(1983) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X00199 mRNA. Translation: CAA25017.1.
UniGeneHs.654439.

3D structure databases

ProteinModelPortalQ6LBZ1.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ6LBZ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOGENOMHOG000034006.
HOVERGENHBG010582.

Gene expression databases

ArrayExpressQ6LBZ1.
BgeeQ6LBZ1.

Family and domain databases

InterProIPR000074. ApoA1_A4_E.
[Graphical view]
PfamPF01442. Apolipoprotein. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6LBZ1_HUMAN
AccessionPrimary (citable) accession number: Q6LBZ1
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.