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Q6KIG6 (SYR_MYCMO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:MMOB1240
OrganismMycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711) [Complete proteome] [HAMAP]
Taxonomic identifier267748 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length536 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 536536Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242050

Regions

Motif119 – 12911"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q6KIG6 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 187EFB7ECE782F7C

FASTA53662,086
        10         20         30         40         50         60 
MYIMKLLIKE ALEDALLKLN ISRKVILTDA KDFGDFSSNI AMVLQKDLGK NPLEIAQMIV 

        70         80         90        100        110        120 
EKINKEKFLI EKIEIVKPGF INFFLDHKFY VYLLEKFSKN DFLIELEKTY TYNLEYVSAN 

       130        140        150        160        170        180 
PTGFLHIGHA RGAAIGDTLA NILEFANNKV IREYYVNDAG NQISILAYAL YIRYQQILGN 

       190        200        210        220        230        240 
KTLNLPEDSY HGEDIKYFAK IFHKKYQEKF KNVDYSLEVE NFFKDEGVKI ALEKIKLDLK 

       250        260        270        280        290        300 
TFRVEFDLYT SEKSIYPLIE KSLKKLKNTY EQDGALWLKT TDYGDDKDRV LIKNDGTYTY 

       310        320        330        340        350        360 
FAPDLAYHYV KKTRSENVDY LIDFFGADHI GYVKRMQIAL EQFGFSKDTL NVLILEMVKL 

       370        380        390        400        410        420 
RKNGTEFVMS KRKGTAISLE DLIELIGVDN ARFFLVDHSS SSKLDLEIDL IAEKNLSNGA 

       430        440        450        460        470        480 
FIIQYAYART NSILEKTKVT LDVKLIRKPF DDKFEMKLVN VLKEFPILIE KIAENFKIHL 

       490        500        510        520        530 
LSQYLITLAK SFNSFYSNSK IIDSEEELKL ILLVKATQAV LKKGLDLLKV EAPERI 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017308 Genomic DNA. Translation: AAT27610.1.
RefSeqYP_015821.1. NC_006908.1.

3D structure databases

ProteinModelPortalQ6KIG6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267748.MMOB1240.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT27610; AAT27610; MMOB1240.
GeneID2807429.
KEGGmmo:MMOB1240.
PATRIC20015543. VBIMycMob32482_0133.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycMMOB267748:GH6Y-127-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_MYCMO
AccessionPrimary (citable) accession number: Q6KIG6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries