Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable protein phosphatase 2C 53

Gene

Os05g0592800

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi180 – 1801Manganese 1By similarity
Metal bindingi180 – 1801Manganese 2By similarity
Metal bindingi181 – 1811Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi362 – 3621Manganese 2By similarity
Metal bindingi426 – 4261Manganese 2By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 53 (EC:3.1.3.16)
Short name:
OsPP2C53
Gene namesi
Ordered Locus Names:Os05g0592800, LOC_Os05g51510
ORF Names:OsJ_018965, P0663C08.11
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 5

Organism-specific databases

GrameneiQ6L4R7.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929Sequence AnalysisAdd
BLAST
Chaini30 – 445416Probable protein phosphatase 2C 53PRO_0000363300Add
BLAST

Expressioni

Gene expression databases

ExpressionAtlasiQ6L4R7. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os05g51510.1.

Structurei

3D structure databases

ProteinModelPortaliQ6L4R7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini124 – 435312PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi5 – 113109Ala-richAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiQ6L4R7.
KOiK14497.
OMAiLWEKAFV.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q6L4R7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEDLALPAAP PAPTLSFTLL AAAAAVAEAM EEALGAALPP LTAPVPAPGD
60 70 80 90 100
DSACGSPCSV ASDCSSVASA DFEGFAELGT SLLAGPAVLF DDLTAASVAV
110 120 130 140 150
AEAAEPRAVG ATARSVFAMD CVPLWGLESI CGRRPEMEDD YAVVPRFFDL
160 170 180 190 200
PLWMVAGDAA VDGLDRASFR LPAHFFAVYD GHGGVQVANY CRKRIHAVLT
210 220 230 240 250
EELRRAEDDA CGSDLSGLES KKLWEKAFVD CFSRVDAEVG GNAASGAPPV
260 270 280 290 300
APDTVGSTAV VAVVCSSHVI VANCGDSRAV LCRGKQPLPL SLDHKPNRED
310 320 330 340 350
EYARIEALGG KVIQWNGYRV LGVLAMSRSI GDKYLKPYII PVPEVTVVAR
360 370 380 390 400
AKDDDCLILA SDGLWDVMSN EEVCDAARKR ILLWHKKNAA TASTSSAQIS
410 420 430 440
GDSSDPAAQA AADYLSKLAL QKGSKDNITV VVIDLKAHRK FKSKA
Length:445
Mass (Da):46,684
Last modified:July 5, 2004 - v1
Checksum:iE06D4D4A57E97FC1
GO
Isoform 2 (identifier: Q6L4R7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-144: Missing.
     145-186: PRFFDLPLWM...AVYDGHGGVQ → MPWSRDFSTF...PISSPSTMAT

Note: No experimental confirmation available.
Show »
Length:301
Mass (Da):32,306
Checksum:i3EB37EADBA7F3952
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 144144Missing in isoform 2. 1 PublicationVSP_036273Add
BLAST
Alternative sequencei145 – 18642PRFFD…HGGVQ → MPWSRDFSTFLCGWLPATRQ STASTGPPSAFQPISSPSTM AT in isoform 2. 1 PublicationVSP_036274Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130728 Genomic DNA. Translation: AAT44303.1.
AP008211 Genomic DNA. Translation: BAF18412.1.
CM000142 Genomic DNA. Translation: EAZ35482.1.
AK067627 mRNA. Translation: BAG90506.1.
AK070388 mRNA. Translation: BAG91921.1.
RefSeqiNP_001056498.1. NM_001063033.1. [Q6L4R7-1]
UniGeneiOs.52518.

Genome annotation databases

EnsemblPlantsiOS05T0592800-02; OS05T0592800-02; OS05G0592800. [Q6L4R7-1]
OS05T0592800-03; OS05T0592800-03; OS05G0592800. [Q6L4R7-1]
GeneIDi4339797.
KEGGiosa:4339797.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130728 Genomic DNA. Translation: AAT44303.1.
AP008211 Genomic DNA. Translation: BAF18412.1.
CM000142 Genomic DNA. Translation: EAZ35482.1.
AK067627 mRNA. Translation: BAG90506.1.
AK070388 mRNA. Translation: BAG91921.1.
RefSeqiNP_001056498.1. NM_001063033.1. [Q6L4R7-1]
UniGeneiOs.52518.

3D structure databases

ProteinModelPortaliQ6L4R7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os05g51510.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS05T0592800-02; OS05T0592800-02; OS05G0592800. [Q6L4R7-1]
OS05T0592800-03; OS05T0592800-03; OS05G0592800. [Q6L4R7-1]
GeneIDi4339797.
KEGGiosa:4339797.

Organism-specific databases

GrameneiQ6L4R7.

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiQ6L4R7.
KOiK14497.
OMAiLWEKAFV.

Gene expression databases

ExpressionAtlasiQ6L4R7. baseline.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  5. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Strain: cv. Nipponbare.
  6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C53_ORYSJ
AccessioniPrimary (citable) accession number: Q6L4R7
Secondary accession number(s): B7EHS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: July 5, 2004
Last modified: June 24, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.