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Q6KI66 (EFTU_MYCMO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf
Ordered Locus Names:MMOB2240
OrganismMycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711) [Complete proteome] [HAMAP]
Taxonomic identifier267748 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Elongation factor Tu HAMAP-Rule MF_00118
PRO_1000015699

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding82 – 865GTP By similarity
Nucleotide binding137 – 1404GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6KI66 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 36F704420DF0145B

FASTA40043,968
        10         20         30         40         50         60 
MAKIDFDRSK EHVNIGTIGH VDHGKTTLTA AIATVLAKHV EGNEARDYGS IDNAPEERER 

        70         80         90        100        110        120 
GITINTSHIE YNTEKRHYAH VDCPGHADYV KNMITGAAQM DGAILVVAAT DGPMPQTREH 

       130        140        150        160        170        180 
ILLSKQVGVP KMVVFLNKVD LLGSGSEAEE MADLVEFEIR DLLSQYEFDG ENTPVVRGSA 

       190        200        210        220        230        240 
LKALNGEKAW EDKVMELMSQ VDNWIDAPLR EVDKPFLMAV EDVFTITGRG TVATGKVERG 

       250        260        270        280        290        300 
ELKINEEVDI VGYTEKPKRT TVTGIEMFRK NLKTALAGDN AGLLLRGINR EQIERGQVLA 

       310        320        330        340        350        360 
KPGTIVPHTK FKAAIYALKK EEGGRHTPFF KNYKPQFYFR TTDVTGGIEL PNNIEMVTPG 

       370        380        390        400 
DNVDLIVDLI SPIAVEVGTK FSIREGGRTV GAGSVTEIVK 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017308 Genomic DNA. Translation: AAT27710.1.
RefSeqYP_015921.1. NC_006908.1.

3D structure databases

ProteinModelPortalQ6KI66.
SMRQ6KI66. Positions 2-400.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267748.MMOB2240.

Proteomic databases

PRIDEQ6KI66.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT27710; AAT27710; MMOB2240.
GeneID2807800.
KEGGmmo:MMOB2240.
PATRIC20015767. VBIMycMob32482_0238.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMATIIPHTE.
OrthoDBEOG6R5C6X.

Enzyme and pathway databases

BioCycMMOB267748:GH6Y-234-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_MYCMO
AccessionPrimary (citable) accession number: Q6KI66
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families