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Protein

Gibberellin receptor GID1

Gene

GID1

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei134Gibberellin1 Publication1
Active sitei198PROSITE-ProRule annotation1
Binding sitei198Gibberellin1 Publication1
Binding sitei250Gibberellin1 Publication1
Active sitei296By similarity1
Binding sitei327Gibberellin; via amide nitrogen1 Publication1

GO - Molecular functioni

  • gibberellin binding Source: UniProtKB
  • hydrolase activity Source: GO_Central

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Receptor

Keywords - Biological processi

Gibberellin signaling pathway

Protein family/group databases

ESTHERiorysa-gid1. Plant_carboxylesterase.

Names & Taxonomyi

Protein namesi
Recommended name:
Gibberellin receptor GID11 Publication (EC:3.-.-.-Curated)
Alternative name(s):
Gibberellin-insensitive dwarf protein 11 Publication
Protein GIBBERELLIN INSENSITIVE DWARF11 Publication
Gene namesi
Name:GID11 Publication
Ordered Locus Names:Os05g0407500Imported, LOC_Os05g33730Curated
ORF Names:OJ1657_H11.10Imported, P0040B10.6Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 5

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Severe dwarf phenotype with wide and dark-green leaf blades. Plants insensitive to gibberellic acid (GA).1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi196G → D in gid1-1; abolishes binding to GA and ability to degrade SLR1. 1 Publication1
Mutagenesisi251R → T in gid1-2; abolishes binding to GA and ability to degrade SLR1. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000715571 – 354Gibberellin receptor GID1Add BLAST354

Proteomic databases

PaxDbiQ6L545.

Expressioni

Gene expression databases

GenevisibleiQ6L545. OS.

Interactioni

Subunit structurei

Interacts with the DELLA protein SLR1 in a GA-dependent manner, resulting in subsequent SLR1 degradation.3 Publications

Protein-protein interaction databases

BioGridi807801. 4 interactors.
DIPiDIP-59773N.
STRINGi39947.LOC_Os05g33730.1.

Structurei

Secondary structure

1354
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi18 – 34Combined sources17
Helixi43 – 49Combined sources7
Beta strandi63 – 71Combined sources9
Turni72 – 75Combined sources4
Beta strandi76 – 83Combined sources8
Helixi102 – 105Combined sources4
Beta strandi109 – 111Combined sources3
Beta strandi114 – 119Combined sources6
Turni123 – 125Combined sources3
Helixi132 – 145Combined sources14
Beta strandi147 – 152Combined sources6
Turni157 – 159Combined sources3
Helixi164 – 178Combined sources15
Turni180 – 182Combined sources3
Turni185 – 188Combined sources4
Beta strandi189 – 197Combined sources9
Helixi200 – 213Combined sources14
Beta strandi220 – 225Combined sources6
Helixi235 – 240Combined sources6
Turni241 – 243Combined sources3
Helixi248 – 258Combined sources11
Turni268 – 270Combined sources3
Beta strandi288 – 293Combined sources6
Helixi299 – 311Combined sources13
Beta strandi316 – 321Combined sources6
Helixi328 – 330Combined sources3
Helixi335 – 352Combined sources18

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EBLX-ray1.90A/B/C/D/E/F2-354[»]
3ED1X-ray1.90A/B/C/D/E/F2-354[»]
ProteinModelPortaliQ6L545.
SMRiQ6L545.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6L545.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni122 – 123Gibberellin binding2

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi120 – 122Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion holeBy similarity3

