Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6L6Q6

- LYS_CRAGI

UniProt

Q6L6Q6 - LYS_CRAGI

Protein

Lysozyme

Gene

lysoz

Organism
Crassostrea gigas (Pacific oyster) (Crassostrea angulata)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    May play a role in digestion and in the host defense mechanisms against invading microbes.

    Catalytic activityi

    Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

    GO - Molecular functioni

    1. lysozyme activity Source: UniProtKB-EC

    GO - Biological processi

    1. cytolysis Source: UniProtKB-KW
    2. defense response to bacterium Source: UniProtKB-KW

    Keywords - Molecular functioni

    Antibiotic, Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

    Protein family/group databases

    CAZyiGH22. Glycoside Hydrolase Family 22.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lysozyme (EC:3.2.1.17)
    Alternative name(s):
    1,4-beta-N-acetylmuramidase
    Gene namesi
    Name:lysoz
    OrganismiCrassostrea gigas (Pacific oyster) (Crassostrea angulata)
    Taxonomic identifieri29159 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaOstreoidaOstreoideaOstreidaeCrassostrea

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 137117LysozymePRO_0000280511Add
    BLAST

    Expressioni

    Tissue specificityi

    Expressed in the basophil cells of the oyster digestive gland.1 Publication

    Structurei

    3D structure databases

    ProteinModelPortaliQ6L6Q6.
    SMRiQ6L6Q6. Positions 17-130.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the lysozyme type I family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    InterProiIPR008597. Destabilase.
    IPR023346. Lysozyme-like_dom.
    [Graphical view]
    PANTHERiPTHR11195. PTHR11195. 1 hit.
    PfamiPF05497. Destabilase. 1 hit.
    [Graphical view]
    SUPFAMiSSF53955. SSF53955. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6L6Q6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQRLLGSIVI LATVFTFCEA TISSACLRCI CNVESGCRPI GCHYDVYSYS    50
    CGYFQIKENY WEDCGKPGTS FKACANDYTC ASNCVRAYMK RYIGSSGCPA 100
    NCESYARIHN GGPRGCRHPS TLRYWEKVHQ QGCNVNS 137
    Length:137
    Mass (Da):15,274
    Last modified:July 5, 2004 - v1
    Checksum:i1E2A8F1AF5403CE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB179775 mRNA. Translation: BAD19059.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB179775 mRNA. Translation: BAD19059.1 .

    3D structure databases

    ProteinModelPortali Q6L6Q6.
    SMRi Q6L6Q6. Positions 17-130.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH22. Glycoside Hydrolase Family 22.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR008597. Destabilase.
    IPR023346. Lysozyme-like_dom.
    [Graphical view ]
    PANTHERi PTHR11195. PTHR11195. 1 hit.
    Pfami PF05497. Destabilase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53955. SSF53955. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of cDNAs and hybridization analysis of lysozymes from two oyster species, Crassostrea gigas and Ostrea edulis."
      Matsumoto T., Nakamura A.M., Takahashi K.G.
      Comp. Biochem. Physiol. 145B:325-330(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiLYS_CRAGI
    AccessioniPrimary (citable) accession number: Q6L6Q6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 20, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3