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Protein

Probable protein phosphatase 2C 48

Gene

Os05g0358500

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi90 – 901Manganese 1By similarity
Metal bindingi90 – 901Manganese 2By similarity
Metal bindingi91 – 911Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi293 – 2931Manganese 2By similarity
Metal bindingi339 – 3391Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 48 (EC:3.1.3.16)
Short name:
OsPP2C48
Gene namesi
Ordered Locus Names:Os05g0358500, LOC_Os05g29030
ORF Names:OJ1045_C06.13, OSJNBa0009L15.3
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763 Componenti: Chromosome 5

Organism-specific databases

GrameneiQ6L482.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 353353Probable protein phosphatase 2C 48PRO_0000363295Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini54 – 348295PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi31 – 388Poly-Ala

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233897.
InParanoidiQ6L482.
OMAiLCHWQEA.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q6L482-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MRHISSLLQG LARSLSVGKE RKGGDGDDGK AAAATATAVL RTSGTLWGEG
60 70 80 90 100
SETFAAVCSR RGEKGINQDC SIVCEGFGCE EGSVLCGIFD GHGQWGHYVA
110 120 130 140 150
KAVRESLPPA LLRRWREAVT LAALIDGGEK RLCECRPDLW RQSYLAACAA
160 170 180 190 200
VDAELRASRR LDAVHSGCTA LSLVKHGDLL VVANVGDSRA VLATASPDDG
210 220 230 240 250
GGARLAAVQL TVDFKPNLPQ ERERIMECNG RVQCLADEPG VHRVWRPDRE
260 270 280 290 300
GPGLAMSRAF GDYCVKDYGV ISAPEVTHRR ITAQDHFVIL ATDGVWDVVS
310 320 330 340 350
NEEAVQIVAS APEREKAAKR LVEFAVRAWR RKRRGIAVDD CSAICLFFHS

PPS
Length:353
Mass (Da):38,101
Last modified:July 5, 2004 - v1
Checksum:i08013ADEAE50D4C2
GO
Isoform 2 (identifier: Q6L482-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     295-353: VWDVVSNEEA...ICLFFHSPPS → DKHLNLFVFV...TRRRQCRRRR

Note: Derived from EST data. No experimental confirmation available.

Show »
Length:391
Mass (Da):41,972
Checksum:i8FAA97D0189CE654
GO

Sequence cautioni

The sequence AK100777 differs from that shown. Reason: Frameshift at position 277. Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei295 – 35359VWDVV…HSPPS → DKHLNLFVFVCAAGVGRGVE RGGGADRGVGAGEGEGGEAA RRVRRPGMEAQAPGHRRRRL LGDLPLLPLAAVLNNTHADT HAANKNRTRRRQCRRRR in isoform 2. CuratedVSP_036270Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136999 Genomic DNA. Translation: AAT38039.1.
AC104272 Genomic DNA. Translation: AAV43855.1.
AP008211 Genomic DNA. Translation: BAF17217.1.
AK100777 mRNA. No translation available.
RefSeqiNP_001055303.1. NM_001061838.1. [Q6L482-1]
UniGeneiOs.9646.

Genome annotation databases

EnsemblPlantsiOS05T0358500-01; OS05T0358500-01; OS05G0358500. [Q6L482-1]
OS05T0358500-02; OS05T0358500-02; OS05G0358500. [Q6L482-1]
GeneIDi4338531.
KEGGiosa:4338531.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136999 Genomic DNA. Translation: AAT38039.1.
AC104272 Genomic DNA. Translation: AAV43855.1.
AP008211 Genomic DNA. Translation: BAF17217.1.
AK100777 mRNA. No translation available.
RefSeqiNP_001055303.1. NM_001061838.1. [Q6L482-1]
UniGeneiOs.9646.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS05T0358500-01; OS05T0358500-01; OS05G0358500. [Q6L482-1]
OS05T0358500-02; OS05T0358500-02; OS05G0358500. [Q6L482-1]
GeneIDi4338531.
KEGGiosa:4338531.

Organism-specific databases

GrameneiQ6L482.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233897.
InParanoidiQ6L482.
OMAiLCHWQEA.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: cv. Nipponbare.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C48_ORYSJ
AccessioniPrimary (citable) accession number: Q6L482
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: July 5, 2004
Last modified: April 1, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.