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Protein
Submitted name:

FML2_HUMAN

Gene

FPRL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
FML2_HUMANImported
Submitted name:
Formyl peptide receptor-like 2Imported
Submitted name:
cDNA FLJ77388, highly similar to Homo sapiens formyl peptide receptor-like 2 (FPRL2), mRNAImported
Gene namesi
Name:FPRL2Imported
ORF Names:hCG_91958Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162388910.

PTM / Processingi

Proteomic databases

PRIDEiQ6L5J4.

Expressioni

Gene expression databases

BgeeiQ6L5J4.
ExpressionAtlasiQ6L5J4. baseline and differential.
GenevisibleiQ6L5J4. HS.

Interactioni

Protein-protein interaction databases

IntActiQ6L5J4. 1 interaction.
STRINGi9606.ENSP00000341821.

Structurei

3D structure databases

ProteinModelPortaliQ6L5J4.
SMRiQ6L5J4. Positions 4-344.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOVERGENiHBG107927.
KOiK04173.
OMAiVAMREKW.
PhylomeDBiQ6L5J4.

Family and domain databases

InterProiIPR027347. Formyl_pep_2/3_rcpt.
IPR000826. Formyl_rcpt-rel.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24225. PTHR24225. 1 hit.
PTHR24225:SF16. PTHR24225:SF16. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6L5J4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METNFSIPLN ETEEVLPEPA GHTVLWIFSL LVHGVTFVFG VLGNGLVIWV
60 70 80 90 100
AGFRMTRTVN TICYLNLALA DFSFSAILPF RMVSVAMREK WPFGSFLCKL
110 120 130 140 150
VHVMIDINLF VSVYLITIIA LDRCICVLHP AWAQNHRTMS LAKRVMTGLW
160 170 180 190 200
IFTIVLTLPN FIFWTTISTT NGDTYCIFNF AFWGDTAVER LNVFITMAKV
210 220 230 240 250
FLILHFIIGF SVPMSIITVC YGIIAAKIHR NHMIKSSRPL RVFAAVVASF
260 270 280 290 300
FICWFPYELI GILMAVWLKE MLLNGKYKII LVLINPTSSL AFFNSCLNPI
310 320 330 340 350
LYVFMGRNFQ ERLIRSLPTS LERALTEVPD SAQTSNTDTT SASPPEETEL

QAM
Length:353
Mass (Da):39,965
Last modified:May 10, 2005 - v1
Checksum:iFFB7150B6A833F4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005946 Genomic DNA. Translation: AAC72102.1.
AK292541 mRNA. Translation: BAF85230.1.
CH471135 Genomic DNA. Translation: EAW72045.1.
RefSeqiNP_002021.3. NM_002030.3.
XP_011524989.1. XM_011526687.1.
UniGeneiHs.445466.

Genome annotation databases

GeneIDi2359.
KEGGihsa:2359.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005946 Genomic DNA. Translation: AAC72102.1.
AK292541 mRNA. Translation: BAF85230.1.
CH471135 Genomic DNA. Translation: EAW72045.1.
RefSeqiNP_002021.3. NM_002030.3.
XP_011524989.1. XM_011526687.1.
UniGeneiHs.445466.

3D structure databases

ProteinModelPortaliQ6L5J4.
SMRiQ6L5J4. Positions 4-344.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6L5J4. 1 interaction.
STRINGi9606.ENSP00000341821.

Chemistry

BindingDBiQ6L5J4.
ChEMBLiCHEMBL5646.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PRIDEiQ6L5J4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2359.
KEGGihsa:2359.

Organism-specific databases

CTDi2359.
PharmGKBiPA162388910.

Phylogenomic databases

HOVERGENiHBG107927.
KOiK04173.
OMAiVAMREKW.
PhylomeDBiQ6L5J4.

Miscellaneous databases

GenomeRNAii2359.
NextBioi9571.

Gene expression databases

BgeeiQ6L5J4.
ExpressionAtlasiQ6L5J4. baseline and differential.
GenevisibleiQ6L5J4. HS.

Family and domain databases

InterProiIPR027347. Formyl_pep_2/3_rcpt.
IPR000826. Formyl_rcpt-rel.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24225. PTHR24225. 1 hit.
PTHR24225:SF16. PTHR24225:SF16. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
  2. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ6L5J4_HUMAN
AccessioniPrimary (citable) accession number: Q6L5J4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: July 22, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.