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Q6L482

- P2C48_ORYSJ

UniProt

Q6L482 - P2C48_ORYSJ

Protein

Probable protein phosphatase 2C 48

Gene

Os05g0358500

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi90 – 901Manganese 1By similarity
    Metal bindingi90 – 901Manganese 2By similarity
    Metal bindingi91 – 911Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi293 – 2931Manganese 2By similarity
    Metal bindingi339 – 3391Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    GO - Biological processi

    1. response to water deprivation Source: EnsemblPlants/Gramene

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 48 (EC:3.1.3.16)
    Short name:
    OsPP2C48
    Gene namesi
    Ordered Locus Names:Os05g0358500, LOC_Os05g29030
    ORF Names:OJ1045_C06.13, OSJNBa0009L15.3
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 5

    Organism-specific databases

    GrameneiQ6L482.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: EnsemblPlants/Gramene
    2. nucleus Source: EnsemblPlants/Gramene

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 353353Probable protein phosphatase 2C 48PRO_0000363295Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ6L482.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini53 – 321269PP2C-likeAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi31 – 388Poly-Ala

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233897.
    OMAiCATVDQE.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q6L482-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MRHISSLLQG LARSLSVGKE RKGGDGDDGK AAAATATAVL RTSGTLWGEG    50
    SETFAAVCSR RGEKGINQDC SIVCEGFGCE EGSVLCGIFD GHGQWGHYVA 100
    KAVRESLPPA LLRRWREAVT LAALIDGGEK RLCECRPDLW RQSYLAACAA 150
    VDAELRASRR LDAVHSGCTA LSLVKHGDLL VVANVGDSRA VLATASPDDG 200
    GGARLAAVQL TVDFKPNLPQ ERERIMECNG RVQCLADEPG VHRVWRPDRE 250
    GPGLAMSRAF GDYCVKDYGV ISAPEVTHRR ITAQDHFVIL ATDGVWDVVS 300
    NEEAVQIVAS APEREKAAKR LVEFAVRAWR RKRRGIAVDD CSAICLFFHS 350
    PPS 353
    Length:353
    Mass (Da):38,101
    Last modified:July 5, 2004 - v1
    Checksum:i08013ADEAE50D4C2
    GO
    Isoform 2 (identifier: Q6L482-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         295-353: VWDVVSNEEA...ICLFFHSPPS → DKHLNLFVFV...TRRRQCRRRR

    Note: Derived from EST data. No experimental confirmation available.

    Show »
    Length:391
    Mass (Da):41,972
    Checksum:i8FAA97D0189CE654
    GO

    Sequence cautioni

    The sequence AK100777 differs from that shown. Reason: Frameshift at position 277.

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei295 – 35359VWDVV…HSPPS → DKHLNLFVFVCAAGVGRGVE RGGGADRGVGAGEGEGGEAA RRVRRPGMEAQAPGHRRRRL LGDLPLLPLAAVLNNTHADT HAANKNRTRRRQCRRRR in isoform 2. CuratedVSP_036270Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC136999 Genomic DNA. Translation: AAT38039.1.
    AC104272 Genomic DNA. Translation: AAV43855.1.
    AP008211 Genomic DNA. Translation: BAF17217.1.
    AK100777 mRNA. No translation available.
    RefSeqiNP_001055303.1. NM_001061838.1. [Q6L482-1]
    UniGeneiOs.9646.

    Genome annotation databases

    EnsemblPlantsiOS05T0358500-01; OS05T0358500-01; OS05G0358500. [Q6L482-1]
    OS05T0358500-02; OS05T0358500-02; OS05G0358500. [Q6L482-1]
    GeneIDi4338531.
    KEGGiosa:4338531.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC136999 Genomic DNA. Translation: AAT38039.1 .
    AC104272 Genomic DNA. Translation: AAV43855.1 .
    AP008211 Genomic DNA. Translation: BAF17217.1 .
    AK100777 mRNA. No translation available.
    RefSeqi NP_001055303.1. NM_001061838.1. [Q6L482-1 ]
    UniGenei Os.9646.

    3D structure databases

    ProteinModelPortali Q6L482.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS05T0358500-01 ; OS05T0358500-01 ; OS05G0358500 . [Q6L482-1 ]
    OS05T0358500-02 ; OS05T0358500-02 ; OS05G0358500 . [Q6L482-1 ]
    GeneIDi 4338531.
    KEGGi osa:4338531.

    Organism-specific databases

    Gramenei Q6L482.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233897.
    OMAi CATVDQE.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    3. "The rice annotation project database (RAP-DB): 2008 update."
      The rice annotation project (RAP)
      Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: cv. Nipponbare.
    4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Strain: cv. Nipponbare.
    5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C48_ORYSJ
    AccessioniPrimary (citable) accession number: Q6L482
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 10, 2009
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3