Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q6KHA5

- Q6KHA5_MYCMO

UniProt

Q6KHA5 - Q6KHA5_MYCMO

Protein
Submitted name:

Leucyl-tRNA synthetase

Gene

leuS

Organism
Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. leucine-tRNA ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. leucyl-tRNA aminoacylation Source: InterPro

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetaseImported, Ligase

    Enzyme and pathway databases

    BioCyciMMOB267748:GH6Y-572-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Leucyl-tRNA synthetaseImported (EC:6.1.1.4Imported)
    Gene namesi
    Name:leuSImported
    Ordered Locus Names:MMOB5390Imported
    OrganismiMycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711)Imported
    Taxonomic identifieri267748 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000009072: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi267748.MMOB5390.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ZIUX-ray2.07A/B1-630[»]
    ProteinModelPortaliQ6KHA5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000200748.
    KOiK01869.
    OMAiWANELAT.
    OrthoDBiEOG63Z74X.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.40.50.620. 1 hit.
    InterProiIPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    [Graphical view]
    PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
    PfamiPF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 2 hits.
    [Graphical view]
    PRINTSiPR00985. TRNASYNTHLEU.
    SUPFAMiSSF47323. SSF47323. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q6KHA5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYNHNEIEKK WQTRWEKTKA FKTTNKSKDK FYALDMFPYP SGSGLHVGHP    50
    EGYTATDIIS RYKRLKGFDV LHPIGWDAFG LPAEQYALSS GKHPQPFTLK 100
    NIENFRRQLK SLGFSFDYEK EVNTTDPSYY RWTQWIFKQI YKKGLAEIRE 150
    VDVNWCPGLG TVLANEEIVE NDKGEMVSER GSFPVYKKPM KQWVLKITNY 200
    ADRLLEDLNL LDWPDSLKKL QTNWIGKEEI DGKITYKLQD WIFARQRYWG 250
    EPFPVYFDED NNVYLIDELV ELPHMENIMP SGTGEGPLAT NTEWVQYKKN 300
    NKIFKRDTNT MPQWAGSCWY YLAYIMKQED GTYLPIDSKK AYEAFSKWLP 350
    VDLYIGGQEH AVLHLLYARF WHKILYDLKI VPTKEPFQKL INQGMILGKD 400
    GQKMSKSLGN VVNPDEIIQN FGADTLRVYE MFMGPLTDTK KWNESTVEAT 450
    YKWILRVKRI FQIFIEDKSK INSLHKDDQF ISEHNLLIKE ITQDIEDLKF 500
    NIMISKLMIF VNSLYKKEKI YSLKPLKDFA IMFSTIAPHI SEELLESLGE 550
    KEIMFQSWPT YENNKILLTK DIVAIQVNGK LRETFEIEND WDEKRVIEEA 600
    KKLPNVKKHL ENKIIKKEIY IAKKILNFII 630
    Length:630
    Mass (Da):74,275
    Last modified:July 5, 2004 - v1
    Checksum:iBFFD6A92E79B2F2E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017308 Genomic DNA. Translation: AAT28025.1.
    RefSeqiWP_011265059.1. NC_006908.1.
    YP_016236.1. NC_006908.1.

    Genome annotation databases

    EnsemblBacteriaiAAT28025; AAT28025; MMOB5390.
    GeneIDi2807813.
    KEGGimmo:MMOB5390.
    PATRICi20016465. VBIMycMob32482_0566.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017308 Genomic DNA. Translation: AAT28025.1 .
    RefSeqi WP_011265059.1. NC_006908.1.
    YP_016236.1. NC_006908.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ZIU X-ray 2.07 A/B 1-630 [» ]
    ProteinModelPortali Q6KHA5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 267748.MMOB5390.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAT28025 ; AAT28025 ; MMOB5390 .
    GeneIDi 2807813.
    KEGGi mmo:MMOB5390.
    PATRICi 20016465. VBIMycMob32482_0566.

    Phylogenomic databases

    HOGENOMi HOG000200748.
    KOi K01869.
    OMAi WANELAT.
    OrthoDBi EOG63Z74X.

    Enzyme and pathway databases

    BioCyci MMOB267748:GH6Y-572-MONOMER.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.40.50.620. 1 hit.
    InterProi IPR002300. aa-tRNA-synth_Ia.
    IPR002302. Leu-tRNA-ligase.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    [Graphical view ]
    PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
    Pfami PF08264. Anticodon_1. 1 hit.
    PF00133. tRNA-synt_1. 2 hits.
    [Graphical view ]
    PRINTSi PR00985. TRNASYNTHLEU.
    SUPFAMi SSF47323. SSF47323. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43663 / 163K / NCTC 11711Imported.
    2. "Leucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in Mycoplasma pathogens."
      Li L., Palencia A., Lukk T., Li Z., Luthey-Schulten Z.A., Cusack S., Martinis S.A., Boniecki M.T.
      Proc. Natl. Acad. Sci. U.S.A. 110:3817-3822(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.07 ANGSTROMS).

    Entry informationi

    Entry nameiQ6KHA5_MYCMO
    AccessioniPrimary (citable) accession number: Q6KHA5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3