Sequence similaritiesi

Belongs to the 'GDXG' lipolytic enzyme family.Curated

Phylogenomic databases

eggNOGiKOG1515. Eukaryota.
COG0657. LUCA.
HOGENOMiHOG000152323.
InParanoidiQ6L545.
KOiK14493.
OMAiAVPIHTW.
OrthoDBiEOG09360EOQ.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR013094. AB_hydrolase_3.
IPR002168. Lipase_GDXG_HIS_AS.
IPR033140. Lipase_GDXG_put_SER_AS.
[Graphical view]
PfamiPF07859. Abhydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS01173. LIPASE_GDXG_HIS. 1 hit.
PS01174. LIPASE_GDXG_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6L545-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSDEVNRN ECKTVVPLHT WVLISNFKLS YNILRRADGT FERDLGEYLD
60 70 80 90 100
RRVPANARPL EGVSSFDHII DQSVGLEVRI YRAAAEGDAE EGAAAVTRPI
110 120 130 140 150
LEFLTDAPAA EPFPVIIFFH GGSFVHSSAS STIYDSLCRR FVKLSKGVVV
160 170 180 190 200
SVNYRRAPEH RYPCAYDDGW TALKWVMSQP FMRSGGDAQA RVFLSGDSSG
210 220 230 240 250
GNIAHHVAVR AADEGVKVCG NILLNAMFGG TERTESERRL DGKYFVTLQD
260 270 280 290 300
RDWYWKAYLP EDADRDHPAC NPFGPNGRRL GGLPFAKSLI IVSGLDLTCD
310 320 330 340 350
RQLAYADALR EDGHHVKVVQ CENATVGFYL LPNTVHYHEV MEEISDFLNA

NLYY
Length:354
Mass (Da):39,457
Last modified:October 25, 2004 - v1
Checksum:iEF98C64CE20B96F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB211399 mRNA. Translation: BAE45340.1.
AC105319 Genomic DNA. Translation: AAT38036.1.
AC137928 Genomic DNA. Translation: AAV59435.1.
AP008211 Genomic DNA. Translation: BAF17434.1.
AP014961 Genomic DNA. Translation: BAS93968.1.
CM000142 Genomic DNA. Translation: EEE63694.1.
AK074026 mRNA. Translation: BAG93769.1.
RefSeqiXP_015639961.1. XM_015784475.1.
UniGeneiOs.100392.

Genome annotation databases

EnsemblPlantsiOS05T0407500-01; OS05T0407500-01; OS05G0407500.
GeneIDi4338764.
GrameneiOS05T0407500-01; OS05T0407500-01; OS05G0407500.
KEGGiosa:4338764.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB211399 mRNA. Translation: BAE45340.1.
AC105319 Genomic DNA. Translation: AAT38036.1.
AC137928 Genomic DNA. Translation: AAV59435.1.
AP008211 Genomic DNA. Translation: BAF17434.1.
AP014961 Genomic DNA. Translation: BAS93968.1.
CM000142 Genomic DNA. Translation: EEE63694.1.
AK074026 mRNA. Translation: BAG93769.1.
RefSeqiXP_015639961.1. XM_015784475.1.
UniGeneiOs.100392.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EBLX-ray1.90A/B/C/D/E/F2-354[»]
3ED1X-ray1.90A/B/C/D/E/F2-354[»]
ProteinModelPortaliQ6L545.
SMRiQ6L545.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi807801. 4 interactors.
DIPiDIP-59773N.
STRINGi39947.LOC_Os05g33730.1.

Protein family/group databases

ESTHERiorysa-gid1. Plant_carboxylesterase.

Proteomic databases

PaxDbiQ6L545.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS05T0407500-01; OS05T0407500-01; OS05G0407500.
GeneIDi4338764.
GrameneiOS05T0407500-01; OS05T0407500-01; OS05G0407500.
KEGGiosa:4338764.

Phylogenomic databases

eggNOGiKOG1515. Eukaryota.
COG0657. LUCA.
HOGENOMiHOG000152323.
InParanoidiQ6L545.
KOiK14493.
OMAiAVPIHTW.
OrthoDBiEOG09360EOQ.

Miscellaneous databases

EvolutionaryTraceiQ6L545.

Gene expression databases

GenevisibleiQ6L545. OS.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR013094. AB_hydrolase_3.
IPR002168. Lipase_GDXG_HIS_AS.
IPR033140. Lipase_GDXG_put_SER_AS.
[Graphical view]
PfamiPF07859. Abhydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS01173. LIPASE_GDXG_HIS. 1 hit.
PS01174. LIPASE_GDXG_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGID1_ORYSJ
AccessioniPrimary (citable) accession number: Q6L545
Secondary accession number(s): Q0DI89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 25, 2004
Last modified: November 30, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.