Q6KZ11 (SURE_PICTO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	PTO1456

Organism

Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) [Complete proteome] [HAMAP]

Taxonomic identifier

263820 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Picrophilaceae › Picrophilus

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	5'-nucleotidase surE HAMAP MF_00060		PRO_0000111868
Sites
	Metal binding	7	1	Divalent metal cation By similarity
	Metal binding	8	1	Divalent metal cation By similarity
	Metal binding	38	1	Divalent metal cation By similarity
	Metal binding	90	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6KZ11 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: FD088701992AD16F	FASTA	255	28,645
	10 20 30 40 50 60 MILVTNDDGY NSYGIRVLYR AAASIAESYI VAPDHGRSAT GMSTTYNVPL RAFKFDYGYA 70 80 90 100 110 120 ISGFPADSVY MARYALYNDK KIDLIVSGIN HGDNISLRSL YSSGTIGATM AGALIGIKGI 130 140 150 160 170 180 AFSMSYNGIS NEKIDLAEPY IKAIIENAME RFPDDVDILN VNFPGNLNRN TRILPARMSY 190 200 210 220 230 240 NIFDDNIIKR LDPNGHEYYW FGNKRHERCP ENCDYDVVYR KNSISITPIT VKGYLDDLRS 250 TEEFISFINV KELLG

References

[1]

"Genome sequence of Picrophilus torridus and its implications for life around pH 0." Fuetterer O., Angelov A., Liesegang H., Gottschalk G., Schleper C., Schepers B., Dock C., Antranikian G., Liebl W. Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096(2004) [PubMed: 15184674] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017261 Genomic DNA. Translation: AAT44041.1.
RefSeq	YP_024234.1. NC_005877.1.
3D structure databases
ProteinModelPortal	Q6KZ11.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2845171.
GenomeReviews	Gene locus PTO1456 in contig AE017261_GR.
KEGG	pto:PTO1456.
NMPDR	fig|263820.1.peg.1456.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	PAQDVRG.
PhylomeDB	Q6KZ11.
Enzyme and pathway databases
BioCyc	PTOR263820:PTO1456-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_PICTO

Accession

Primary (citable) accession number: Q6KZ11

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program