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Q6L5F7

- MPK17_ORYSJ

UniProt

Q6L5F7 - MPK17_ORYSJ

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Protein

Mitogen-activated protein kinase 17

Gene

MPK17

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulationi

Activated by threonine and tyrosine phosphorylation.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei134 – 1341ATPPROSITE-ProRule annotation
Active sitei231 – 2311Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi111 – 1199ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinase 17 (EC:2.7.11.24)
Short name:
MAP kinase 17
Gene namesi
Name:MPK17
Ordered Locus Names:Os05g0576800, LOC_Os05g50120
ORF Names:OJ1126_B10.5
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 5

Organism-specific databases

GrameneiQ6L5F7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 582582Mitogen-activated protein kinase 17PRO_0000239760Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei267 – 2671PhosphothreonineBy similarity
Modified residuei269 – 2691PhosphotyrosineBy similarity

Post-translational modificationi

Dually phosphorylated on Thr-267 and Tyr-269, which activates the enzyme.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ6L5F7.

Expressioni

Inductioni

By ethylene and infection with rice blast fungus (M.grisea).1 Publication

Gene expression databases

ExpressionAtlasiQ6L5F7. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ6L5F7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini105 – 396292Protein kinasePROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi267 – 2693TXY

Domaini

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
InParanoidiQ6L5F7.
OMAiDHISDAT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6L5F7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGGRARSILR WLRHHRSRRV SSSSFHLTTT GDDTVKDLHD PRREDAEGDG
60 70 80 90 100
WEEVHEGPES DPEEYIALVS EDAGTHLPVR TEPRRMDPSK KEPDFFTEYG
110 120 130 140 150
EANRYKVSEV IGKGSYGVVA AAVDTQTGER VAIKKINDVF DHVSDATRIL
160 170 180 190 200
REIKLLRLLR HPDIVEIKHI MLPPSRREFR DIYVIFELME SDLHQVIKAN
210 220 230 240 250
DDLTPEHHQF FLYQLLRGMK YIHAASVFHR DLKPKNILAN ADCKLKVCDF
260 270 280 290 300
GLARVSFNDT PSAIFWTDYV ATRWYRAPEL CGSFFSKYTP AIDIWSVGCI
310 320 330 340 350
FAELLTGKPL FPGKNVVHQL DLMTDLLGTP SAESLAKIRN EKARRYLSNM
360 370 380 390 400
RKKPRVPFTK KFPGVDPMAL HLLERLLAFD PKDRPSAEEA LTDPYFNGLA
410 420 430 440 450
NSEREPIAQP ISKLEFEFEK RKLAKDDVRE LIYREILEYH PHMLQEYLRG
460 470 480 490 500
GDQMSFMYPS GVDRFKRQFA HLEEGVSKGE KSSPQLRQNA SLPRERAIGN
510 520 530 540 550
KHGDDEYHAK LNVGEKPCHA SVTDGISKPL MSARSLLKSE SISASKCIGE
560 570 580
KPKQDRDQED SLTESMDETA DEVSEKVAQL KT
Length:582
Mass (Da):66,487
Last modified:June 13, 2006 - v2
Checksum:i78DCBD1DEB835292
GO

Sequence cautioni

The sequence AAT39148.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC098571 Genomic DNA. Translation: AAT39148.1. Sequence problems.
AK070644 mRNA. No translation available.
RefSeqiNP_001056404.1. NM_001062939.1.
UniGeneiOs.34647.

Genome annotation databases

EnsemblPlantsiOS05T0576800-01; OS05T0576800-01; OS05G0576800.
GeneIDi4339697.
KEGGiosa:4339697.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC098571 Genomic DNA. Translation: AAT39148.1 . Sequence problems.
AK070644 mRNA. No translation available.
RefSeqi NP_001056404.1. NM_001062939.1.
UniGenei Os.34647.

3D structure databases

ProteinModelPortali Q6L5F7.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q6L5F7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS05T0576800-01 ; OS05T0576800-01 ; OS05G0576800 .
GeneIDi 4339697.
KEGGi osa:4339697.

Organism-specific databases

Gramenei Q6L5F7.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
InParanoidi Q6L5F7.
OMAi DHISDAT.

Gene expression databases

ExpressionAtlasi Q6L5F7. baseline.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  3. "Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
    Reyna N.S., Yang Y.
    Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INDUCTION, NOMENCLATURE.

Entry informationi

Entry nameiMPK17_ORYSJ
AccessioniPrimary (citable) accession number: Q6L5F7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: June 13, 2006
Last modified: October 29, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3