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Protein

DNA repair and recombination protein RadA

Gene

radA

Organism
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi114 – 1218ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPTOR263820:GHA3-767-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA repair and recombination protein RadAUniRule annotation
Gene namesi
Name:radAUniRule annotation
Ordered Locus Names:PTO0741
OrganismiPicrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Taxonomic identifieri263820 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesPicrophilaceaePicrophilus
Proteomesi
  • UP000000438 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323DNA repair and recombination protein RadAPRO_0000150101Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi263820.PTO0741.

Structurei

3D structure databases

ProteinModelPortaliQ6L126.
SMRiQ6L126. Positions 12-320.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic RecA-like protein family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00415. Archaea.
COG0468. LUCA.
HOGENOMiHOG000227426.
KOiK04483.
OMAiCQLPIDQ.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00348. RadA_arch. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013632. DNA_recomb/repair_Rad51_C.
IPR011938. DNA_recomb/repair_RadA.
IPR016467. DNA_recomb/repair_RecA-like.
IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFiPIRSF005856. Rad51. 1 hit.
SMARTiSM00382. AAA. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF47794. SSF47794. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02236. recomb_radA. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6L126-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKNDKEKRE LTIEDLPGVG DATAEKLRES GYDDIMTIAV ASPKDLAEIS
60 70 80 90 100
GIAEGAAIKI INAARKYADV GNFETGEEIL NKRKEIKKLT TGSSNLDNLL
110 120 130 140 150
GGGLETQSIT EFFGEFGSGK TQIMHQLAVN ATMPVEKNGF DSDVLIIDTE
160 170 180 190 200
NTFRPERIIQ MARAKDLDPD QTLERIHVAR AYNSHHQILL AEKAADMARE
210 220 230 240 250
YKIRLLIVDS LTSHFRSEYV GRGSLAERQQ LLNRHMHDLL KFGTIYNAVI
260 270 280 290 300
AVTNQVSANP AVFFGDPMNP IGGNIVGHTA TFRIYLRKAK AGKRIARLID
310 320
SPYLPEGETV ITITESGITD GEK
Length:323
Mass (Da):35,657
Last modified:July 5, 2004 - v1
Checksum:i1FC6827E640BD6F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017261 Genomic DNA. Translation: AAT43326.1.
RefSeqiWP_011177542.1. NC_005877.1.

Genome annotation databases

EnsemblBacteriaiAAT43326; AAT43326; PTO0741.
GeneIDi2845061.
KEGGipto:PTO0741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017261 Genomic DNA. Translation: AAT43326.1.
RefSeqiWP_011177542.1. NC_005877.1.

3D structure databases

ProteinModelPortaliQ6L126.
SMRiQ6L126. Positions 12-320.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi263820.PTO0741.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT43326; AAT43326; PTO0741.
GeneIDi2845061.
KEGGipto:PTO0741.

Phylogenomic databases

eggNOGiarCOG00415. Archaea.
COG0468. LUCA.
HOGENOMiHOG000227426.
KOiK04483.
OMAiCQLPIDQ.

Enzyme and pathway databases

BioCyciPTOR263820:GHA3-767-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00348. RadA_arch. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013632. DNA_recomb/repair_Rad51_C.
IPR011938. DNA_recomb/repair_RadA.
IPR016467. DNA_recomb/repair_RecA-like.
IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFiPIRSF005856. Rad51. 1 hit.
SMARTiSM00382. AAA. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF47794. SSF47794. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02236. recomb_radA. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRADA_PICTO
AccessioniPrimary (citable) accession number: Q6L126
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.