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Q6L5F7 (MPK17_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitogen-activated protein kinase 17

Short name=MAP kinase 17
EC=2.7.11.24
Gene names
Name:MPK17
Ordered Locus Names:Os05g0576800, LOC_Os05g50120
ORF Names:OJ1126_B10.5
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length582 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation

Activated by threonine and tyrosine phosphorylation By similarity.

Induction

By ethylene and infection with rice blast fungus (M.grisea). Ref.3

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Post-translational modification

Dually phosphorylated on Thr-267 and Tyr-269, which activates the enzyme By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Contains 1 protein kinase domain.

Sequence caution

The sequence AAT39148.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 582582Mitogen-activated protein kinase 17
PRO_0000239760

Regions

Domain105 – 396292Protein kinase
Nucleotide binding111 – 1199ATP By similarity
Motif267 – 2693TXY

Sites

Active site2311Proton acceptor By similarity
Binding site1341ATP By similarity

Amino acid modifications

Modified residue2671Phosphothreonine By similarity
Modified residue2691Phosphotyrosine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6L5F7 [UniParc].

Last modified June 13, 2006. Version 2.
Checksum: 78DCBD1DEB835292

FASTA58266,487
        10         20         30         40         50         60 
MGGRARSILR WLRHHRSRRV SSSSFHLTTT GDDTVKDLHD PRREDAEGDG WEEVHEGPES 

        70         80         90        100        110        120 
DPEEYIALVS EDAGTHLPVR TEPRRMDPSK KEPDFFTEYG EANRYKVSEV IGKGSYGVVA 

       130        140        150        160        170        180 
AAVDTQTGER VAIKKINDVF DHVSDATRIL REIKLLRLLR HPDIVEIKHI MLPPSRREFR 

       190        200        210        220        230        240 
DIYVIFELME SDLHQVIKAN DDLTPEHHQF FLYQLLRGMK YIHAASVFHR DLKPKNILAN 

       250        260        270        280        290        300 
ADCKLKVCDF GLARVSFNDT PSAIFWTDYV ATRWYRAPEL CGSFFSKYTP AIDIWSVGCI 

       310        320        330        340        350        360 
FAELLTGKPL FPGKNVVHQL DLMTDLLGTP SAESLAKIRN EKARRYLSNM RKKPRVPFTK 

       370        380        390        400        410        420 
KFPGVDPMAL HLLERLLAFD PKDRPSAEEA LTDPYFNGLA NSEREPIAQP ISKLEFEFEK 

       430        440        450        460        470        480 
RKLAKDDVRE LIYREILEYH PHMLQEYLRG GDQMSFMYPS GVDRFKRQFA HLEEGVSKGE 

       490        500        510        520        530        540 
KSSPQLRQNA SLPRERAIGN KHGDDEYHAK LNVGEKPCHA SVTDGISKPL MSARSLLKSE 

       550        560        570        580 
SISASKCIGE KPKQDRDQED SLTESMDETA DEVSEKVAQL KT 

« Hide

References

« Hide 'large scale' references
[1]"A fine physical map of the rice chromosome 5."
Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.
Mol. Genet. Genomics 274:337-345(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[3]"Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
Reyna N.S., Yang Y.
Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC098571 Genomic DNA. Translation: AAT39148.1. Sequence problems.
AK070644 mRNA. No translation available.
RefSeqNP_001056404.1. NM_001062939.1.
UniGeneOs.34647.

3D structure databases

ProteinModelPortalQ6L5F7.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ6L5F7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsOS05T0576800-01; OS05T0576800-01; OS05G0576800.
GeneID4339697.
KEGGosa:4339697.

Organism-specific databases

GrameneQ6L5F7.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000233024.
OMADHISDAT.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPK17_ORYSJ
AccessionPrimary (citable) accession number: Q6L5F7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: June 13, 2006
Last modified: May 14, 2014
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations