Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q6KYV3 (PGK_PICTO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:PTO1514
OrganismPicrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) [Complete proteome] [HAMAP]
Taxonomic identifier263820 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesPicrophilaceaePicrophilus

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 414414Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000146063

Regions

Nucleotide binding359 – 3624ATP By similarity
Region23 – 253Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site401Substrate By similarity
Binding site1181Substrate By similarity
Binding site1581Substrate By similarity
Binding site3331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6KYV3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: A6B5251BAC348775

FASTA41446,133
        10         20         30         40         50         60 
MNGSFFTMDD FDLDGKRIYL RIDINSPVNP ETGEILDDSR FRAYSKTINE LKSSKVVIVS 

        70         80         90        100        110        120 
HQSRPGKNDF TSLMGHARYM SNIIKKEIKF IDSLFSHDAI NAISNMSAGD IIMLENSRFY 

       130        140        150        160        170        180 
SEETLNADFE TIKNTHIVRR LSPLFDYYVI DAFPAIHRAQ TTLIGFKGSG PNIAGRLMER 

       190        200        210        220        230        240 
EITMLDKFKF FRGSPKIAIL AGSKIEDSIK VSRAFLKDNI VDYILTGGVV ANAFLYAGGF 

       250        260        270        280        290        300 
NIGRKNMEFI IKNNDNYESL INSATQLLQT FRGRILMPDD FLLSPSGRHV TISESINDDE 

       310        320        330        340        350        360 
IIADIGFNTV DKYSKIISRA SAIFMNGPMG IYEIPEYSIG TREIFNIVAE TPALKIAGGG 

       370        380        390        400        410 
HTLNALNSMH LTKKLDYTST GGGALINYLS GDSIPVIDAL IENKRLFGGK YNGR 

« Hide

References

[1]"Genome sequence of Picrophilus torridus and its implications for life around pH 0."
Fuetterer O., Angelov A., Liesegang H., Gottschalk G., Schleper C., Schepers B., Dock C., Antranikian G., Liebl W.
Proc. Natl. Acad. Sci. U.S.A. 101:9091-9096(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017261 Genomic DNA. Translation: AAT44099.1.
RefSeqYP_024292.1. NC_005877.1.

3D structure databases

ProteinModelPortalQ6KYV3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING263820.PTO1514.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT44099; AAT44099; PTO1514.
GeneID2844721.
KEGGpto:PTO1514.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMADMIFDIG.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycPTOR263820:GHA3-1565-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_PICTO
AccessionPrimary (citable) accession number: Q6KYV3
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways