Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Gibberellin receptor GID1

Gene

GID1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei134 – 1341Gibberellin1 Publication
Active sitei198 – 1981PROSITE-ProRule annotation
Binding sitei198 – 1981Gibberellin1 Publication
Binding sitei250 – 2501Gibberellin1 Publication
Active sitei296 – 2961By similarity
Binding sitei327 – 3271Gibberellin; via amide nitrogen1 Publication

GO - Molecular functioni

  • gibberellin binding Source: UniProtKB
  • hydrolase activity Source: GO_Central

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Receptor

Keywords - Biological processi

Gibberellin signaling pathway

Protein family/group databases

ESTHERiorysa-gid1. Plant_carboxylesterase.

Names & Taxonomyi

Protein namesi
Recommended name:
Gibberellin receptor GID11 Publication (EC:3.-.-.-Curated)
Alternative name(s):
Gibberellin-insensitive dwarf protein 11 Publication
Protein GIBBERELLIN INSENSITIVE DWARF11 Publication
Gene namesi
Name:GID11 Publication
Ordered Locus Names:Os05g0407500Imported, LOC_Os05g33730Curated
ORF Names:OJ1657_H11.10Imported, P0040B10.6Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 5

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Severe dwarf phenotype with wide and dark-green leaf blades. Plants insensitive to gibberellic acid (GA).1 Publication

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi196 – 1961G → D in gid1-1; abolishes binding to GA and ability to degrade SLR1. 1 Publication
Mutagenesisi251 – 2511R → T in gid1-2; abolishes binding to GA and ability to degrade SLR1. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 354354Gibberellin receptor GID1PRO_0000071557Add
BLAST

Proteomic databases

PaxDbiQ6L545.

Expressioni

Gene expression databases

ExpressionAtlasiQ6L545. baseline and differential.
GenevisibleiQ6L545. OS.

Interactioni

Subunit structurei

Interacts with the DELLA protein SLR1 in a GA-dependent manner, resulting in subsequent SLR1 degradation.3 Publications

Protein-protein interaction databases

BioGridi807801. 2 interactions.
DIPiDIP-59773N.
STRINGi39947.LOC_Os05g33730.1.

Structurei

Secondary structure

1
354
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi18 – 3417Combined sources
Helixi43 – 497Combined sources
Beta strandi63 – 719Combined sources
Turni72 – 754Combined sources
Beta strandi76 – 838Combined sources
Helixi102 – 1054Combined sources
Beta strandi109 – 1113Combined sources
Beta strandi114 – 1196Combined sources
Turni123 – 1253Combined sources
Helixi132 – 14514Combined sources
Beta strandi147 – 1526Combined sources
Turni157 – 1593Combined sources
Helixi164 – 17815Combined sources
Turni180 – 1823Combined sources
Turni185 – 1884Combined sources
Beta strandi189 – 1979Combined sources
Helixi200 – 21314Combined sources
Beta strandi220 – 2256Combined sources
Helixi235 – 2406Combined sources
Turni241 – 2433Combined sources
Helixi248 – 25811Combined sources
Turni268 – 2703Combined sources
Beta strandi288 – 2936Combined sources
Helixi299 – 31113Combined sources
Beta strandi316 – 3216Combined sources
Helixi328 – 3303Combined sources
Helixi335 – 35218Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3EBLX-ray1.90A/B/C/D/E/F2-354[»]
3ED1X-ray1.90A/B/C/D/E/F2-354[»]
ProteinModelPortaliQ6L545.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6L545.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni122 – 1232Gibberellin binding

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi120 – 1223Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion holeBy similarity

