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Protein
Submitted name:

Isocitrate dehydrogenase [NADP]

Gene

PTO0426

Organism
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. magnesium ion binding Source: InterPro
  3. NAD binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciPTOR263820:GHA3-441-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP]Imported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:PTO0426Imported
OrganismiPicrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)Imported
Taxonomic identifieri263820 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesPicrophilaceaePicrophilus
ProteomesiUP000000438: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi263820.PTO0426.

Structurei

3D structure databases

ProteinModelPortaliQ6L1Z1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0538.
KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 2 hits.
InterProiIPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6L1Z1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYIKLDGNHL IIPDDVTIGY IEGDGEGTEL TRAMINAVNS AIEIAYSGSK
60 70 80 90 100
SIEWKKIYIG REAYEKYGKY LPRESIEDIR KTVFVMKGPL SSNINGHDIN
110 120 130 140 150
INIKRILNLY TDVKCITGLP GLSEGKEIFI FSPSIDEVYH FSYDSEDSDM
160 170 180 190 200
LRQYLQQSFN ISIGGDSDIF LKGTSRYRII KIASKIAEIS SLYGIKRTLV
210 220 230 240 250
ADDYTGSHAP LWVYNTLNKM EMPVEIENLY NLYDEMTSES RFNIFIPDSR
260 270 280 290 300
LSSLIIKIIN ARTFFGAILG DFISLFESQS RPSFTEEGYD LADPTSFLLA
310 320 330 340 350
SSMMLRRLNF NDAALILRNA LNSVYSDGIL PASLNLNNGL KCSDFIDAIV

KRMKR
Length:355
Mass (Da):40,127
Last modified:July 5, 2004 - v1
Checksum:i48D4C0412A3C2771
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017261 Genomic DNA. Translation: AAT43011.1.
RefSeqiWP_011177227.1. NC_005877.1.
YP_023204.1. NC_005877.1.

Genome annotation databases

EnsemblBacteriaiAAT43011; AAT43011; PTO0426.
GeneIDi2845396.
KEGGipto:PTO0426.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017261 Genomic DNA. Translation: AAT43011.1.
RefSeqiWP_011177227.1. NC_005877.1.
YP_023204.1. NC_005877.1.

3D structure databases

ProteinModelPortaliQ6L1Z1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi263820.PTO0426.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT43011; AAT43011; PTO0426.
GeneIDi2845396.
KEGGipto:PTO0426.

Phylogenomic databases

eggNOGiCOG0538.
KOiK00031.

Enzyme and pathway databases

BioCyciPTOR263820:GHA3-441-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 2 hits.
InterProiIPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828Imported.

Entry informationi

Entry nameiQ6L1Z1_PICTO
AccessioniPrimary (citable) accession number: Q6L1Z1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 4, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.