Q6L5C4 (P2C52_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 52
Short name=OsPP2C52
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os05g0587100, LOC_Os05g50970
ORF Names:	OJ1007_H05.6, OsJ_000225

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	491 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 491	491	Probable protein phosphatase 2C 52		PRO_0000363299
Regions
	Domain	228 – 468	241	PP2C-like
	Compositional bias	14 – 51	38	Ala-rich
	Compositional bias	94 – 213	120	Glu-rich
Sites
	Metal binding	265	1	Manganese 1 By similarity
	Metal binding	265	1	Manganese 2 By similarity
	Metal binding	266	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	427	1	Manganese 2 By similarity
	Metal binding	466	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6L5C4 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 5FBEA073B5D07327	FASTA	491	52,919
	10 20 30 40 50 60 MVYDGAVKDQ ESSANPASAS AALSEASAAA SEVTAAAAAG AGAGAAEEGA AVSGRPPRPP 70 80 90 100 110 120 HDKRLGVRHP LKHRRFRAGG KVMVEPGDPP SAQEVADEEA SEVEQEAAPV EREPPQEEGG 130 140 150 160 170 180 DVEVSSAPAE MEVVEGDAME VSPEPAVAVG ESELEGRPGE EEEVSSPVVS QGERKQETAA 190 200 210 220 230 240 AAPVPAVEEK KHKDQENKHK EREREKERER VDEVGYMSGG WKSEDGFLSC GYSSFRGKRA 250 260 270 280 290 300 SMEDFYDIKS SKIDDKQISL FGIFDGHGGS RAAEYLKEHL FENLMKHPEF MTNTKLAISE 310 320 330 340 350 360 TYKKTDSEFL DSESHTHRDD GSTASTAVLV GNHLYVANVG DSRAVISKAG KAIALSEDHK 370 380 390 400 410 420 PNRSDERKRI ESAGGVVMWA GTWRVGGVLA MSRAFGNRLL KQFVVADPEI QEQEIDDELE 430 440 450 460 470 480 FLILASDGLW DVVPNEDAVS LVKIEEEPEA AARKLTETAF SRGSGDNITC IVVKFQHDKM 490 DGDSSPTSDK S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A fine physical map of the rice chromosome 5." Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y. Mol. Genet. Genomics 274:337-345(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[5]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[6]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC098598 Genomic DNA. Translation: AAT44157.1. AP008211 Genomic DNA. Translation: BAF18381.1. CM000138 Genomic DNA. Translation: EAZ10400.1. AK101645 mRNA. Translation: BAG95168.1.
RefSeq	NP_001056467.1. NM_001063002.1.
UniGene	Os.5928.
3D structure databases
HSSP	HSSP built from PDB template 1A6Q based on UniProtKB P35813.
ProteinModelPortal	Q6L5C4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os05g50970.1; LOC_Os05g50970.1; LOC_Os05g50970.
GeneID	4339763.
KEGG	osa:4339763.
Organism-specific databases
Gramene	Q6L5C4.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
OMA	THRDDGS.
ProtClustDB	CLSN2695853.
Gene expression databases
ArrayExpress	Q6L5C4.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C52_ORYSJ

Accession

Primary (citable) accession number: Q6L5C4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	July 5, 2004
Last modified:	April 3, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program