Sequence similaritiesi

Belongs to the 'GDXG' lipolytic enzyme family.Curated

Phylogenomic databases

eggNOGiKOG1515. Eukaryota.
COG0657. LUCA.
HOGENOMiHOG000152323.
InParanoidiQ6L545.
OMAiAVPIHTW.
OrthoDBiEOG09360EOQ.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR013094. AB_hydrolase_3.
IPR002168. Lipase_GDXG_HIS_AS.
IPR033140. Lipase_GDXG_put_SER_AS.
[Graphical view]
PfamiPF07859. Abhydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS01173. LIPASE_GDXG_HIS. 1 hit.
PS01174. LIPASE_GDXG_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6L545-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSDEVNRN ECKTVVPLHT WVLISNFKLS YNILRRADGT FERDLGEYLD
60 70 80 90 100
RRVPANARPL EGVSSFDHII DQSVGLEVRI YRAAAEGDAE EGAAAVTRPI
110 120 130 140 150
LEFLTDAPAA EPFPVIIFFH GGSFVHSSAS STIYDSLCRR FVKLSKGVVV
160 170 180 190 200
SVNYRRAPEH RYPCAYDDGW TALKWVMSQP FMRSGGDAQA RVFLSGDSSG
210 220 230 240 250
GNIAHHVAVR AADEGVKVCG NILLNAMFGG TERTESERRL DGKYFVTLQD
260 270 280 290 300
RDWYWKAYLP EDADRDHPAC NPFGPNGRRL GGLPFAKSLI IVSGLDLTCD
310 320 330 340 350
RQLAYADALR EDGHHVKVVQ CENATVGFYL LPNTVHYHEV MEEISDFLNA

NLYY
Length:354
Mass (Da):39,457
Last modified:October 25, 2004 - v1
Checksum:iEF98C64CE20B96F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB211399 mRNA. Translation: BAE45340.1.
AC105319 Genomic DNA. Translation: AAT38036.1.
AC137928 Genomic DNA. Translation: AAV59435.1.
AP008211 Genomic DNA. Translation: BAF17434.1.
AP014961 Genomic DNA. Translation: BAS93968.1.
CM000142 Genomic DNA. Translation: EEE63694.1.
AK074026 mRNA. Translation: BAG93769.1.
RefSeqiXP_015639961.1. XM_015784475.1.
UniGeneiOs.100392.

Genome annotation databases

EnsemblPlantsiOS05T0407500-01; OS05T0407500-01; OS05G0407500.
GeneIDi4338764.
GrameneiOS05T0407500-01; OS05T0407500-01; OS05G0407500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB211399 mRNA. Translation: BAE45340.1.
AC105319 Genomic DNA. Translation: AAT38036.1.
AC137928 Genomic DNA. Translation: AAV59435.1.
AP008211 Genomic DNA. Translation: BAF17434.1.
AP014961 Genomic DNA. Translation: BAS93968.1.
CM000142 Genomic DNA. Translation: EEE63694.1.
AK074026 mRNA. Translation: BAG93769.1.
RefSeqiXP_015639961.1. XM_015784475.1.
UniGeneiOs.100392.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3EBLX-ray1.90A/B/C/D/E/F2-354[»]
3ED1X-ray1.90A/B/C/D/E/F2-354[»]
ProteinModelPortaliQ6L545.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi807801. 2 interactions.
DIPiDIP-59773N.
STRINGi39947.LOC_Os05g33730.1.

Protein family/group databases

ESTHERiorysa-gid1. Plant_carboxylesterase.

Proteomic databases

PaxDbiQ6L545.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS05T0407500-01; OS05T0407500-01; OS05G0407500.
GeneIDi4338764.
GrameneiOS05T0407500-01; OS05T0407500-01; OS05G0407500.

Phylogenomic databases

eggNOGiKOG1515. Eukaryota.
COG0657. LUCA.
HOGENOMiHOG000152323.
InParanoidiQ6L545.
OMAiAVPIHTW.
OrthoDBiEOG09360EOQ.

Miscellaneous databases

EvolutionaryTraceiQ6L545.

Gene expression databases

ExpressionAtlasiQ6L545. baseline and differential.
GenevisibleiQ6L545. OS.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR013094. AB_hydrolase_3.
IPR002168. Lipase_GDXG_HIS_AS.
IPR033140. Lipase_GDXG_put_SER_AS.
[Graphical view]
PfamiPF07859. Abhydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS01173. LIPASE_GDXG_HIS. 1 hit.
PS01174. LIPASE_GDXG_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGID1_ORYSJ
AccessioniPrimary (citable) accession number: Q6L545
Secondary accession number(s): Q0DI89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 25, 2004
Last modified: September 7, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.