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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciMMOB267748:GH6Y-295-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:MMOB2810
OrganismiMycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711)
Taxonomic identifieri267748 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000009072 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11881188DNA-directed RNA polymerase subunit betaPRO_0000224078Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi267748.MMOB2810.

Structurei

3D structure databases

ProteinModelPortaliQ6KI09.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiDIRDVHY.
OrthoDBiPOG091H01MI.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 2 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6KI09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKHKLRKFG PVTERRDYSQ TNRTWETFDF LETQKKSFKW FIDEGINQAL
60 70 80 90 100
NDIYPIHSNN GKVIIEYVNN SAKLEYKTDN EYKILAEARQ KGTTYSGILK
110 120 130 140 150
AKLTKTIVET GEIETAEVLY GDVPIMTSGG TFLINGSEKI IVSQLIRSPG
160 170 180 190 200
AYFGLKVRNK QADDLFNKLE IIPKLGSWIE ISHRVTGNTT DTVKVKIDKH
210 220 230 240 250
KAVSLVTFLR AMGMKKETIQ NLFGSHSTLE GENPILKETL NKEKFKTEDD
260 270 280 290 300
ALEYLYSVIW RGNNRITAES KSNLLSNILF NPRRYNLSKT GRYMLNRKLS
310 320 330 340 350
LVDRIIGTYL AEDLFSAKGT KNAKLVFAKG TLITREIAEK IQDSFKNNIF
360 370 380 390 400
NLIPIPDVSS DIYAAQLETN PKLAERIRVI SLNIYPNKTW MEQNTNPIIV
410 420 430 440 450
IANDPNSTEL HLLASDLVAI VSYYFNLVDR VGQDDDPDSL INKRIVGVGE
460 470 480 490 500
LLENQFKIGL SKLEKNAKER MSAKEIEKIT PKNITNSKPV YNQFKTFFNS
510 520 530 540 550
SKLSQFMDQV NPLAEISNKR RVTSLGPGGL NRETAQFEVR DVHSTHYGRI
560 570 580 590 600
CPIETPEGPN IGLILNFATY AKVNDFGFIQ SPYFKVNDGI IDYEKPIFLT
610 620 630 640 650
AAEEIDKKFA QSTVSVDKDG KITTQNITVR QNHDYLIVSP SEVDYIDISS
660 670 680 690 700
KQMTSIAAAA IPFLENNDAN RALMGSNMQR QAIPLLEAEA PLVATGIEAD
710 720 730 740 750
IAKFSVSNLI VKEEGEVSYV DGTKIKVKSK NDKSKTYYLK NFEHSNQGTL
760 770 780 790 800
LSQKPIVKLG DKVEIGDLLT DASSFKDGEM ALGKNVMIAF STWNGYNYED
810 820 830 840 850
AIVISERLVK DDVFTSVHIE DQTIQFRTSK AGSDKLTREI PNVSNFSKRN
860 870 880 890 900
LDEEGIVKVG SEVVAGDILV GRVSPKGEEN PSPEEKLLAA IFQKKPSTDK
910 920 930 940 950
DTSLKVKHGH AGTVLDVQVL SRASGDVLED SVEKIVKVSI AQKRKIKVGD
960 970 980 990 1000
KMAGRHGNKG VISIVAPVED MPHLEDGTVI DIILNPQGVP SRMNIGQVLE
1010 1020 1030 1040 1050
LHLGMAAKTL STKFVSPGFD GLKFGTIQEI LKEAKLPENG KFTLIDPMTG
1060 1070 1080 1090 1100
EKFDNKVSVG IMYMLKLSHM VDDKMHARSI GPYSLITQQP LGGKSQNGGQ
1110 1120 1130 1140 1150
RFGEMETWAL EAHGASNILQ EILTYKSDNI EGRKGLYNSL ATGNKIPAPG
1160 1170 1180
TPESFNVLSY ELRGLSIKLE SQAHFKNAQI VKEVMDNE
Length:1,188
Mass (Da):132,457
Last modified:July 5, 2004 - v1
Checksum:iC77B9C310A2D9ACF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017308 Genomic DNA. Translation: AAT27767.1.
RefSeqiWP_011264801.1. NC_006908.1.

Genome annotation databases

EnsemblBacteriaiAAT27767; AAT27767; MMOB2810.
KEGGimmo:MMOB2810.
PATRICi20015893. VBIMycMob32482_0297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017308 Genomic DNA. Translation: AAT27767.1.
RefSeqiWP_011264801.1. NC_006908.1.

3D structure databases

ProteinModelPortaliQ6KI09.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267748.MMOB2810.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT27767; AAT27767; MMOB2810.
KEGGimmo:MMOB2810.
PATRICi20015893. VBIMycMob32482_0297.

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiDIRDVHY.
OrthoDBiPOG091H01MI.

Enzyme and pathway databases

BioCyciMMOB267748:GH6Y-295-MONOMER.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 2 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOB_MYCMO
AccessioniPrimary (citable) accession number: Q6KI09
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.