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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei285Proton donorUniRule annotation1
Active sitei306UniRule annotation1
Active sitei421UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMMOB267748:G1G0Z-602-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:MMOB5540
OrganismiMycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711)
Taxonomic identifieri267748 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000009072 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001806831 – 433Glucose-6-phosphate isomeraseAdd BLAST433

Interactioni

Protein-protein interaction databases

STRINGi267748.MMOB5540

Structurei

3D structure databases

ProteinModelPortaliQ6KH90
SMRiQ6KH90
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QYV Bacteria
COG0166 LUCA
HOGENOMiHOG000100403
KOiK01810
OMAiSFIIPDD
OrthoDBiPOG091H0EIM

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q6KH90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKIKLNLLN AIDSSEILNY KDQVKEINEK MNRFEMIGSD FLGWKDLPNQ
60 70 80 90 100
INWDEFLNME EKAKWLIKEN VEILVVIGIG GSYLGARAAI EFVNGTFPLS
110 120 130 140 150
GSKKLEIIYA GTNLSSTATA QLLAYVENKK FAINIISKSG TTLEPSIAFR
160 170 180 190 200
FFRELLEKKV GKAESRKFII ATTDANKGLL REIVRKEGYT SFIIPDDVGG
210 220 230 240 250
RYSVLTPVGL FPMLCAGLNV REILVGAQKS NDFYKKSDLE ENIAYQYAVA
260 270 280 290 300
RHIMHTQKKY AVEVLISYEP YFQYFLEWWK QLFGETEGKN ELGLYPSSKI
310 320 330 340 350
FSTDLHSLGQ FIQEGSRILF ETVINLKKPK IDLDISEDKE NFDGINYLVN
360 370 380 390 400
KTLHGINVAA LDATVSAHTD VAKVPNIILE IADSTEETLG WLFMFFERAC
410 420 430
AMSAYLLNLN PFNQPGVEVY KANMFKILGK PKK
Length:433
Mass (Da):49,050
Last modified:July 5, 2004 - v1
Checksum:i003A09A7DD5F5F93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017308 Genomic DNA Translation: AAT28040.1
RefSeqiWP_011265074.1, NC_006908.1

Genome annotation databases

EnsemblBacteriaiAAT28040; AAT28040; MMOB5540
KEGGimmo:MMOB5540

Similar proteinsi

Entry informationi

Entry nameiG6PI_MYCMO
AccessioniPrimary (citable) accession number: Q6KH90
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome