Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

D-aminoacyl-tRNA deacylase

Gene

dtdA

Organism
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.UniRule annotation

Catalytic activityi

A D-aminoacyl-tRNA + H2O = a D-amino acid + tRNA.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 2 Zn2+ ions per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciPTOR263820:GHA3-634-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
D-aminoacyl-tRNA deacylaseUniRule annotation (EC:3.1.1.96UniRule annotation)
Alternative name(s):
D-tyrosyl-tRNA(Tyr) deacylase
Gene namesi
Name:dtdAUniRule annotation
Ordered Locus Names:PTO0612
OrganismiPicrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Taxonomic identifieri263820 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesPicrophilaceaePicrophilus
Proteomesi
  • UP000000438 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 255255D-aminoacyl-tRNA deacylasePRO_0000345226Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi263820.PTO0612.

Family & Domainsi

Sequence similaritiesi

Belongs to the DtdA deacylase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01616. Archaea.
COG1650. LUCA.
HOGENOMiHOG000015484.
KOiK09716.
OMAiVMICRHE.

Family and domain databases

HAMAPiMF_00562. Deacylase_DtdA. 1 hit.
InterProiIPR018033. Deacylase_DtdA_archaea.
IPR007508. DtdA.
[Graphical view]
PfamiPF04414. tRNA_deacylase. 1 hit.
[Graphical view]
PIRSFiPIRSF016210. UCP016210. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6L1F5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLIIASRMD EASMLMAEKI IDLYDFNRLN ENEYQKDGFK LMFIDDLHIY
60 70 80 90 100
HNMEKLDFDT LIFLSRHSSS AGVKSLTVHS IGNYRKAELG GYDNKTVLSA
110 120 130 140 150
PYEMSSSLRS IKELYNDDGY NITFEATHHG PYTKNRSYFI EIGTSGEDWH
160 170 180 190 200
NDKILEIMAR SVIEKNVKRF RSGIGIGGGH YAPKISDYFF NNDINIGHII
210 220 230 240 250
PKYVSETIKD NQIIESIENT ENCSFILIDW KGSPSRLRSL ALDAADKCSL

ELIKI
Length:255
Mass (Da):29,172
Last modified:July 22, 2008 - v2
Checksum:iE001574645CB713F
GO

Sequence cautioni

The sequence AAT43197 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017261 Genomic DNA. Translation: AAT43197.1. Different initiation.
RefSeqiWP_011177413.1. NC_005877.1.

Genome annotation databases

EnsemblBacteriaiAAT43197; AAT43197; PTO0612.
GeneIDi2844829.
KEGGipto:PTO0612.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017261 Genomic DNA. Translation: AAT43197.1. Different initiation.
RefSeqiWP_011177413.1. NC_005877.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi263820.PTO0612.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT43197; AAT43197; PTO0612.
GeneIDi2844829.
KEGGipto:PTO0612.

Phylogenomic databases

eggNOGiarCOG01616. Archaea.
COG1650. LUCA.
HOGENOMiHOG000015484.
KOiK09716.
OMAiVMICRHE.

Enzyme and pathway databases

BioCyciPTOR263820:GHA3-634-MONOMER.

Family and domain databases

HAMAPiMF_00562. Deacylase_DtdA. 1 hit.
InterProiIPR018033. Deacylase_DtdA_archaea.
IPR007508. DtdA.
[Graphical view]
PfamiPF04414. tRNA_deacylase. 1 hit.
[Graphical view]
PIRSFiPIRSF016210. UCP016210. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDTDA_PICTO
AccessioniPrimary (citable) accession number: Q6L1F5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 22, 2008
Last modified: September 7, 2016
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.