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Q6L4R7

- P2C53_ORYSJ

UniProt

Q6L4R7 - P2C53_ORYSJ

Protein

Probable protein phosphatase 2C 53

Gene

Os05g0592800

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi180 – 1801Manganese 1By similarity
    Metal bindingi180 – 1801Manganese 2By similarity
    Metal bindingi181 – 1811Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi362 – 3621Manganese 2By similarity
    Metal bindingi426 – 4261Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 53 (EC:3.1.3.16)
    Short name:
    OsPP2C53
    Gene namesi
    Ordered Locus Names:Os05g0592800, LOC_Os05g51510
    ORF Names:OsJ_018965, P0663C08.11
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 5

    Organism-specific databases

    GrameneiQ6L4R7.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2929Sequence AnalysisAdd
    BLAST
    Chaini30 – 445416Probable protein phosphatase 2C 53PRO_0000363300Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ6L4R7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini123 – 428306PP2C-likeAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi5 – 113109Ala-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG0631.
    KOiK14497.
    OMAiCFLKVDS.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q6L4R7-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEDLALPAAP PAPTLSFTLL AAAAAVAEAM EEALGAALPP LTAPVPAPGD    50
    DSACGSPCSV ASDCSSVASA DFEGFAELGT SLLAGPAVLF DDLTAASVAV 100
    AEAAEPRAVG ATARSVFAMD CVPLWGLESI CGRRPEMEDD YAVVPRFFDL 150
    PLWMVAGDAA VDGLDRASFR LPAHFFAVYD GHGGVQVANY CRKRIHAVLT 200
    EELRRAEDDA CGSDLSGLES KKLWEKAFVD CFSRVDAEVG GNAASGAPPV 250
    APDTVGSTAV VAVVCSSHVI VANCGDSRAV LCRGKQPLPL SLDHKPNRED 300
    EYARIEALGG KVIQWNGYRV LGVLAMSRSI GDKYLKPYII PVPEVTVVAR 350
    AKDDDCLILA SDGLWDVMSN EEVCDAARKR ILLWHKKNAA TASTSSAQIS 400
    GDSSDPAAQA AADYLSKLAL QKGSKDNITV VVIDLKAHRK FKSKA 445
    Length:445
    Mass (Da):46,684
    Last modified:July 5, 2004 - v1
    Checksum:iE06D4D4A57E97FC1
    GO
    Isoform 2 (identifier: Q6L4R7-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-144: Missing.
         145-186: PRFFDLPLWM...AVYDGHGGVQ → MPWSRDFSTF...PISSPSTMAT

    Note: No experimental confirmation available.

    Show »
    Length:301
    Mass (Da):32,306
    Checksum:i3EB37EADBA7F3952
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 144144Missing in isoform 2. 1 PublicationVSP_036273Add
    BLAST
    Alternative sequencei145 – 18642PRFFD…HGGVQ → MPWSRDFSTFLCGWLPATRQ STASTGPPSAFQPISSPSTM AT in isoform 2. 1 PublicationVSP_036274Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC130728 Genomic DNA. Translation: AAT44303.1.
    AP008211 Genomic DNA. Translation: BAF18412.1.
    CM000142 Genomic DNA. Translation: EAZ35482.1.
    AK067627 mRNA. Translation: BAG90506.1.
    AK070388 mRNA. Translation: BAG91921.1.
    RefSeqiNP_001056498.1. NM_001063033.1. [Q6L4R7-1]
    UniGeneiOs.52518.

    Genome annotation databases

    EnsemblPlantsiOS05T0592800-02; OS05T0592800-02; OS05G0592800. [Q6L4R7-1]
    OS05T0592800-03; OS05T0592800-03; OS05G0592800. [Q6L4R7-1]
    GeneIDi4339797.
    KEGGiosa:4339797.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC130728 Genomic DNA. Translation: AAT44303.1 .
    AP008211 Genomic DNA. Translation: BAF18412.1 .
    CM000142 Genomic DNA. Translation: EAZ35482.1 .
    AK067627 mRNA. Translation: BAG90506.1 .
    AK070388 mRNA. Translation: BAG91921.1 .
    RefSeqi NP_001056498.1. NM_001063033.1. [Q6L4R7-1 ]
    UniGenei Os.52518.

    3D structure databases

    ProteinModelPortali Q6L4R7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS05T0592800-02 ; OS05T0592800-02 ; OS05G0592800 . [Q6L4R7-1 ]
    OS05T0592800-03 ; OS05T0592800-03 ; OS05G0592800 . [Q6L4R7-1 ]
    GeneIDi 4339797.
    KEGGi osa:4339797.

    Organism-specific databases

    Gramenei Q6L4R7.

    Phylogenomic databases

    eggNOGi COG0631.
    KOi K14497.
    OMAi CFLKVDS.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "The genomes of Oryza sativa: a history of duplications."
      Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
      , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
      PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    5. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Strain: cv. Nipponbare.
    6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C53_ORYSJ
    AccessioniPrimary (citable) accession number: Q6L4R7
    Secondary accession number(s): B7EHS4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 3, 2009
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3