ID   Q6L2T2_PICTO            Unreviewed;      1205 AA.
AC   Q6L2T2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:AAT42720.1};
DE            EC=2.7.11.1 {ECO:0000313|EMBL:AAT42720.1};
GN   OrderedLocusNames=PTO0135 {ECO:0000313|EMBL:AAT42720.1};
OS   Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC
OS   100828 / KAW 2/3).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Picrophilaceae; Picrophilus.
OX   NCBI_TaxID=1122961 {ECO:0000313|EMBL:AAT42720.1, ECO:0000313|Proteomes:UP000000438};
RN   [1] {ECO:0000313|EMBL:AAT42720.1, ECO:0000313|Proteomes:UP000000438}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828
RC   {ECO:0000313|Proteomes:UP000000438};
RX   PubMed=15184674; DOI=10.1073/pnas.0401356101;
RA   Futterer O., Angelov A., Liesegang H., Gottschalk G., Schleper C.,
RA   Schepers B., Dock C., Antranikian G., Liebl W.;
RT   "Genome sequence of Picrophilus torridus and its implications for life
RT   around pH 0.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096(2004).
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DR   EMBL; AE017261; AAT42720.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6L2T2; -.
DR   STRING; 263820.PTO0135; -.
DR   PaxDb; 263820-PTO0135; -.
DR   KEGG; pto:PTO0135; -.
DR   eggNOG; arCOG03682; Archaea.
DR   HOGENOM; CLU_270281_0_0_2; -.
DR   InParanoid; Q6L2T2; -.
DR   Proteomes; UP000000438; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR43671:SF13; LD04361P; 1.
DR   PANTHER; PTHR43671; SERINE/THREONINE-PROTEIN KINASE NEK; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:AAT42720.1};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:AAT42720.1};
KW   Transferase {ECO:0000313|EMBL:AAT42720.1}.
FT   DOMAIN          10..267
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   1205 AA;  138701 MW;  FF7877E6C39863CF CRC64;
     MDETFGNNRY SVIKKLGEGG KGIVYKCIDN NLNRIVALKL IKSESLDDES YSRIIREAET
     TARLSHPNIV SIYDMQKEDN RFFMVIEYID GKDLLDYIDN KPLKLDEILS LIIPITSALS
     YAHKNGVLHR DIKPENIMVS KNGEPKLMDF GLAKALDRPG ITRAGTIVGT PAYLSPESAL
     GKESDNRSDL YSLGCVLYYM STGRPPFTIN DTIKLIYSHI HDYPAEPSKI NKDIPRQLDS
     IIMKLLRKNP DDRFQSADEL LYALKALEME NRPDNKKEII EKTDSYKDQS MLIGLDNIIS
     ELQSAVDSGL SGSGSIYLIT GESGQGKTRI LEKTMDYAVL RGTKSILLKG RESRMSTPNY
     LFTEMFREFF YEAPQQLVYK VCGDYGDVAV KILPELISKL GRINDYMSSE PDQARLRFYD
     GVIEIIKNMS IEYPVLMEID DINYADSGSL SIIDSIMDKL QSLRFVIIAT MSKSDSYNDE
     LDHIISNRIL NKMETKNLDR SQTAMLIASR LNEDVSKISD EFTDFIFVKT DGNPFYIEEV
     LKLLKDKKLI FRDEHGSWDR KPIEEIGIPS SIGSFIKERL SSLDDITMDI ISMASVIGYE
     FDVDVLESIS GIDENQFEKI IENSIKRKIV YERKTAPGEF RLFFSNPQLH DYLYENMSMF
     RKRKLHAKIA NAIESIYGDN NSAFFQDLAR HYLEAGNLQK ALDYNIKLAD NWSESFQFDQ
     AVKEYRRALE ILGEIHKPGK ESEMLRANLL YKISENAVFN NDISENDSIY LDEAIRIFDR
     YGEDKKIAES ILISSASYNK FDYYIDYTRS FLNRLYENKG DPEVIGIAST AIIGSLWYTA
     NVSEARKWGK KYIDYVRSIN YYDKYTIRCK EILLLVHPLN SYSDLDDIIK SYEEIAYEST
     NLLEKHPDDL ILLNTLSTLF NNFGTMMARM VFDLKKAEQA FDRGIQFAGK ISRGQKARLE
     ISKYEELFLS GNRDVVNRYF DMVFKSNSRD DFYIMVSKFG ELYFDYFHGD IDKTITLISE
     LEKIPSMQVL TSIPEVKVPV FVDNKKITEI YDYIEDIIKK IDGEITGDTI KGYIITLMHA
     VYVSSIANNS ENAIKYLSLI KNEYNKYGLW WIGSYMNIAE SYYQSYFGNR DAAKKLMNDS
     ALKFHEHGFD IYYGIYMYEL AVLYHMDGEQ EKCNMALDSA LSVFTPINFT LYIEKCLRLK
     ELLKA
//