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Protein
Submitted name:

FML2_HUMAN

Gene

FPRL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
FML2_HUMANImported
Submitted name:
Formyl peptide receptor-like 2Imported
Submitted name:
cDNA FLJ77388, highly similar to Homo sapiens formyl peptide receptor-like 2 (FPRL2), mRNAImported
Gene namesi
Name:FPRL2Imported
ORF Names:hCG_91958Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000187474.4

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 50HelicalSequence analysisAdd BLAST27
Transmembranei62 – 80HelicalSequence analysisAdd BLAST19
Transmembranei100 – 121HelicalSequence analysisAdd BLAST22
Transmembranei141 – 164HelicalSequence analysisAdd BLAST24
Transmembranei200 – 221HelicalSequence analysisAdd BLAST22
Transmembranei242 – 267HelicalSequence analysisAdd BLAST26
Transmembranei279 – 305HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162388910

Chemistry databases

ChEMBLiCHEMBL5646

Expressioni

Gene expression databases

BgeeiENSG00000187474
ExpressionAtlasiQ6L5J4 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ6L5J4, 1 interactor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 302G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST260

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IGAX Eukaryota
ENOG410XQ5U LUCA
HOVERGENiHBG107927
KOiK04173
OMAiVAMREKW
OrthoDBiEOG091G09ZK

Family and domain databases

InterProiView protein in InterPro
IPR027347 Formyl_pep_2/3_rcpt
IPR000826 Formyl_rcpt-rel
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PANTHERiPTHR24225 PTHR24225, 1 hit
PTHR24225:SF16 PTHR24225:SF16, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6L5J4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METNFSIPLN ETEEVLPEPA GHTVLWIFSL LVHGVTFVFG VLGNGLVIWV
60 70 80 90 100
AGFRMTRTVN TICYLNLALA DFSFSAILPF RMVSVAMREK WPFGSFLCKL
110 120 130 140 150
VHVMIDINLF VSVYLITIIA LDRCICVLHP AWAQNHRTMS LAKRVMTGLW
160 170 180 190 200
IFTIVLTLPN FIFWTTISTT NGDTYCIFNF AFWGDTAVER LNVFITMAKV
210 220 230 240 250
FLILHFIIGF SVPMSIITVC YGIIAAKIHR NHMIKSSRPL RVFAAVVASF
260 270 280 290 300
FICWFPYELI GILMAVWLKE MLLNGKYKII LVLINPTSSL AFFNSCLNPI
310 320 330 340 350
LYVFMGRNFQ ERLIRSLPTS LERALTEVPD SAQTSNTDTT SASPPEETEL

QAM
Length:353
Mass (Da):39,965
Last modified:May 10, 2005 - v1
Checksum:iFFB7150B6A833F4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005946 Genomic DNA Translation: AAC72102.1
AK292541 mRNA Translation: BAF85230.1
CH471135 Genomic DNA Translation: EAW72045.1
RefSeqiNP_002021.3, NM_002030.4
XP_011524989.1, XM_011526687.2
UniGeneiHs.445466

Genome annotation databases

GeneIDi2359
KEGGihsa:2359
UCSCiuc002pxt.2 human

Similar proteinsi

Entry informationi

Entry nameiQ6L5J4_HUMAN
AccessioniPrimary (citable) accession number: Q6L5J4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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